FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143134460> ?p ?o ?g. }

• W2143134460 endingPage "2650" @default.
• W2143134460 startingPage "2639" @default.
• W2143134460 abstract "To develop a novel four-dimensional (4D) intensity modulated radiation therapy (IMRT) treatment planning methodology based on dynamic virtual patient models.The 4D model-based planning (4DMP) is a predictive tracking method which consists of two main steps: (1) predicting the 3D deformable motion of the target and critical structures as a function of time during treatment delivery; (2) adjusting the delivery beam apertures formed by the dynamic multi-leaf collimators (DMLC) to account for the motion. The key feature of 4DMP is the application of a dynamic virtual patient model in motion prediction, treatment beam adjustment, and dose calculation. A lung case was chosen to demonstrate the feasibility of the 4DMP. For the lung case, a dynamic virtual patient model (4D model) was first developed based on the patient's 4DCT images. The 4D model was capable of simulating respiratory motion of different patterns. A model-based registration method was then applied to convert the 4D model into a set of deformation maps and 4DCT images for dosimetric purposes. Based on the 4D model, 4DMP treatment plans with different respiratory motion scenarios were developed. The quality of 4DMP plans was then compared with two other commonly used 4D planning methods: maximum intensity projection (MIP) and planning on individual phases (IP).Under regular periodic motion, 4DMP offered similar target coverage as MIP with much better normal tissue sparing. At breathing amplitude of 2 cm, the lung V20 was 23.9% for a MIP plan and 16.7% for a 4DMP plan. The plan quality was comparable between 4DMP and IP: PTV V97 was 93.8% for the IP plan and 93.6% for the 4DMP plan. Lung V20 of the 4DMP plan was 2.1% lower than that of the IP plan and Dmax to cord was 2.2 Gy higher. Under a real time irregular breathing pattern, 4DMP had the best plan quality. PTV V97 was 90.4% for a MIP plan, 88.6% for an IP plan and 94.1% for a 4DMP plan. Lung V20 was 20.1% for the MIP plan, 17.8% for the IP plan and 17.5% for the 4DMP plan. The deliverability of the real time 4DMP plan was proved by calculating the maximum leaf speed of the DMLC.The 4D model-based planning, which applies dynamic virtual patient models in IMRT treatment planning, can account for the real time deformable motion of the tumor under different breathing conditions. Under regular motion, the quality of 4DMP plans was comparable with IP and superior to MIP. Under realistic motion in which breathing amplitude and period change, 4DMP gave the best plan quality of the three 4D treatment planning techniques." @default.
• W2143134460 created "2016-06-24" @default.
• W2143134460 creator A5011977189 @default.
• W2143134460 creator A5026138314 @default.
• W2143134460 creator A5037051290 @default.
• W2143134460 date "2011-05-06" @default.
• W2143134460 modified "2023-10-14" @default.
• W2143134460 title "Real time 4D IMRT treatment planning based on a dynamic virtual patient model: Proof of concept" @default.
• W2143134460 cites W1975262667 @default.
• W2143134460 cites W1978105021 @default.
• W2143134460 cites W1985587133 @default.
• W2143134460 cites W1987394233 @default.
• W2143134460 cites W1991148066 @default.
• W2143134460 cites W1993367926 @default.
• W2143134460 cites W1996728714 @default.
• W2143134460 cites W1999020553 @default.
• W2143134460 cites W2002188523 @default.
• W2143134460 cites W2016272999 @default.
• W2143134460 cites W2016811299 @default.
• W2143134460 cites W2017609901 @default.
• W2143134460 cites W2019500906 @default.
• W2143134460 cites W2023560768 @default.
• W2143134460 cites W2025829764 @default.
• W2143134460 cites W2034921615 @default.
• W2143134460 cites W2037682643 @default.
• W2143134460 cites W2040164521 @default.
• W2143134460 cites W2056617450 @default.
• W2143134460 cites W2060559903 @default.
