Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143477354> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2143477354 endingPage "1180" @default.
- W2143477354 startingPage "1171" @default.
- W2143477354 abstract "Abstract The stereochemistry of 16α-fluoro-5-androsten-17-one (1) was determined by nmr spectroscopy and X-ray diffraction. The γ-effects of the fluorine atom in 13C nmr were used as a first stereochemical probe for the α-fluorine configuration. The magnitude of 3J (HH) measured on the H-16 multiplet of the 300 MHz 1H nmr spectrum of compound 1, was used with Karplus-type plots for the CH2CHF fragment of the two possible epimers. The plots show that only the α-fluorine configuration fits with the observed 3J (HH), and X-ray diffraction confirms such result. The dihedral angles estimated from the Karplus-type plot were consistent with the angles found by X-ray. Crystallographic data of compound 1 show the following ring conformations: A is a chair, B is an 8β, 9α-half-chair, C is a chair and D is a C(13)β-envelope. Key Words: Fluorinated dehydroandrosteroneproton-nmrcarbon-nmrKarplus-type plotsX-ray" @default.
- W2143477354 created "2016-06-24" @default.
- W2143477354 creator A5067490486 @default.
- W2143477354 creator A5074559376 @default.
- W2143477354 date "1993-08-01" @default.
- W2143477354 modified "2023-10-18" @default.
- W2143477354 title "Determination of the Structure and Configuration of 16α-Fluoro-5-androsten-17-one by NMR Spectroscopy and X-ray Diffraction" @default.
- W2143477354 cites W1978512205 @default.
- W2143477354 cites W2017560840 @default.
- W2143477354 cites W2024365799 @default.
- W2143477354 cites W2051743481 @default.
- W2143477354 cites W2091975693 @default.
- W2143477354 cites W2095408194 @default.
- W2143477354 cites W2115723594 @default.
- W2143477354 doi "https://doi.org/10.1080/00387019308011601" @default.
- W2143477354 hasPublicationYear "1993" @default.
- W2143477354 type Work @default.
- W2143477354 sameAs 2143477354 @default.
- W2143477354 citedByCount "0" @default.
- W2143477354 crossrefType "journal-article" @default.
- W2143477354 hasAuthorship W2143477354A5067490486 @default.
- W2143477354 hasAuthorship W2143477354A5074559376 @default.
- W2143477354 hasConcept C111429119 @default.
- W2143477354 hasConcept C112887158 @default.
- W2143477354 hasConcept C116447816 @default.
- W2143477354 hasConcept C120665830 @default.
- W2143477354 hasConcept C121332964 @default.
- W2143477354 hasConcept C122707536 @default.
- W2143477354 hasConcept C147789679 @default.
- W2143477354 hasConcept C178790620 @default.
- W2143477354 hasConcept C185592680 @default.
- W2143477354 hasConcept C203130289 @default.
- W2143477354 hasConcept C205860874 @default.
- W2143477354 hasConcept C207114421 @default.
- W2143477354 hasConcept C2779328170 @default.
- W2143477354 hasConcept C2780378348 @default.
- W2143477354 hasConcept C32891209 @default.
- W2143477354 hasConcept C32909587 @default.
- W2143477354 hasConcept C41008148 @default.
- W2143477354 hasConcept C50515024 @default.
- W2143477354 hasConcept C506198293 @default.
- W2143477354 hasConcept C554190296 @default.
- W2143477354 hasConcept C62520636 @default.
- W2143477354 hasConcept C65155139 @default.
- W2143477354 hasConcept C66974803 @default.
- W2143477354 hasConcept C71240020 @default.
- W2143477354 hasConcept C76155785 @default.
- W2143477354 hasConcept C8010536 @default.
- W2143477354 hasConcept C89025888 @default.
- W2143477354 hasConceptScore W2143477354C111429119 @default.
- W2143477354 hasConceptScore W2143477354C112887158 @default.
- W2143477354 hasConceptScore W2143477354C116447816 @default.
- W2143477354 hasConceptScore W2143477354C120665830 @default.
- W2143477354 hasConceptScore W2143477354C121332964 @default.
- W2143477354 hasConceptScore W2143477354C122707536 @default.
- W2143477354 hasConceptScore W2143477354C147789679 @default.
- W2143477354 hasConceptScore W2143477354C178790620 @default.
- W2143477354 hasConceptScore W2143477354C185592680 @default.
- W2143477354 hasConceptScore W2143477354C203130289 @default.
- W2143477354 hasConceptScore W2143477354C205860874 @default.
- W2143477354 hasConceptScore W2143477354C207114421 @default.
- W2143477354 hasConceptScore W2143477354C2779328170 @default.
- W2143477354 hasConceptScore W2143477354C2780378348 @default.
- W2143477354 hasConceptScore W2143477354C32891209 @default.
- W2143477354 hasConceptScore W2143477354C32909587 @default.
- W2143477354 hasConceptScore W2143477354C41008148 @default.
- W2143477354 hasConceptScore W2143477354C50515024 @default.
- W2143477354 hasConceptScore W2143477354C506198293 @default.
- W2143477354 hasConceptScore W2143477354C554190296 @default.
- W2143477354 hasConceptScore W2143477354C62520636 @default.
- W2143477354 hasConceptScore W2143477354C65155139 @default.
- W2143477354 hasConceptScore W2143477354C66974803 @default.
- W2143477354 hasConceptScore W2143477354C71240020 @default.
- W2143477354 hasConceptScore W2143477354C76155785 @default.
- W2143477354 hasConceptScore W2143477354C8010536 @default.
- W2143477354 hasConceptScore W2143477354C89025888 @default.
- W2143477354 hasIssue "7" @default.
- W2143477354 hasLocation W21434773541 @default.
- W2143477354 hasOpenAccess W2143477354 @default.
- W2143477354 hasPrimaryLocation W21434773541 @default.
- W2143477354 hasRelatedWork W1941687519 @default.
- W2143477354 hasRelatedWork W1963664099 @default.
- W2143477354 hasRelatedWork W1967076821 @default.
- W2143477354 hasRelatedWork W2052818805 @default.
- W2143477354 hasRelatedWork W2076127470 @default.
- W2143477354 hasRelatedWork W2380341149 @default.
- W2143477354 hasRelatedWork W2899776404 @default.
- W2143477354 hasRelatedWork W3041003813 @default.
- W2143477354 hasRelatedWork W3092961736 @default.
- W2143477354 hasRelatedWork W3207394681 @default.
- W2143477354 hasVolume "26" @default.
- W2143477354 isParatext "false" @default.
- W2143477354 isRetracted "false" @default.
- W2143477354 magId "2143477354" @default.
- W2143477354 workType "article" @default.