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- W2143391690 abstract "Differentiated thyroid cancer is a rare disease and until recently was considered to be sporadic. However, increasing evidence has been found for a genetic basis of this disease. In approximately 5% of patients the differentiated thyroid cancer is dominantly inherited. Several families with different syndromes, of which differentiated thyroid cancer is a feature, have already been described. However, until now, single genes explain only a minority of cases. We hypothesize that differentiated thyroid cancer is a polygenic disease. Data from epidemiologic studies, about occult and multifocal carcinomas and the different response to specific risk factors contribute to this hypothesis." @default.
- W2143391690 created "2016-06-24" @default.
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- W2143391690 date "2001-12-01" @default.
- W2143391690 modified "2023-10-14" @default.
- W2143391690 title "Differentiated Thyroid Carcinoma: A Polygenic Disease" @default.
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- W2143391690 doi "https://doi.org/10.1089/10507250152740975" @default.
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