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- W2143752004 abstract "Aim of this study was to present the influence of vertical and horizontal whole-body-vibration with different frequencies on the osteoporotic lumbar spine in the rat animal model. Therefore 75 rats (Sprague Dawley) were bilaterally ovariectomized and 15 rats sham-operated, all at the age of three month. The animals were divided into 6 groups, each consisting 15 rats treated with a different therapy of whole-body-vibration and the non-treated groups Sham and OVX. After developing osteoporosis for 61 days, whole-body-vibration was induced twice a day for 15 minutes on 31 following days with different frequencies (35 Hz vertical, 70 Hz vertical, 35 Hz horizontal, 70 Hz horizontal). After 31 days of WBV the animals were sacrificed by decapitation, the single lumbar vertebrae were prepareted and supplied to the respective tests. The bone mineral density and the share of calcium and phosphate were determined by ashing and flame atomic absorption spectroscopy/photometry on the second lumbar vertebrae. For examination of the biomechanical properties, the fourth lumbar vertebrae was subjected to an axial compression test as entire bone. Information about the bone volume, bone mineral density and the trabecular network could be obtained by analyzing the third lumbar vertebrae with micro-ct. Subsequently the results of the ashing and the micro-ct were correlated with the biomechanical properties to identify the determinants of a stable bone. The results reveal the negative influence of an oestrogen deficiency on the biomechanical properties, the bone mineral density, the bone volume and the thickness of the trabecular bone and the positive effect of the whole-body-vibration as a non-medical treatment of osteoporosis. The animals treated with 35 Hz vertical vibration reached the level of the non-treated healthy animals of the sham-group concerning the biomechanical properties (Fmax, yield load, slope) and the total BMD. The horizontal vibration showed no distinct effect on the examined parameters. The correlation coefficient revealed the dependence of the biomechanical stability to the trabecular thickness, the bone volume and BMD examined by micro-ct. Consequently the data collected with micro-ct can be directly linked to the biomechanical strength and the fracture inclination. In this study the impact and benefits of a vertical 35 Hz WBV on the osteoporotic lumbar spine of the rat was proofed. The confirmation of the results in a large animal model as well as the implementation of clinical studies are objectives for future examinations in order to prove the WBV as a broadly accepted non-medical therapy of osteoporosis." @default.
- W2143752004 created "2016-06-24" @default.
- W2143752004 creator A5079279783 @default.
- W2143752004 date "2022-02-20" @default.
- W2143752004 modified "2023-10-14" @default.
- W2143752004 title "Einfluss der vertikalen und horizontalen Ganzkörpervibration mit verschiedenen Frequenzen auf die Lendenwirbelsäule im Rattentiermodell" @default.
- W2143752004 cites W1597532323 @default.
- W2143752004 cites W162559276 @default.
- W2143752004 cites W173665808 @default.
- W2143752004 cites W179709575 @default.
- W2143752004 cites W1972190722 @default.
- W2143752004 cites W1973888268 @default.
- W2143752004 cites W1973965698 @default.
- W2143752004 cites W1974995152 @default.
- W2143752004 cites W1981874801 @default.
- W2143752004 cites W1982187195 @default.
- W2143752004 cites W1982195212 @default.
- W2143752004 cites W1986906824 @default.
- W2143752004 cites W1991907993 @default.
- W2143752004 cites W1993079074 @default.
- W2143752004 cites W1996926816 @default.
- W2143752004 cites W2003158379 @default.
- W2143752004 cites W2005008336 @default.
- W2143752004 cites W2007206454 @default.
- W2143752004 cites W2008147692 @default.
- W2143752004 cites W2009119794 @default.
- W2143752004 cites W2013724724 @default.
- W2143752004 cites W2013785685 @default.
- W2143752004 cites W2013987973 @default.
- W2143752004 cites W2014725844 @default.
- W2143752004 cites W2015619102 @default.
- W2143752004 cites W2015866089 @default.
- W2143752004 cites W2019693617 @default.
- W2143752004 cites W2019855155 @default.
- W2143752004 cites W2023237068 @default.
- W2143752004 cites W2025199445 @default.
- W2143752004 cites W2027093084 @default.
- W2143752004 cites W2027102778 @default.
- W2143752004 cites W2030264911 @default.
- W2143752004 cites W2033138497 @default.
- W2143752004 cites W2034403497 @default.
- W2143752004 cites W2039038256 @default.
- W2143752004 cites W2041574230 @default.
- W2143752004 cites W2046882160 @default.
- W2143752004 cites W2047219483 @default.
- W2143752004 cites W2048733914 @default.
- W2143752004 cites W2049418136 @default.
- W2143752004 cites W2051277535 @default.
- W2143752004 cites W2052113230 @default.
- W2143752004 cites W2060164580 @default.
- W2143752004 cites W2060794863 @default.
- W2143752004 cites W2062513903 @default.
- W2143752004 cites W2062966761 @default.
- W2143752004 cites W2063048904 @default.
- W2143752004 cites W2068662650 @default.
- W2143752004 cites W2071618370 @default.
- W2143752004 cites W2076019819 @default.
- W2143752004 cites W2076074347 @default.
- W2143752004 cites W2076349290 @default.
- W2143752004 cites W2082801823 @default.
- W2143752004 cites W2087378917 @default.
- W2143752004 cites W2090348823 @default.
- W2143752004 cites W2091312818 @default.
- W2143752004 cites W2096464137 @default.
- W2143752004 cites W2096573414 @default.
- W2143752004 cites W2097619699 @default.
- W2143752004 cites W2107569718 @default.
- W2143752004 cites W2107789045 @default.
- W2143752004 cites W2108063837 @default.
- W2143752004 cites W2110951228 @default.
- W2143752004 cites W2115133477 @default.
- W2143752004 cites W2116384742 @default.
- W2143752004 cites W2116751183 @default.
- W2143752004 cites W2118692723 @default.
- W2143752004 cites W2120171164 @default.
- W2143752004 cites W2120235049 @default.
- W2143752004 cites W2123757980 @default.
- W2143752004 cites W2126113667 @default.
- W2143752004 cites W2129143818 @default.
- W2143752004 cites W2133514604 @default.
- W2143752004 cites W2134403689 @default.
- W2143752004 cites W2135048403 @default.
- W2143752004 cites W2136598250 @default.
- W2143752004 cites W2140470606 @default.
- W2143752004 cites W2141161085 @default.
- W2143752004 cites W2142732756 @default.
- W2143752004 cites W2143145445 @default.
- W2143752004 cites W2145830993 @default.
- W2143752004 cites W2150074402 @default.
- W2143752004 cites W2156331677 @default.
- W2143752004 cites W2169237541 @default.
- W2143752004 cites W2171705946 @default.
- W2143752004 cites W2203608752 @default.
- W2143752004 cites W2463619810 @default.
- W2143752004 cites W2483037354 @default.
- W2143752004 cites W3203441888 @default.
- W2143752004 cites W70539873 @default.
- W2143752004 cites W952837681 @default.
- W2143752004 doi "https://doi.org/10.53846/goediss-4739" @default.
- W2143752004 hasPublicationYear "2022" @default.