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• W2143319066 abstract "Ten spontaneous mammary gland tumors affecting guinea pigs (GP) were analyzed histologically and immunohistochemically. Histologically, 3 were benign (2 simple adenomas and 1 benign mixed tumor) and 7 were malignant (1 simple solid carcinoma and 6 simple tubulopapillary carcinomas). Immunohistochemical data revealed the glandular immunoprofile of all the tumors and suggested their ductal origin on the basis of cytokeratin 20 expression. Interestingly, cytokeratin 7 was detected in basal/myoepithelial cells. Further, all tumors were positive for type α estrogen and progesterone receptors, suggesting a role for steroid hormones in the development of these neoplasias in GP. This article describes the morphological and immunohistochemical features of the normal mammary gland and spontaneous mammary gland tumors in GP." @default.
• W2143319066 created "2016-06-24" @default.
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• W2143319066 date "2009-12-31" @default.
• W2143319066 modified "2023-10-10" @default.
• W2143319066 title "Morphological and Immunohistochemical Characterization of Spontaneous Mammary Gland Tumors in the Guinea Pig (<i>Cavia porcellus</i>)" @default.
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• W2143319066 doi "https://doi.org/10.1177/0300985809358426" @default.
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