FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143282141> ?p ?o ?g. }

• W2143282141 endingPage "112" @default.
• W2143282141 startingPage "105" @default.
• W2143282141 abstract "There is a need to identify new markers to assess recurrence risk in early-stage colorectal cancer (CRC) patients. We explored the prognostic impact of ether-a-gò-gò-related gene 1 channels and some hypoxia markers, in patients with nonmetastatic (stage I, II, and III) CRC.The expression of hERG1, vascular endothelial growth factor A (VEGF-A), glucose transporter 1, carbonic anhydrase IX (CA-IX), epidermal growth factor receptor (EGF-R), and p53 was tested by immunohistochemistry in 135 patients. The median follow-up was 35 months. Clinicopathologic parameters and overall survival were evaluated.hERG1 displayed a statistically significant association with Glut-1, VEGF-A, CA-IX, and EGF-R; p53 with VEGF-A and CA-IX; Glut-1 with the age of the patients; and EGF-R with TNM and mucin content. TNM and CA-IX were prognostic factors at the univariate analysis; TNM, hERG1, and Glut-1, at the multivariate analysis. Risk scores calculated from the final multivariate model allowed to stratify patients into four different risk groups: A) stage I-II, Glut-1 positivity, any hERG1; B) stage I-II, Glut-1 and hERG1 negativity; C) stage I-II, Glut-1 negativity, hERG1 positivity; D) stage III, any Glut-1 and any hERG1.hERG1 positivity with Glut-1 negativity identifies a patient group with poor prognosis within stage I-II CRC. The possibility that these patients might benefit from adjuvant therapy, independently from the TNM stage, is discussed.More robust prognostic and predictive markers, supplementing standard clinical and pathologic staging, are needed for node-negative patients." @default.
• W2143282141 created "2016-06-24" @default.
• W2143282141 creator A5001669766 @default.
• W2143282141 creator A5023215623 @default.
• W2143282141 creator A5028260155 @default.
• W2143282141 creator A5029640604 @default.
• W2143282141 creator A5037390475 @default.
• W2143282141 creator A5039759619 @default.
• W2143282141 creator A5064377949 @default.
• W2143282141 creator A5064858820 @default.
• W2143282141 creator A5075280975 @default.
• W2143282141 creator A5078954350 @default.
• W2143282141 creator A5080826945 @default.
• W2143282141 creator A5083367244 @default.
• W2143282141 date "2012-04-01" @default.
• W2143282141 modified "2023-09-30" @default.
• W2143282141 title "hERG1 Channels and Glut-1 as Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study" @default.
• W2143282141 cites W1493048246 @default.
• W2143282141 cites W1963923169 @default.
• W2143282141 cites W1965219770 @default.
• W2143282141 cites W1967621966 @default.
• W2143282141 cites W1971211622 @default.
• W2143282141 cites W1978506033 @default.
• W2143282141 cites W1992432096 @default.
• W2143282141 cites W1995819860 @default.
• W2143282141 cites W1999544013 @default.
• W2143282141 cites W2000820277 @default.
• W2143282141 cites W2019602861 @default.
• W2143282141 cites W2026411584 @default.
• W2143282141 cites W2062843221 @default.
• W2143282141 cites W2070817546 @default.
• W2143282141 cites W2080308138 @default.
• W2143282141 cites W2083402331 @default.
• W2143282141 cites W2083496553 @default.
• W2143282141 cites W2086127297 @default.
• W2143282141 cites W2088010622 @default.
• W2143282141 cites W2089787007 @default.
• W2143282141 cites W2091068407 @default.
• W2143282141 cites W2096016472 @default.
• W2143282141 cites W2117692326 @default.
• W2143282141 cites W2121057526 @default.
• W2143282141 cites W2127707929 @default.
• W2143282141 cites W2141768150 @default.
• W2143282141 cites W2142548235 @default.
• W2143282141 cites W2158487250 @default.
• W2143282141 cites W2158734599 @default.
• W2143282141 cites W2162102504 @default.
• W2143282141 cites W2162774299 @default.
• W2143282141 cites W2166113945 @default.
• W2143282141 cites W2168680994 @default.
• W2143282141 cites W2169524906 @default.
• W2143282141 cites W2172072217 @default.
• W2143282141 cites W4293241248 @default.
• W2143282141 doi "https://doi.org/10.1593/tlo.11250" @default.
• W2143282141 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3323932" @default.
• W2143282141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22496927" @default.
• W2143282141 hasPublicationYear "2012" @default.
• W2143282141 type Work @default.
• W2143282141 sameAs 2143282141 @default.
• W2143282141 citedByCount "46" @default.
• W2143282141 countsByYear W21432821412012 @default.
• W2143282141 countsByYear W21432821412013 @default.
• W2143282141 countsByYear W21432821412014 @default.
• W2143282141 countsByYear W21432821412015 @default.
• W2143282141 countsByYear W21432821412016 @default.
• W2143282141 countsByYear W21432821412017 @default.
• W2143282141 countsByYear W21432821412018 @default.
• W2143282141 countsByYear W21432821412019 @default.
• W2143282141 countsByYear W21432821412020 @default.
• W2143282141 countsByYear W21432821412021 @default.
• W2143282141 countsByYear W21432821412022 @default.
• W2143282141 countsByYear W21432821412023 @default.
• W2143282141 crossrefType "journal-article" @default.
• W2143282141 hasAuthorship W2143282141A5001669766 @default.
• W2143282141 hasAuthorship W2143282141A5023215623 @default.
• W2143282141 hasAuthorship W2143282141A5028260155 @default.
• W2143282141 hasAuthorship W2143282141A5029640604 @default.
• W2143282141 hasAuthorship W2143282141A5037390475 @default.
• W2143282141 hasAuthorship W2143282141A5039759619 @default.
• W2143282141 hasAuthorship W2143282141A5064377949 @default.
• W2143282141 hasAuthorship W2143282141A5064858820 @default.
• W2143282141 hasAuthorship W2143282141A5075280975 @default.
• W2143282141 hasAuthorship W2143282141A5078954350 @default.
• W2143282141 hasAuthorship W2143282141A5080826945 @default.
• W2143282141 hasAuthorship W2143282141A5083367244 @default.
• W2143282141 hasBestOaLocation W21432821411 @default.
• W2143282141 hasConcept C121608353 @default.
• W2143282141 hasConcept C126322002 @default.
• W2143282141 hasConcept C143998085 @default.
• W2143282141 hasConcept C144301174 @default.
• W2143282141 hasConcept C146357865 @default.
• W2143282141 hasConcept C151730666 @default.
• W2143282141 hasConcept C167734588 @default.
• W2143282141 hasConcept C2777025900 @default.
• W2143282141 hasConcept C2777982462 @default.
• W2143282141 hasConcept C2780091936 @default.
• W2143282141 hasConcept C38180746 @default.
• W2143282141 hasConcept C526805850 @default.

• next