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- W2143187208 abstract "The generation of cytolytic T lymphocytes (CTL) during the immune response directed against the syngeneic X-ray-induced BALB/c RLmale 1 leukemia has been described previously: T killer cells react with a tumor antigen of RLmale 1 cells, and the H-2Dd molecules of the target cells play some role in the interaction. The study of anti-RLmale 1 responses of [(C57BL/6 x BALB/c) x BALB/c] mice shows that the major histocompatibility complex controls the anti-RLmale 1 CTL reaction at a second level, through an Ir gene, with dominant responsiveness, probably mapping to the right of I-B and controlling the high or low-CTL responder phenotype. Another non-H-2 associated gene interferes with the H-2 linked Ir gene, a responder allele at the non-H-2 locus, being necessary for the expression of the high-responder phenotype at the Ir gene locus." @default.
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- W2143187208 date "1980-01-01" @default.
- W2143187208 modified "2023-09-27" @default.
- W2143187208 title "Cell-mediated anti-tumor response in the RL♂61 system II. Control of the T killer cells by an H-2-linked Ir gene interfering with non-H-2 factors" @default.
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- W2143187208 doi "https://doi.org/10.1002/eji.1830100106" @default.
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