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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143910807> ?p ?o ?g. }

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• W2143910807 abstract "Our objective was to compare the sublingual administration and the vaginal administration of misoprostol for cervical priming before first-trimester surgical abortion.We used an open, multicenter, randomized trial.We conducted the study in four clinics (in Valencia, Castelló, Murcia and Murcia Capital) in Spain.A total of 1424 healthy pregnant women with amenorrhea of <or=84 days who voluntarily decided to terminate their pregnancy participated in the study.Women were randomly assigned to receive a single dose of 400 microg of misoprostol either sublingually or vaginally 1-3 h before aspiration.The outcome measures assessed were cervical dilation before surgery and surgical time needed for aspiration. The incidence of side effects, such as nausea, vomiting, diarrhea, fever/chills and paresthesia, was evaluated.The mean cervical dilation achieved was 6.8+/-0.8 and 6.7+/-0.9 mm for the sublingual and vaginal groups, respectively. The mean surgical time was 7.0+/-2.8 and 7.4+/-2.5 min for the sublingual and vaginal groups, respectively. Nausea, vomiting and diarrhea were more frequent in the sublingual group.Both regimens had equal efficacy; however, the sublingual route caused more side effects." @default.
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• W2143910807 date "2006-10-01" @default.
• W2143910807 modified "2023-09-27" @default.
• W2143910807 title "Sublingual versus vaginal misoprostol (400 μg) for cervical priming in first-trimester abortion: a randomized trial" @default.
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• W2143910807 doi "https://doi.org/10.1016/j.contraception.2006.03.031" @default.
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