• W2143134460 cites W2064356714 @default.
• W2143134460 cites W2065164399 @default.
• W2143134460 cites W2065385932 @default.
• W2143134460 cites W2065585898 @default.
• W2143134460 cites W2068333777 @default.
• W2143134460 cites W2073524083 @default.
• W2143134460 cites W2076244694 @default.
• W2143134460 cites W2077757814 @default.
• W2143134460 cites W2084282858 @default.
• W2143134460 cites W2085320476 @default.
• W2143134460 cites W2090905466 @default.
• W2143134460 cites W2100002104 @default.
• W2143134460 cites W2109462047 @default.
• W2143134460 cites W2127480863 @default.
• W2143134460 cites W2142867204 @default.
• W2143134460 cites W2146414540 @default.
• W2143134460 cites W2157837968 @default.
• W2143134460 cites W2166064220 @default.
• W2143134460 doi "https://doi.org/10.1118/1.3578927" @default.
• W2143134460 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3107830" @default.
• W2143134460 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21776801" @default.
• W2143134460 hasPublicationYear "2011" @default.
• W2143134460 type Work @default.
• W2143134460 sameAs 2143134460 @default.
• W2143134460 citedByCount "13" @default.
• W2143134460 countsByYear W21431344602012 @default.
• W2143134460 countsByYear W21431344602013 @default.
• W2143134460 countsByYear W21431344602014 @default.
• W2143134460 countsByYear W21431344602015 @default.
• W2143134460 countsByYear W21431344602016 @default.
• W2143134460 countsByYear W21431344602018 @default.
• W2143134460 crossrefType "journal-article" @default.
• W2143134460 hasAuthorship W2143134460A5011977189 @default.
• W2143134460 hasAuthorship W2143134460A5026138314 @default.
• W2143134460 hasAuthorship W2143134460A5037051290 @default.
• W2143134460 hasBestOaLocation W21431344602 @default.
• W2143134460 hasConcept C104114177 @default.
• W2143134460 hasConcept C105702510 @default.
• W2143134460 hasConcept C11413529 @default.
• W2143134460 hasConcept C126838900 @default.
• W2143134460 hasConcept C138885662 @default.
• W2143134460 hasConcept C154945302 @default.
• W2143134460 hasConcept C166957645 @default.
• W2143134460 hasConcept C201645570 @default.
• W2143134460 hasConcept C2776401178 @default.
• W2143134460 hasConcept C2776505523 @default.
• W2143134460 hasConcept C2778533338 @default.
• W2143134460 hasConcept C2989005 @default.
• W2143134460 hasConcept C31972630 @default.
• W2143134460 hasConcept C39300077 @default.
• W2143134460 hasConcept C41008148 @default.
• W2143134460 hasConcept C41895202 @default.
• W2143134460 hasConcept C509550671 @default.
• W2143134460 hasConcept C509974204 @default.
• W2143134460 hasConcept C57493831 @default.
• W2143134460 hasConcept C71924100 @default.
• W2143134460 hasConcept C75088862 @default.
• W2143134460 hasConcept C95457728 @default.
• W2143134460 hasConceptScore W2143134460C104114177 @default.
• W2143134460 hasConceptScore W2143134460C105702510 @default.
• W2143134460 hasConceptScore W2143134460C11413529 @default.
• W2143134460 hasConceptScore W2143134460C126838900 @default.
• W2143134460 hasConceptScore W2143134460C138885662 @default.
• W2143134460 hasConceptScore W2143134460C154945302 @default.
• W2143134460 hasConceptScore W2143134460C166957645 @default.
• W2143134460 hasConceptScore W2143134460C201645570 @default.
• W2143134460 hasConceptScore W2143134460C2776401178 @default.
• W2143134460 hasConceptScore W2143134460C2776505523 @default.
• W2143134460 hasConceptScore W2143134460C2778533338 @default.
• W2143134460 hasConceptScore W2143134460C2989005 @default.

• next