FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143294211> ?p ?o ?g. }

• W2143294211 endingPage "1356" @default.
• W2143294211 startingPage "1349" @default.
• W2143294211 abstract "In a 12.5 cM genome-wide scan for psoriasis susceptibility loci, recombination-based tests revealed linkage to the HLA region (Zmmax = 3.52), as well as suggestive linkage to two novel regions: chromosome 16q (60–83.1 cM from pter, Zmax = 2.50), and chromosome 20p (7.5–25 cM from pter, Zmax = 2.62). All three regions yielded P values ≤ 0.01 by non-parametric analysis. Recombination-based and allele sharing methods also confirmed a previous report of a dominant susceptibility locus on distal chromosome 17q (108.2 cM from pter, Zmax = 2.09, GENEHUNTER P= 0.0056). We could not confirm a previously reported locus on distal chromosome 4q; however, a broad region of unclear significance was identified proximal to this proposed locus (153.6–178.4 cM from pter, Zmax = 1.01). Taken together with our recent results demonstrating linkage to HLA-B and -C, this genome-wide scan identifies a psoriasis susceptibility locus at HLA, confirms linkage to 17q, and recommends two novel genomic regions for further scrutiny. One of these regions (16q) overlaps with a recently-identified susceptibility locus for Crohn's disease. Psoriasis is much more common in patients with Crohn's disease than in controls, suggesting that an immunomodulatory locus capable of influencing both diseases may reside in this region." @default.
• W2143294211 created "2016-06-24" @default.
• W2143294211 creator A5003687305 @default.
• W2143294211 creator A5005798011 @default.
• W2143294211 creator A5006993541 @default.
• W2143294211 creator A5010173083 @default.
• W2143294211 creator A5010643311 @default.
• W2143294211 creator A5015004042 @default.
• W2143294211 creator A5016596918 @default.
• W2143294211 creator A5020068816 @default.
• W2143294211 creator A5039210100 @default.
• W2143294211 creator A5090142811 @default.
• W2143294211 creator A5030847193 @default.
• W2143294211 date "1997-08-01" @default.
• W2143294211 modified "2023-09-26" @default.
• W2143294211 title "Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan" @default.
• W2143294211 cites W120968873 @default.
• W2143294211 cites W1518689009 @default.
• W2143294211 cites W1540816832 @default.
• W2143294211 cites W185884186 @default.
• W2143294211 cites W1898314022 @default.
• W2143294211 cites W1964995490 @default.
• W2143294211 cites W1965265115 @default.
• W2143294211 cites W1968067289 @default.
• W2143294211 cites W1973937085 @default.
• W2143294211 cites W1974338715 @default.
• W2143294211 cites W1976741643 @default.
• W2143294211 cites W1984189392 @default.
• W2143294211 cites W1984704099 @default.
• W2143294211 cites W1991062093 @default.
• W2143294211 cites W2003702513 @default.
• W2143294211 cites W2009452164 @default.
• W2143294211 cites W2021706207 @default.
• W2143294211 cites W2035464895 @default.
• W2143294211 cites W2042103448 @default.
• W2143294211 cites W2050124261 @default.
• W2143294211 cites W2066751658 @default.
• W2143294211 cites W2074574224 @default.
• W2143294211 cites W2076758225 @default.
• W2143294211 cites W2090244113 @default.
• W2143294211 cites W2093065038 @default.
• W2143294211 cites W2107871825 @default.
• W2143294211 cites W2123466824 @default.
• W2143294211 cites W2130234221 @default.
• W2143294211 cites W2313540693 @default.
• W2143294211 cites W2401912404 @default.
• W2143294211 cites W2409131213 @default.
• W2143294211 cites W384681393 @default.
• W2143294211 cites W2489425802 @default.
• W2143294211 doi "https://doi.org/10.1093/hmg/6.8.1349" @default.
• W2143294211 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9259283" @default.
• W2143294211 hasPublicationYear "1997" @default.
• W2143294211 type Work @default.
• W2143294211 sameAs 2143294211 @default.
• W2143294211 citedByCount "390" @default.
• W2143294211 countsByYear W21432942112012 @default.
• W2143294211 countsByYear W21432942112013 @default.
• W2143294211 countsByYear W21432942112014 @default.
• W2143294211 countsByYear W21432942112015 @default.
• W2143294211 countsByYear W21432942112016 @default.
• W2143294211 countsByYear W21432942112017 @default.
• W2143294211 countsByYear W21432942112018 @default.
• W2143294211 countsByYear W21432942112019 @default.
• W2143294211 countsByYear W21432942112020 @default.
• W2143294211 countsByYear W21432942112021 @default.
• W2143294211 countsByYear W21432942112022 @default.
• W2143294211 countsByYear W21432942112023 @default.
• W2143294211 crossrefType "journal-article" @default.
• W2143294211 hasAuthorship W2143294211A5003687305 @default.
• W2143294211 hasAuthorship W2143294211A5005798011 @default.
• W2143294211 hasAuthorship W2143294211A5006993541 @default.
• W2143294211 hasAuthorship W2143294211A5010173083 @default.
• W2143294211 hasAuthorship W2143294211A5010643311 @default.
• W2143294211 hasAuthorship W2143294211A5015004042 @default.
• W2143294211 hasAuthorship W2143294211A5016596918 @default.
• W2143294211 hasAuthorship W2143294211A5020068816 @default.
• W2143294211 hasAuthorship W2143294211A5030847193 @default.
• W2143294211 hasAuthorship W2143294211A5039210100 @default.
• W2143294211 hasAuthorship W2143294211A5090142811 @default.
• W2143294211 hasBestOaLocation W21432942111 @default.
• W2143294211 hasConcept C104317684 @default.
• W2143294211 hasConcept C122735190 @default.
• W2143294211 hasConcept C141231307 @default.
• W2143294211 hasConcept C142870003 @default.
• W2143294211 hasConcept C180754005 @default.
• W2143294211 hasConcept C203014093 @default.
• W2143294211 hasConcept C2780564577 @default.
• W2143294211 hasConcept C30481170 @default.
• W2143294211 hasConcept C54355233 @default.
• W2143294211 hasConcept C84597430 @default.
• W2143294211 hasConcept C86803240 @default.
• W2143294211 hasConceptScore W2143294211C104317684 @default.
• W2143294211 hasConceptScore W2143294211C122735190 @default.
• W2143294211 hasConceptScore W2143294211C141231307 @default.
• W2143294211 hasConceptScore W2143294211C142870003 @default.
• W2143294211 hasConceptScore W2143294211C180754005 @default.
• W2143294211 hasConceptScore W2143294211C203014093 @default.
• W2143294211 hasConceptScore W2143294211C2780564577 @default.

• next