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• W2143562577 abstract "Evaluar la evolución del uso de ranelato de estroncio tras la publicación de una alerta sanitaria en noviembre de 2007 sobre los riesgos de desarrollo de DRESS (Drug Rash with Eosinophilia and Sistemic Symptoms) por este medicamento. Se calculan las DHD (dosis diarias definidas/1.000 habitantes/día) mensuales de ranelato de estroncio entre 2006 y 2008 en un área sanitaria de España. Se analizan los datos gráficamente y mediante un modelo de regresión múltiple. La representación gráfica muestra una tendencia a largo plazo creciente durante todo el periodo de estudio, aunque el ritmo de crecimiento es inferior después de la emisión de la alerta. El modelo de regresión múltiple muestra que la alerta sanitaria resulta ser estadísticamente significativa. La utilización de ranelato de estroncio sigue creciendo después de la emisión de la alerta sanitaria, aunque a un ritmo menor que antes. To evaluate changes in the use of strontium ranelate following a health safety warning in November 2007 on the risks of the development of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) with the use of this medicine. Monthly strontium ranelate DHD (daily defined doses/1,000 inhabitants/day) were calculated between 2006 and 2008 in a health area of Spain. The data were analyzed graphically and through a multiple regression model. Graphical representation showed a long-term rising trend throughout the study period, although growth slowed after the safety warning was issued. The multiple regression model showed that the health warning was statistically significant. The use of strontium ranelate continues to grow after the issue of the health safety warning, although at a slower pace than previously." @default.
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• W2143562577 date "2010-03-01" @default.
• W2143562577 modified "2023-10-17" @default.
• W2143562577 title "Impacto de una alerta sanitaria sobre la utilización de ranelato de estroncio" @default.
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• W2143562577 doi "https://doi.org/10.1016/j.gaceta.2009.10.012" @default.
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