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• W2143406908 endingPage "1367" @default.
• W2143406908 startingPage "1365" @default.
• W2143406908 abstract "Kinetoplast DNA minicircles from various species of trypanosomes are heterogeneous in nucleotide sequence to various degrees but in all instances contain a conserved sequence region of 100 to 200 base pairs present in one, two, or four copies per minicircle. Comparison of the conserved sequence regions of minicircles from eight species of trypanosomes revealed a common sequence motif consisting of three conserved sequence blocks (CSBs) present in the same order and with similar spacing in all species. In addition to the invariant 12-base-pair universal minicircle sequence (CSB-3), a 10-base-pair sequence (CSB-1) and an 8-base-pair sequence (CSB-2) are highly conserved in all minicircles. The overlap of CSB-1 and CSB-3 with previously identified 5' termini of newly synthesized minicircle H and L strands, respectively, and the presence of this conserved sequence motif in minicircles from diverse species suggest that these CSBs may determine a common mechanism of minicircle replication." @default.
• W2143406908 created "2016-06-24" @default.
• W2143406908 creator A5045871906 @default.
• W2143406908 date "1989-03-01" @default.
• W2143406908 modified "2023-09-27" @default.
• W2143406908 title "Conserved sequence blocks in kinetoplast minicircles from diverse species of trypanosomes." @default.
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• W2143406908 doi "https://doi.org/10.1128/mcb.9.3.1365" @default.
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• W2143406908 hasPublicationYear "1989" @default.
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