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- W2143134583 abstract "α-L-fucose abolishes the activity of guinea pig migration inhibitory factor (MIF) on the macrophages. Other sugars such as α-D-glucose, ß-D-galactose, α-L-rhamnose, methyl-α-D-mannoside, and N-acetyl-ß-D-glucosamine had no effect. Theabolition of MIF activity by α-L-fucose was reversible. When macrophages were incubated with α-L-fucosidase, a glycosidase which splits terminal α-L-fucose from oligosaccharides, the macrophages no longer responded to MIF. On the other hand, MIF incubated with α-L-fucosidase was still active. These experiments strongly suggest that α-L-fucose comprises an essential part of a macrophage membrane receptor for MIF." @default.
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- W2143134583 date "1973-11-01" @default.
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- W2143134583 title "REQUIREMENT FOR α-<scp>L</scp>-FUCOSE ON THE MACROPHAGE MEMBRANE RECEPTOR FOR MIF" @default.
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- W2143134583 doi "https://doi.org/10.1084/jem.138.5.1065" @default.
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