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- W2143877545 abstract "A novel and efficient method has been developed for the synthesis of a series of 3,4-dihydroquinazoline-2(1H)-thione derivatives in aqueous organic solvent starting from 3-(2-aminophenyl)acrylates with isothiocyanates via a tandem intermolecular nucleophilic addition/intramolecular Michael addition reaction under mild conditions. A broad substrate scope has been demonstrated, which shows wide functional group tolerance and chemical specialization. The efficiency of the methodology could make this process available on gram-scale." @default.
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- W2143877545 date "2014-05-26" @default.
- W2143877545 modified "2023-09-26" @default.
- W2143877545 title "A Straightforward One-Pot Synthesis of 3,4-Dihydroquinazoline-2(1H)-thione Derivatives in Aqueous Organic Solvent" @default.
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- W2143877545 doi "https://doi.org/10.1002/jhet.2022" @default.
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