FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143895879> ?p ?o ?g. }

• W2143895879 abstract "Throughout the nervous system, neurons integrate high-dimensional input streams and transform them into an output of their own. This integration of incoming signals involves filtering processes and complex non-linear operations. The shapes of these filters and non-linearities determine the computational features of single neurons and their functional roles within larger networks. A detailed characterization of signal integration is thus a central ingredient to understanding information processing in neural circuits. Conventional methods for measuring single-neuron response properties, such as reverse correlation, however, are often limited by the implicit assumption that stimulus integration occurs in a linear fashion. Here, we review a conceptual and experimental alternative that is based on exploring the space of those sensory stimuli that result in the same neural output. As demonstrated by recent results in the auditory and visual system, such iso-response stimuli can be used to identify the non-linearities relevant for stimulus integration, disentangle consecutive neural processing steps, and determine their characteristics with unprecedented precision. Automated closed-loop experiments are crucial for this advance, allowing rapid search strategies for identifying iso-response stimuli during experiments. Prime targets for the method are feed-forward neural signaling chains in sensory systems, but the method has also been successfully applied to feedback systems. Depending on the specific question, iso-response may refer to a predefined firing rate, single-spike probability, first-spike latency, or other output measures. Examples from different studies show that substantial progress in understanding neural dynamics and coding can be achieved once rapid online data analysis and stimulus generation, adaptive sampling, and computational modeling are tightly integrated into experiments." @default.
• W2143895879 created "2016-06-24" @default.
• W2143895879 creator A5029489554 @default.
• W2143895879 creator A5086835913 @default.
• W2143895879 date "2012-01-01" @default.
• W2143895879 modified "2023-10-18" @default.
• W2143895879 title "The iso-response method: measuring neuronal stimulus integration with closed-loop experiments" @default.
• W2143895879 cites W1482296698 @default.
• W2143895879 cites W1509369178 @default.
• W2143895879 cites W1510003352 @default.
• W2143895879 cites W1519946308 @default.
• W2143895879 cites W1522430845 @default.
• W2143895879 cites W1522975959 @default.
• W2143895879 cites W1538619419 @default.
• W2143895879 cites W1592082209 @default.
• W2143895879 cites W1627384048 @default.
• W2143895879 cites W1630119268 @default.
• W2143895879 cites W1956321781 @default.
• W2143895879 cites W1964309659 @default.
• W2143895879 cites W1970630433 @default.
• W2143895879 cites W1980141249 @default.
• W2143895879 cites W1988849438 @default.
• W2143895879 cites W1989602986 @default.
• W2143895879 cites W1992156523 @default.
• W2143895879 cites W1992646289 @default.
• W2143895879 cites W2000509838 @default.
• W2143895879 cites W2000674655 @default.
• W2143895879 cites W2011860702 @default.
• W2143895879 cites W2012920191 @default.
• W2143895879 cites W2013136684 @default.
• W2143895879 cites W2019723923 @default.
• W2143895879 cites W2025988651 @default.
• W2143895879 cites W2027446612 @default.
• W2143895879 cites W2034569242 @default.
• W2143895879 cites W2035108601 @default.
• W2143895879 cites W2043819488 @default.
• W2143895879 cites W2043947202 @default.
• W2143895879 cites W2046064811 @default.
• W2143895879 cites W2047002718 @default.
• W2143895879 cites W2060831891 @default.
• W2143895879 cites W2066172985 @default.
• W2143895879 cites W2081729933 @default.
• W2143895879 cites W2095868797 @default.
• W2143895879 cites W2099616257 @default.
• W2143895879 cites W2108992228 @default.
• W2143895879 cites W2109634313 @default.
• W2143895879 cites W2112455917 @default.
• W2143895879 cites W2113335883 @default.
• W2143895879 cites W2114185957 @default.
• W2143895879 cites W2119533571 @default.
• W2143895879 cites W2122718953 @default.
• W2143895879 cites W2125498357 @default.
• W2143895879 cites W2125617977 @default.
• W2143895879 cites W2125988384 @default.
• W2143895879 cites W2129963552 @default.
• W2143895879 cites W2131220353 @default.
• W2143895879 cites W2132245232 @default.
• W2143895879 cites W2135488337 @default.
• W2143895879 cites W2136104104 @default.
• W2143895879 cites W2142695991 @default.
• W2143895879 cites W2145268430 @default.
• W2143895879 cites W2155443738 @default.
• W2143895879 cites W2159217888 @default.
• W2143895879 cites W2159343681 @default.
• W2143895879 cites W2162904740 @default.
• W2143895879 cites W2166635906 @default.
• W2143895879 cites W2168434104 @default.
• W2143895879 cites W2169720294 @default.
• W2143895879 cites W2171406132 @default.
• W2143895879 cites W2287110578 @default.
• W2143895879 cites W2293818804 @default.
• W2143895879 cites W2341283081 @default.
• W2143895879 cites W2540095582 @default.
• W2143895879 cites W2616287174 @default.
• W2143895879 doi "https://doi.org/10.3389/fncir.2012.00104" @default.
• W2143895879 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3525953" @default.
• W2143895879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23267315" @default.
• W2143895879 hasPublicationYear "2012" @default.
• W2143895879 type Work @default.
• W2143895879 sameAs 2143895879 @default.
• W2143895879 citedByCount "12" @default.
• W2143895879 countsByYear W21438958792014 @default.
• W2143895879 countsByYear W21438958792016 @default.
• W2143895879 countsByYear W21438958792018 @default.
• W2143895879 countsByYear W21438958792019 @default.
• W2143895879 countsByYear W21438958792020 @default.
• W2143895879 countsByYear W21438958792021 @default.
• W2143895879 countsByYear W21438958792022 @default.
• W2143895879 crossrefType "journal-article" @default.
• W2143895879 hasAuthorship W2143895879A5029489554 @default.
• W2143895879 hasAuthorship W2143895879A5086835913 @default.
• W2143895879 hasBestOaLocation W21438958791 @default.
• W2143895879 hasConcept C154945302 @default.
• W2143895879 hasConcept C15744967 @default.
• W2143895879 hasConcept C169760540 @default.
• W2143895879 hasConcept C2779918689 @default.
• W2143895879 hasConcept C41008148 @default.
• W2143895879 hasConcept C50644808 @default.
• W2143895879 hasConcept C542102704 @default.
• W2143895879 hasConcept C87868495 @default.

• next