Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143168148> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2143168148 endingPage "792" @default.
- W2143168148 startingPage "788" @default.
- W2143168148 abstract "No standard, universally accepted therapy exists for patients with adenocarcinoma of the endometrium with peritoneal dissemination. We report mature outcomes of selected patients with this uncommon pattern of spread treated with whole abdomen radiotherapy (RT).A retrospective review was undertaken of all patients with a diagnosis of endometrial cancer referred to the Radiologic Associates of Sacramento Medical Group between January 1, 1988 and October 1, 1999. Eleven patients were identified who had surgically proven peritoneal dissemination (peritoneal seeding) treated with whole abdomen RT as the sole cytotoxic therapy after operative cytoreduction. Ten patients had International Federation of Obstetrics and Gynecology (1988) Stage IV disease at diagnosis, and one had peritoneal dissemination at the time of initial recurrence after hysterectomy for Stage I disease. RT was administered to the whole abdomen using 10-MV photons in fractions of 1.0 or 1.5 Gy. A cumulative dose of 30 Gy was given in all patients, with shielding used to reduce the dose to the liver and kidneys. Partial abdominal volumes (pelvis plus paraaortic nodes) received supplementary dose at 1.5-1.8 Gy/fraction to bring the cumulative dose within the limited volumes to 46.2-54 Gy.Four patients developed progressive cancer within 13 months of completion of whole abdomen RT. One additional patient died of hepatic venoocclusive disease (radiation hepatitis) 15 months after RT without evidence of cancer recurrence. Five patients were alive and clinically cancer free 55, 129, 131, 134, and 178 months after RT completion. One patient died of unrelated causes 79 months after treatment completion.Abdominal RT, in doses compatible with the acute and late tolerance of normal tissues, can eradicate small deposits of disseminated, intraperitoneal endometrial cancer. Currently, our patient selection criteria include limited peritoneal dissemination at diagnosis permitting complete surgical clearance (<1 mm residual) of visible and palpable disease, Grade 1 or 2 histologic features, lack of demonstrable extraabdominal metastasis, and absence of major medical contraindications." @default.
- W2143168148 created "2016-06-24" @default.
- W2143168148 creator A5032175009 @default.
- W2143168148 creator A5091501280 @default.
- W2143168148 creator A5091770473 @default.
- W2143168148 date "2003-07-01" @default.
- W2143168148 modified "2023-09-25" @default.
- W2143168148 title "Whole abdomen radiotherapy for patients with peritoneal dissemination of endometrial adenocarcinoma" @default.
- W2143168148 cites W1973873786 @default.
- W2143168148 cites W1977682158 @default.
- W2143168148 cites W1978624764 @default.
- W2143168148 cites W1980875246 @default.
- W2143168148 cites W1986993149 @default.
- W2143168148 cites W1990047085 @default.
- W2143168148 cites W1995318474 @default.
- W2143168148 cites W1998222452 @default.
- W2143168148 cites W2000243200 @default.
- W2143168148 cites W2007655235 @default.
- W2143168148 cites W2008437506 @default.
- W2143168148 cites W2015096497 @default.
- W2143168148 cites W2016558284 @default.
- W2143168148 cites W2022031145 @default.
- W2143168148 cites W2022775755 @default.
- W2143168148 cites W2025019316 @default.
- W2143168148 cites W2040947347 @default.
- W2143168148 cites W2045612810 @default.
- W2143168148 cites W2048925009 @default.
- W2143168148 cites W2049948093 @default.
- W2143168148 cites W2050170590 @default.
- W2143168148 cites W2056935976 @default.
- W2143168148 cites W2081986704 @default.
- W2143168148 cites W2099229638 @default.
- W2143168148 cites W2123052456 @default.
- W2143168148 cites W2125168783 @default.
- W2143168148 cites W2137495374 @default.
- W2143168148 cites W2225357122 @default.
- W2143168148 cites W4294306326 @default.
- W2143168148 doi "https://doi.org/10.1016/s0360-3016(03)00066-x" @default.
- W2143168148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12788186" @default.
- W2143168148 hasPublicationYear "2003" @default.
- W2143168148 type Work @default.
- W2143168148 sameAs 2143168148 @default.
- W2143168148 citedByCount "4" @default.
- W2143168148 countsByYear W21431681482013 @default.
- W2143168148 crossrefType "journal-article" @default.
- W2143168148 hasAuthorship W2143168148A5032175009 @default.
- W2143168148 hasAuthorship W2143168148A5091501280 @default.
- W2143168148 hasAuthorship W2143168148A5091770473 @default.
- W2143168148 hasConcept C121608353 @default.
- W2143168148 hasConcept C126322002 @default.
- W2143168148 hasConcept C126838900 @default.
- W2143168148 hasConcept C141071460 @default.
- W2143168148 hasConcept C2777088508 @default.
- W2143168148 hasConcept C2779983558 @default.
- W2143168148 hasConcept C2781182431 @default.
- W2143168148 hasConcept C509974204 @default.
- W2143168148 hasConcept C71924100 @default.
- W2143168148 hasConceptScore W2143168148C121608353 @default.
- W2143168148 hasConceptScore W2143168148C126322002 @default.
- W2143168148 hasConceptScore W2143168148C126838900 @default.
- W2143168148 hasConceptScore W2143168148C141071460 @default.
- W2143168148 hasConceptScore W2143168148C2777088508 @default.
- W2143168148 hasConceptScore W2143168148C2779983558 @default.
- W2143168148 hasConceptScore W2143168148C2781182431 @default.
- W2143168148 hasConceptScore W2143168148C509974204 @default.
- W2143168148 hasConceptScore W2143168148C71924100 @default.
- W2143168148 hasIssue "3" @default.
- W2143168148 hasLocation W21431681481 @default.
- W2143168148 hasLocation W21431681482 @default.
- W2143168148 hasOpenAccess W2143168148 @default.
- W2143168148 hasPrimaryLocation W21431681481 @default.
- W2143168148 hasRelatedWork W1586374228 @default.
- W2143168148 hasRelatedWork W2003938723 @default.
- W2143168148 hasRelatedWork W2047967234 @default.
- W2143168148 hasRelatedWork W2089201504 @default.
- W2143168148 hasRelatedWork W2118496982 @default.
- W2143168148 hasRelatedWork W2364998975 @default.
- W2143168148 hasRelatedWork W2369162477 @default.
- W2143168148 hasRelatedWork W2439875401 @default.
- W2143168148 hasRelatedWork W4238867864 @default.
- W2143168148 hasRelatedWork W2525756941 @default.
- W2143168148 hasVolume "56" @default.
- W2143168148 isParatext "false" @default.
- W2143168148 isRetracted "false" @default.
- W2143168148 magId "2143168148" @default.
- W2143168148 workType "article" @default.