FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143405521> ?p ?o ?g. }

• W2143405521 endingPage "1934" @default.
• W2143405521 startingPage "1928" @default.
• W2143405521 abstract "Cells of solid malignancies generally adapt to entire lack of oxygen. Hypoxia induces the expression of several genes, which allows the cells to survive. For DNA transcription, it is necessary that DNA structure is loosened. In addition to structural characteristics of DNA, its epigenetic alterations influence a proper DNA transcription. Since histones play a key role in epigenetics, changes in expression levels of acetylated histones H3 and H4 as well as of hypoxia-inducible factor-1α (HIF-1α) in human neuroblastoma cell lines cultivated under standard or hypoxic conditions (1% O2) were investigated. Moreover, the effect of hypoxia on the expression of two transcription factors, c-Myc and N-myc, was studied. Hypoxic stress increased levels of acetylated histones H3 and H4 in UKF-NB-3 and UKF-NB-4 neuroblastoma cells with N-myc amplification, whereas almost no changes in acetylation of these histones were found in an SK-N-AS neuroblastoma cell line, the line with diploid N-myc status. An increase in histone H4 acetylation caused by hypoxia in UKF-NB-3 and UKF-NB-4 corresponds to increased levels of N-myc transcription factor in these cells." @default.
• W2143405521 created "2016-06-24" @default.
• W2143405521 creator A5008388003 @default.
• W2143405521 creator A5009212415 @default.
• W2143405521 creator A5009700689 @default.
• W2143405521 creator A5013532796 @default.
• W2143405521 creator A5019351423 @default.
• W2143405521 creator A5039781517 @default.
• W2143405521 creator A5074854374 @default.
• W2143405521 creator A5077879348 @default.
• W2143405521 creator A5079552959 @default.
• W2143405521 date "2014-01-27" @default.
• W2143405521 modified "2023-10-01" @default.
• W2143405521 title "Hypoxia-mediated histone acetylation and expression of N-myc transcription factor dictate aggressiveness of neuroblastoma cells" @default.
• W2143405521 cites W1493048246 @default.
• W2143405521 cites W1951128322 @default.
• W2143405521 cites W1965029808 @default.
• W2143405521 cites W1974317126 @default.
• W2143405521 cites W1981591956 @default.
• W2143405521 cites W1985444222 @default.
• W2143405521 cites W2009211112 @default.
• W2143405521 cites W2009871251 @default.
• W2143405521 cites W2027666726 @default.
• W2143405521 cites W2052864542 @default.
• W2143405521 cites W2067606868 @default.
• W2143405521 cites W2069698188 @default.
• W2143405521 cites W2070399051 @default.
• W2143405521 cites W2085609942 @default.
• W2143405521 cites W2085656281 @default.
• W2143405521 cites W2096083625 @default.
• W2143405521 cites W2097669240 @default.
• W2143405521 cites W2125257427 @default.
• W2143405521 cites W2138809862 @default.
• W2143405521 cites W2141783813 @default.
• W2143405521 cites W2143892143 @default.
• W2143405521 cites W2144691110 @default.
• W2143405521 cites W2146481527 @default.
• W2143405521 cites W2161688817 @default.
• W2143405521 cites W2164875406 @default.
• W2143405521 cites W2167479466 @default.
• W2143405521 cites W2326525648 @default.
• W2143405521 cites W2327054845 @default.
• W2143405521 cites W4382140905 @default.
• W2143405521 doi "https://doi.org/10.3892/or.2014.2999" @default.
• W2143405521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24481548" @default.
• W2143405521 hasPublicationYear "2014" @default.
• W2143405521 type Work @default.
• W2143405521 sameAs 2143405521 @default.
• W2143405521 citedByCount "18" @default.
• W2143405521 countsByYear W21434055212015 @default.
• W2143405521 countsByYear W21434055212016 @default.
• W2143405521 countsByYear W21434055212018 @default.
• W2143405521 countsByYear W21434055212019 @default.
• W2143405521 countsByYear W21434055212020 @default.
• W2143405521 countsByYear W21434055212021 @default.
• W2143405521 countsByYear W21434055212022 @default.
• W2143405521 countsByYear W21434055212023 @default.
• W2143405521 crossrefType "journal-article" @default.
• W2143405521 hasAuthorship W2143405521A5008388003 @default.
• W2143405521 hasAuthorship W2143405521A5009212415 @default.
• W2143405521 hasAuthorship W2143405521A5009700689 @default.
• W2143405521 hasAuthorship W2143405521A5013532796 @default.
• W2143405521 hasAuthorship W2143405521A5019351423 @default.
• W2143405521 hasAuthorship W2143405521A5039781517 @default.
• W2143405521 hasAuthorship W2143405521A5074854374 @default.
• W2143405521 hasAuthorship W2143405521A5077879348 @default.
• W2143405521 hasAuthorship W2143405521A5079552959 @default.
• W2143405521 hasBestOaLocation W21434055211 @default.
• W2143405521 hasConcept C104317684 @default.
• W2143405521 hasConcept C119157956 @default.
• W2143405521 hasConcept C138885662 @default.
• W2143405521 hasConcept C153911025 @default.
• W2143405521 hasConcept C179926584 @default.
• W2143405521 hasConcept C2776715637 @default.
• W2143405521 hasConcept C2779085176 @default.
• W2143405521 hasConcept C2781018059 @default.
• W2143405521 hasConcept C29537977 @default.
• W2143405521 hasConcept C41091548 @default.
• W2143405521 hasConcept C41895202 @default.
• W2143405521 hasConcept C502942594 @default.
• W2143405521 hasConcept C54355233 @default.
• W2143405521 hasConcept C552990157 @default.
• W2143405521 hasConcept C64927066 @default.
• W2143405521 hasConcept C81885089 @default.
• W2143405521 hasConcept C86339819 @default.
• W2143405521 hasConcept C86803240 @default.
• W2143405521 hasConcept C95444343 @default.
• W2143405521 hasConceptScore W2143405521C104317684 @default.
• W2143405521 hasConceptScore W2143405521C119157956 @default.
• W2143405521 hasConceptScore W2143405521C138885662 @default.
• W2143405521 hasConceptScore W2143405521C153911025 @default.
• W2143405521 hasConceptScore W2143405521C179926584 @default.
• W2143405521 hasConceptScore W2143405521C2776715637 @default.
• W2143405521 hasConceptScore W2143405521C2779085176 @default.
• W2143405521 hasConceptScore W2143405521C2781018059 @default.
• W2143405521 hasConceptScore W2143405521C29537977 @default.
• W2143405521 hasConceptScore W2143405521C41091548 @default.
• W2143405521 hasConceptScore W2143405521C41895202 @default.

• next