Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143143007> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2143143007 abstract "The synthetic all-trans isomer of beta-carotene was recently shown to possess antioxidant properties towards the formation of oxidized low density lipoprotein. In the present study, the binding of the all-trans and the 9-cis isomers of beta-carotene to plasma lipoproteins was investigated, and the effect of these isomers on the susceptibility of plasma lipoprotein to lipid peroxidation and on macrophage uptake of oxidized LDL were studied. Both the synthetic all-trans isomer of beta-carotene and the natural beta-carotene from the algae Dunaliella Bardawil [which is composed of the all-trans (70%) and the 9-cis (30%) isomers], were found to bind similarly to all plasma lipoproteins, following the incubation of beta-carotene with purified lipoproteins or with whole plasma. Incubation of the beta-carotene isomers with whole plasma, followed by separation of the lipoproteins, revealed substantial carotene binding to very low density lipoprotein (VLDL) and to LDL and limited binding to high density lipoprotein (HDL). Lipid peroxidation of VLDL and LDL were significantly inhibited by beta-carotene. The synthetic beta-carotene, however, was twice as effective as the Dunaliella beta-carotene in inhibiting LDL lipid peroxidation (following LDL incubation with copper ions). Cellular degradation of oxidized lipoproteins (mediated via the scavenger receptor) was decreased by 40% and 18%, respectively, when they were prepared by incubation in the presence of synthetic or natural beta-carotene; the control oxidized LDL was prepared in the absence of beta-carotene.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2143143007 created "2016-06-24" @default.
- W2143143007 creator A5027091776 @default.
- W2143143007 creator A5052487247 @default.
- W2143143007 creator A5058729385 @default.
- W2143143007 date "1993-01-01" @default.
- W2143143007 modified "2023-10-18" @default.
- W2143143007 title "Preferential Inhibition of LDL Oxidation by the all-trans Isomer of β-Carotene in Comparison with 9-cis β-Carotene" @default.
- W2143143007 cites W1536941997 @default.
- W2143143007 cites W1590457525 @default.
- W2143143007 cites W1597723737 @default.
- W2143143007 cites W1775749144 @default.
- W2143143007 cites W1841006369 @default.
- W2143143007 cites W1857052429 @default.
- W2143143007 cites W1940168049 @default.
- W2143143007 cites W1940749427 @default.
- W2143143007 cites W1952543526 @default.
- W2143143007 cites W1979655335 @default.
- W2143143007 cites W1991827124 @default.
- W2143143007 cites W2004626457 @default.
- W2143143007 cites W2005182309 @default.
- W2143143007 cites W2017354690 @default.
- W2143143007 cites W2023709232 @default.
- W2143143007 cites W2033624890 @default.
- W2143143007 cites W2068053744 @default.
- W2143143007 cites W2078077774 @default.
- W2143143007 cites W2079984226 @default.
- W2143143007 cites W2104127258 @default.
- W2143143007 cites W2104573407 @default.
- W2143143007 cites W2108038378 @default.
- W2143143007 cites W2111551082 @default.
- W2143143007 cites W2120344355 @default.
- W2143143007 cites W2147908356 @default.
- W2143143007 cites W2162458714 @default.
- W2143143007 cites W2166433794 @default.
- W2143143007 cites W2313625470 @default.
- W2143143007 cites W2419084840 @default.
- W2143143007 doi "https://doi.org/10.1515/cclm.1993.31.2.83" @default.
- W2143143007 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8467013" @default.
- W2143143007 hasPublicationYear "1993" @default.
- W2143143007 type Work @default.
- W2143143007 sameAs 2143143007 @default.
- W2143143007 citedByCount "21" @default.
- W2143143007 countsByYear W21431430072013 @default.
- W2143143007 countsByYear W21431430072018 @default.
- W2143143007 countsByYear W21431430072020 @default.
- W2143143007 countsByYear W21431430072021 @default.
- W2143143007 countsByYear W21431430072023 @default.
- W2143143007 crossrefType "journal-article" @default.
- W2143143007 hasAuthorship W2143143007A5027091776 @default.
- W2143143007 hasAuthorship W2143143007A5052487247 @default.
- W2143143007 hasAuthorship W2143143007A5058729385 @default.
- W2143143007 hasBestOaLocation W21431430072 @default.
- W2143143007 hasConcept C185592680 @default.
- W2143143007 hasConcept C25642318 @default.
- W2143143007 hasConcept C2776998673 @default.
- W2143143007 hasConcept C2778004101 @default.
- W2143143007 hasConcept C2778163477 @default.
- W2143143007 hasConcept C2778859900 @default.
- W2143143007 hasConcept C2779620165 @default.
- W2143143007 hasConcept C2780072125 @default.
- W2143143007 hasConcept C2780829032 @default.
- W2143143007 hasConcept C28781525 @default.
- W2143143007 hasConcept C31903555 @default.
- W2143143007 hasConcept C55493867 @default.
- W2143143007 hasConcept C8243546 @default.
- W2143143007 hasConceptScore W2143143007C185592680 @default.
- W2143143007 hasConceptScore W2143143007C25642318 @default.
- W2143143007 hasConceptScore W2143143007C2776998673 @default.
- W2143143007 hasConceptScore W2143143007C2778004101 @default.
- W2143143007 hasConceptScore W2143143007C2778163477 @default.
- W2143143007 hasConceptScore W2143143007C2778859900 @default.
- W2143143007 hasConceptScore W2143143007C2779620165 @default.
- W2143143007 hasConceptScore W2143143007C2780072125 @default.
- W2143143007 hasConceptScore W2143143007C2780829032 @default.
- W2143143007 hasConceptScore W2143143007C28781525 @default.
- W2143143007 hasConceptScore W2143143007C31903555 @default.
- W2143143007 hasConceptScore W2143143007C55493867 @default.
- W2143143007 hasConceptScore W2143143007C8243546 @default.
- W2143143007 hasIssue "2" @default.
- W2143143007 hasLocation W21431430071 @default.
- W2143143007 hasLocation W21431430072 @default.
- W2143143007 hasLocation W21431430073 @default.
- W2143143007 hasOpenAccess W2143143007 @default.
- W2143143007 hasPrimaryLocation W21431430071 @default.
- W2143143007 hasRelatedWork W1975230021 @default.
- W2143143007 hasRelatedWork W1995779403 @default.
- W2143143007 hasRelatedWork W2016219609 @default.
- W2143143007 hasRelatedWork W2022456632 @default.
- W2143143007 hasRelatedWork W2072691183 @default.
- W2143143007 hasRelatedWork W2143143007 @default.
- W2143143007 hasRelatedWork W2399228319 @default.
- W2143143007 hasRelatedWork W2439084570 @default.
- W2143143007 hasRelatedWork W3146408448 @default.
- W2143143007 hasRelatedWork W405637334 @default.
- W2143143007 hasVolume "31" @default.
- W2143143007 isParatext "false" @default.
- W2143143007 isRetracted "false" @default.
- W2143143007 magId "2143143007" @default.
- W2143143007 workType "article" @default.