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- W2143790403 abstract "RATIONALE: Nasal corticosteroids (NCS) reduce adenoidal size in children with allergic rhinitis. Our objective is to determine the effects of NCS upon adenoidal hypertrophy in children with non-allergic rhinitis. METHODS: Records of children with non-allergic rhinitis were reviewed. Those with lateral neck x-rays documenting adenoidal hypertrophy were the study population. Subjects were divided into group A, comprising of patients treated with NCS, and group B who received no NCS. The outcomes of treatment were compared. End points included symptomatic improvement, radiological adenoidal reduction and need for surgical resection. Symptoms assessed included snoring, mouth breathing and periods of apnea or restlessness during sleep. RESULTS: 80 patients aged 9 months to 17 years (mean 4 years) fulfilled the entrance criteria. 42/80 (53%) were male. 58/80 (73%) were treated with NCS (group A), and 22/80 received no NCS (group B). Mean duration of therapy was eight months. 32/58 (55%) in group A improved either symptomatically or radiologically compared to 6/22 (27%) in group B (p=0.03). Adenoidectomies were ultimately performed in 21/58 (36%) of group A compared to 10/22 (45%) in group B (p=0.44). Risk factors in group A non-responders were examined. Age, tobacco smoke exposure, presence of sinusitis and history of gastroesophageal disease (GERD) were similar in the responders and non-responders. However, 9/16 (56%) in the responder group received treatment for GERD, compared to 3/14 (21%) in the non-responder group (p=0.05). CONCLUSIONS: This study suggests that NCS significantly improve adenoidal hypertrophy in children with non-allergic rhinitis. Untreated GERD may result in apparent non-responsiveness to nasal steroids." @default.
- W2143790403 created "2016-06-24" @default.
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- W2143790403 date "2006-02-01" @default.
- W2143790403 modified "2023-09-24" @default.
- W2143790403 title "Effect of Nasal Corticosteroids on Adenoidal Hypertrophy in Children with Non-Allergic Rhinitis" @default.
- W2143790403 doi "https://doi.org/10.1016/j.jaci.2005.12.662" @default.
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