Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143523785> ?p ?o ?g. }
- W2143523785 endingPage "399" @default.
- W2143523785 startingPage "387" @default.
- W2143523785 abstract "Neuronatin (Nnat) is an imprinted gene that is expressed exclusively from the paternal allele while the maternal allele is silent and methylated. The Nnat locus exhibits some unique features compared with other imprinted domains. Unlike the majority of imprinted genes, which are organised in clusters and coordinately regulated, Nnat does not appear to be closely linked to other imprinted genes. Also unusually, Nnat is located within an 8-kb intron of the Bc10 gene, which generates a biallelically expressed, antisense transcript. A similar organisation is conserved at the human NNAT locus on chromosome 20. Nnat expression is first detected at E8.5 in rhombomeres 3 and 5, and subsequently, expression is widespread within postmitotic neuronal tissues. Using modified BAC transgenes, we show that imprinted expression of Nnat at ectopic sites requires, at most, an 80-kb region around the gene. Furthermore, reporter transgenes reveal distinct and dispersed cis-regulatory elements that direct tissue-specific expression and these are predominantly upstream of the region that confers allele-specific expression." @default.
- W2143523785 created "2016-06-24" @default.
- W2143523785 creator A5003842825 @default.
- W2143523785 creator A5021300056 @default.
- W2143523785 creator A5034435341 @default.
- W2143523785 creator A5054698548 @default.
- W2143523785 creator A5057950464 @default.
- W2143523785 creator A5064667910 @default.
- W2143523785 creator A5064938945 @default.
- W2143523785 creator A5074271128 @default.
- W2143523785 creator A5084947394 @default.
- W2143523785 date "2001-08-01" @default.
- W2143523785 modified "2023-10-06" @default.
- W2143523785 title "Imprinted Expression of Neuronatin from Modified BAC Transgenes Reveals Regulation by Distinct and Distant Enhancers" @default.
- W2143523785 cites W1534122645 @default.
- W2143523785 cites W1590914074 @default.
- W2143523785 cites W1609534144 @default.
- W2143523785 cites W1643500256 @default.
- W2143523785 cites W1646817159 @default.
- W2143523785 cites W1669374546 @default.
- W2143523785 cites W1755314328 @default.
- W2143523785 cites W1804006179 @default.
- W2143523785 cites W1967071065 @default.
- W2143523785 cites W1970240837 @default.
- W2143523785 cites W1971235075 @default.
- W2143523785 cites W1981509506 @default.
- W2143523785 cites W1981849389 @default.
- W2143523785 cites W1981889222 @default.
- W2143523785 cites W1986011018 @default.
- W2143523785 cites W1987909487 @default.
- W2143523785 cites W1995574948 @default.
- W2143523785 cites W2000819178 @default.
- W2143523785 cites W2012943045 @default.
- W2143523785 cites W2013275556 @default.
- W2143523785 cites W2029892976 @default.
- W2143523785 cites W2034403814 @default.
- W2143523785 cites W2034603636 @default.
- W2143523785 cites W2035460225 @default.
- W2143523785 cites W2035939797 @default.
- W2143523785 cites W2039298424 @default.
- W2143523785 cites W2043203820 @default.
- W2143523785 cites W2050558334 @default.
- W2143523785 cites W2056156549 @default.
- W2143523785 cites W2058471882 @default.
- W2143523785 cites W2070766068 @default.
- W2143523785 cites W2071800537 @default.
- W2143523785 cites W2075832020 @default.
- W2143523785 cites W2082968298 @default.
- W2143523785 cites W2084101481 @default.
- W2143523785 cites W2094697218 @default.
- W2143523785 cites W2115430605 @default.
- W2143523785 cites W2115497164 @default.
- W2143523785 cites W2119889600 @default.
- W2143523785 cites W2127639335 @default.
- W2143523785 cites W2150636197 @default.
- W2143523785 cites W2156927986 @default.
- W2143523785 cites W2162228202 @default.
- W2143523785 cites W2163035954 @default.
- W2143523785 cites W2164331758 @default.
- W2143523785 cites W2174023711 @default.
- W2143523785 cites W2185773995 @default.
- W2143523785 cites W2261823003 @default.
- W2143523785 cites W4213185988 @default.
- W2143523785 doi "https://doi.org/10.1006/dbio.2001.0327" @default.
- W2143523785 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11476579" @default.
- W2143523785 hasPublicationYear "2001" @default.
- W2143523785 type Work @default.
- W2143523785 sameAs 2143523785 @default.
- W2143523785 citedByCount "54" @default.
- W2143523785 countsByYear W21435237852013 @default.
- W2143523785 countsByYear W21435237852014 @default.
- W2143523785 countsByYear W21435237852016 @default.
- W2143523785 countsByYear W21435237852017 @default.
- W2143523785 countsByYear W21435237852018 @default.
- W2143523785 countsByYear W21435237852019 @default.
- W2143523785 countsByYear W21435237852020 @default.
- W2143523785 countsByYear W21435237852022 @default.
- W2143523785 countsByYear W21435237852023 @default.
- W2143523785 crossrefType "journal-article" @default.
- W2143523785 hasAuthorship W2143523785A5003842825 @default.
- W2143523785 hasAuthorship W2143523785A5021300056 @default.
- W2143523785 hasAuthorship W2143523785A5034435341 @default.
- W2143523785 hasAuthorship W2143523785A5054698548 @default.
- W2143523785 hasAuthorship W2143523785A5057950464 @default.
- W2143523785 hasAuthorship W2143523785A5064667910 @default.
- W2143523785 hasAuthorship W2143523785A5064938945 @default.
- W2143523785 hasAuthorship W2143523785A5074271128 @default.
- W2143523785 hasAuthorship W2143523785A5084947394 @default.
- W2143523785 hasBestOaLocation W21435237851 @default.
- W2143523785 hasConcept C102230213 @default.
- W2143523785 hasConcept C104317684 @default.
- W2143523785 hasConcept C111936080 @default.
- W2143523785 hasConcept C150194340 @default.
- W2143523785 hasConcept C165864922 @default.
- W2143523785 hasConcept C180754005 @default.
- W2143523785 hasConcept C190727270 @default.
- W2143523785 hasConcept C201492766 @default.
- W2143523785 hasConcept C21592294 @default.