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• W2143322862 abstract "Excessive release of proinflammatory cytokines from cells stimulated with lipopolysaccharide (LPS) or staphylococcal exotoxin (SE) mediates the pathophysiologic manifestations of septic shock. Tricyclodecan-9-yl (D609), an inhibitor of phosphatidylcholine-specific phospholipase C, suppressed LPS- or SE-induced cytokines and chemokines in human peripheral blood mononuclear cells. These data suggest a potential role for D609 in the treatment of septic shock." @default.
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• W2143322862 date "2001-03-01" @default.
• W2143322862 modified "2023-10-17" @default.
• W2143322862 title "Suppression of Endotoxin- and Staphylococcal Exotoxin-Induced Cytokines and Chemokines by a Phospholipase C Inhibitor in Human Peripheral Blood Mononuclear Cells" @default.
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• W2143322862 doi "https://doi.org/10.1128/cdli.8.2.449-453.2001" @default.
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