FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143670718> ?p ?o ?g. }

• W2143670718 endingPage "1746" @default.
• W2143670718 startingPage "1736" @default.
• W2143670718 abstract "Acetylcholinesterase inhibitors (ACIs), e.g., neostigmine, are known to increase upper and lower gastrointestinal (GI) motility and are used to treat acute colonic pseudoobstruction. However, their effects on gastroduodenal motility in humans are poorly understood. Our hypotheses were that, in patients with suspected GI motility disorders, neostigmine increases gastric and small intestinal motor activity, and these effects are greater in patients with cardiovagal neuropathy, reflecting denervation sensitivity.In this open label study, the effects of neostigmine (1 mg intravenously) on gastroduodenal motor activity recorded with manometry were assessed in 28 patients with a suspected GI motility disorder. Cardiovagal function was assessed with the heart rate response to deep breathing and GI transit by scintigraphy.The final diagnoses were gastroparesis (6 patients), gastroparesis with intestinal neuropathy (3 patients), intestinal neuropathy or pseudoobstruction (5 patients), functional dyspepsia (6 patients), chronic abdominal pain (3 patients), mechanical small intestinal obstruction (3 patients), and pelvic floor dysfunction (2 patients). Neostigmine increased both antral and intestinal phasic pressure activity (p < 0.001). Neostigmine increased antral and intestinal pressure activity in 81% and 50% of patients with reduced postprandial antral and intestinal contractile responses to meal, respectively. The antroduodenal pressure response to neostigmine was not higher in patients with cardiovagal dysfunction.Neostigmine increased antral and intestinal motor activity in patients with hypomotility, including intestinal dysmotility. These responses to neostigmine were not greater in patients with cardiovagal dysfunction. The use of longer-acting ACIs for treating antroduodenal dysmotility warrant further study." @default.
• W2143670718 created "2016-06-24" @default.
• W2143670718 creator A5001729912 @default.
• W2143670718 creator A5029520025 @default.
• W2143670718 creator A5044470070 @default.
• W2143670718 creator A5047373167 @default.
• W2143670718 creator A5048600798 @default.
• W2143670718 creator A5049852915 @default.
• W2143670718 creator A5055945168 @default.
• W2143670718 creator A5061013636 @default.
• W2143670718 date "2015-09-20" @default.
• W2143670718 modified "2023-09-24" @default.
• W2143670718 title "Effect of neostigmine on gastroduodenal motility in patients with suspected gastrointestinal motility disorders" @default.
• W2143670718 cites W1480500461 @default.
• W2143670718 cites W1506289786 @default.
• W2143670718 cites W1557583413 @default.
• W2143670718 cites W1565481374 @default.
• W2143670718 cites W1640278819 @default.
• W2143670718 cites W1761976336 @default.
• W2143670718 cites W1769678725 @default.
• W2143670718 cites W1869504527 @default.
• W2143670718 cites W1967644216 @default.
• W2143670718 cites W1973270602 @default.
• W2143670718 cites W1987999867 @default.
• W2143670718 cites W2013610827 @default.
• W2143670718 cites W2025161884 @default.
• W2143670718 cites W2025530479 @default.
• W2143670718 cites W2026312057 @default.
• W2143670718 cites W2028088566 @default.
• W2143670718 cites W2030407736 @default.
• W2143670718 cites W2031905676 @default.
• W2143670718 cites W2045852609 @default.
• W2143670718 cites W2046201279 @default.
• W2143670718 cites W2046311747 @default.
• W2143670718 cites W2068993423 @default.
• W2143670718 cites W2076909584 @default.
• W2143670718 cites W2096790188 @default.
• W2143670718 cites W2099285210 @default.
• W2143670718 cites W2099590846 @default.
• W2143670718 cites W2100894191 @default.
• W2143670718 cites W2105231848 @default.
• W2143670718 cites W2106647978 @default.
• W2143670718 cites W2122114281 @default.
• W2143670718 cites W2130393732 @default.
• W2143670718 cites W2154089608 @default.
• W2143670718 cites W2158691432 @default.
• W2143670718 cites W2162133024 @default.
• W2143670718 cites W2182493411 @default.
• W2143670718 cites W2259832236 @default.
• W2143670718 cites W2766032561 @default.
• W2143670718 cites W4234384519 @default.
• W2143670718 cites W4255505336 @default.
• W2143670718 cites W84363548 @default.
• W2143670718 doi "https://doi.org/10.1111/nmo.12669" @default.
• W2143670718 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4659742" @default.
• W2143670718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26387781" @default.
• W2143670718 hasPublicationYear "2015" @default.
• W2143670718 type Work @default.
• W2143670718 sameAs 2143670718 @default.
• W2143670718 citedByCount "38" @default.
• W2143670718 countsByYear W21436707182016 @default.
• W2143670718 countsByYear W21436707182017 @default.
• W2143670718 countsByYear W21436707182018 @default.
• W2143670718 countsByYear W21436707182019 @default.
• W2143670718 countsByYear W21436707182020 @default.
• W2143670718 countsByYear W21436707182021 @default.
• W2143670718 countsByYear W21436707182022 @default.
• W2143670718 countsByYear W21436707182023 @default.
• W2143670718 crossrefType "journal-article" @default.
• W2143670718 hasAuthorship W2143670718A5001729912 @default.
• W2143670718 hasAuthorship W2143670718A5029520025 @default.
• W2143670718 hasAuthorship W2143670718A5044470070 @default.
• W2143670718 hasAuthorship W2143670718A5047373167 @default.
• W2143670718 hasAuthorship W2143670718A5048600798 @default.
• W2143670718 hasAuthorship W2143670718A5049852915 @default.
• W2143670718 hasAuthorship W2143670718A5055945168 @default.
• W2143670718 hasAuthorship W2143670718A5061013636 @default.
• W2143670718 hasBestOaLocation W21436707182 @default.
• W2143670718 hasConcept C126322002 @default.
• W2143670718 hasConcept C206813253 @default.
• W2143670718 hasConcept C2776356852 @default.
• W2143670718 hasConcept C2777411258 @default.
• W2143670718 hasConcept C2778271842 @default.
• W2143670718 hasConcept C2778769438 @default.
• W2143670718 hasConcept C2779422922 @default.
• W2143670718 hasConcept C3020479747 @default.
• W2143670718 hasConcept C42219234 @default.
• W2143670718 hasConcept C71924100 @default.
• W2143670718 hasConcept C90924648 @default.
• W2143670718 hasConceptScore W2143670718C126322002 @default.
• W2143670718 hasConceptScore W2143670718C206813253 @default.
• W2143670718 hasConceptScore W2143670718C2776356852 @default.
• W2143670718 hasConceptScore W2143670718C2777411258 @default.
• W2143670718 hasConceptScore W2143670718C2778271842 @default.
• W2143670718 hasConceptScore W2143670718C2778769438 @default.
• W2143670718 hasConceptScore W2143670718C2779422922 @default.
• W2143670718 hasConceptScore W2143670718C3020479747 @default.
• W2143670718 hasConceptScore W2143670718C42219234 @default.

• next