FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143809989> ?p ?o ?g. }

• W2143809989 endingPage "2095" @default.
• W2143809989 startingPage "2087" @default.
• W2143809989 abstract "IL-6 and TNF alpha secretion is increased by sleep loss or restriction. IL-6 secretion progressively increases with age, yet its association with decreased quality and quantity of sleep in old adults is unknown. This study examined the alteration of 24-h secretory pattern of IL-6, TNF alpha, and cortisol in 15 young and 13 old normal sleepers who were recorded in the sleep laboratory for four consecutive nights. Serial 24-h plasma measures of IL-6, TNF alpha, and cortisol were obtained during the fourth day, and daytime sleepiness was assessed with the multiple sleep latency test. Old adults, compared with young subjects, slept poorly at night (wake time and percentage stage 1 sleep were increased, whereas their percentage slow wave sleep and percentage sleep time were decreased, P < 0.05). Accordingly, their daytime sleep latency was longer than in young adults (P < 0.05). The mean 24-h IL-6 and cortisol levels were significantly higher in old than young adults (P < 0.05). In both groups, IL-6 and cortisol plasma concentrations were positively associated with total wake time, with a stronger association of IL-6 and cortisol with total wake time in the older individuals (P < 0.05); their combined effect was additive. IL-6 had a negative association with rapid eye movement (REM) sleep only in the young (P < 0.05), but cortisol was associated negatively with REM sleep both in the young and old, with a stronger effect in the young. We conclude that in healthy adults, age-related alterations in nocturnal wake time and daytime sleepiness are associated with elevations of both plasma IL-6 and cortisol concentrations, but REM sleep decline with age is primarily associated with cortisol increases." @default.
• W2143809989 created "2016-06-24" @default.
• W2143809989 creator A5000066478 @default.
• W2143809989 creator A5001597425 @default.
• W2143809989 creator A5026427094 @default.
• W2143809989 creator A5036701871 @default.
• W2143809989 creator A5046164327 @default.
• W2143809989 creator A5051721081 @default.
• W2143809989 creator A5059575944 @default.
• W2143809989 creator A5073483206 @default.
• W2143809989 date "2003-05-01" @default.
• W2143809989 modified "2023-10-15" @default.
• W2143809989 title "Impaired Nighttime Sleep in Healthy Old<i>Versus</i>Young Adults Is Associated with Elevated Plasma Interleukin-6 and Cortisol Levels: Physiologic and Therapeutic Implications" @default.
• W2143809989 cites W1521227715 @default.
• W2143809989 cites W1529535966 @default.
• W2143809989 cites W1715223110 @default.
• W2143809989 cites W1880976932 @default.
• W2143809989 cites W1965212068 @default.
• W2143809989 cites W1975319022 @default.
• W2143809989 cites W1980615352 @default.
• W2143809989 cites W1985953874 @default.
• W2143809989 cites W1999790218 @default.
• W2143809989 cites W2015417570 @default.
• W2143809989 cites W2031570679 @default.
• W2143809989 cites W2033916720 @default.
• W2143809989 cites W2035490031 @default.
• W2143809989 cites W2037675204 @default.
• W2143809989 cites W2039628081 @default.
• W2143809989 cites W2052495561 @default.
• W2143809989 cites W2056763517 @default.
• W2143809989 cites W2069272625 @default.
• W2143809989 cites W2071937025 @default.
• W2143809989 cites W2084292135 @default.
• W2143809989 cites W2090140151 @default.
• W2143809989 cites W2092528638 @default.
• W2143809989 cites W2106749899 @default.
• W2143809989 cites W2118424059 @default.
• W2143809989 cites W2128979836 @default.
• W2143809989 cites W2137708344 @default.
• W2143809989 cites W2155847222 @default.
• W2143809989 cites W2155954337 @default.
• W2143809989 cites W2159458171 @default.
• W2143809989 cites W2320349682 @default.
• W2143809989 cites W3022302886 @default.
• W2143809989 cites W3196838194 @default.
• W2143809989 cites W346174202 @default.
• W2143809989 cites W2056930167 @default.
• W2143809989 cites W2130799477 @default.
• W2143809989 doi "https://doi.org/10.1210/jc.2002-021176" @default.
• W2143809989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12727959" @default.
• W2143809989 hasPublicationYear "2003" @default.
• W2143809989 type Work @default.
• W2143809989 sameAs 2143809989 @default.
• W2143809989 citedByCount "220" @default.
• W2143809989 countsByYear W21438099892012 @default.
• W2143809989 countsByYear W21438099892013 @default.
• W2143809989 countsByYear W21438099892014 @default.
• W2143809989 countsByYear W21438099892015 @default.
• W2143809989 countsByYear W21438099892016 @default.
• W2143809989 countsByYear W21438099892017 @default.
• W2143809989 countsByYear W21438099892018 @default.
• W2143809989 countsByYear W21438099892019 @default.
• W2143809989 countsByYear W21438099892020 @default.
• W2143809989 countsByYear W21438099892021 @default.
• W2143809989 countsByYear W21438099892022 @default.
• W2143809989 countsByYear W21438099892023 @default.
• W2143809989 crossrefType "journal-article" @default.
• W2143809989 hasAuthorship W2143809989A5000066478 @default.
• W2143809989 hasAuthorship W2143809989A5001597425 @default.
• W2143809989 hasAuthorship W2143809989A5026427094 @default.
• W2143809989 hasAuthorship W2143809989A5036701871 @default.
• W2143809989 hasAuthorship W2143809989A5046164327 @default.
• W2143809989 hasAuthorship W2143809989A5051721081 @default.
• W2143809989 hasAuthorship W2143809989A5059575944 @default.
• W2143809989 hasAuthorship W2143809989A5073483206 @default.
• W2143809989 hasBestOaLocation W21438099891 @default.
• W2143809989 hasConcept C111919701 @default.
• W2143809989 hasConcept C118552586 @default.
• W2143809989 hasConcept C121446783 @default.
• W2143809989 hasConcept C126322002 @default.
• W2143809989 hasConcept C134018914 @default.
• W2143809989 hasConcept C15744967 @default.
• W2143809989 hasConcept C205545832 @default.
• W2143809989 hasConcept C2775841894 @default.
• W2143809989 hasConcept C2778205975 @default.
• W2143809989 hasConcept C2778329153 @default.
• W2143809989 hasConcept C2778709874 @default.
• W2143809989 hasConcept C2780937657 @default.
• W2143809989 hasConcept C2781053850 @default.
• W2143809989 hasConcept C2781210498 @default.
• W2143809989 hasConcept C2781326671 @default.
• W2143809989 hasConcept C2910364982 @default.
• W2143809989 hasConcept C41008148 @default.
• W2143809989 hasConcept C63759246 @default.
• W2143809989 hasConcept C71924100 @default.
• W2143809989 hasConceptScore W2143809989C111919701 @default.
• W2143809989 hasConceptScore W2143809989C118552586 @default.
• W2143809989 hasConceptScore W2143809989C121446783 @default.

• next