FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143959240> ?p ?o ?g. }

• W2143959240 endingPage "75" @default.
• W2143959240 startingPage "68" @default.
• W2143959240 abstract "Declining testosterone levels in elderly men are thought to underlie many of the symptoms and diseases of aging; however, studies demonstrating associations of low testosterone with clinical outcomes are few.The objective of the study was to examine the association of endogenous testosterone levels with mortality in older community-dwelling men.This was a prospective, population-based study of 794 men, aged 50-91 (median 73.6) yr who had serum testosterone measurements at baseline (1984-1987) and were followed for mortality through July 2004.All-cause mortality by serum testosterone level was measured.During an average 11.8-yr follow-up, 538 deaths occurred. Men whose total testosterone levels were in the lowest quartile (<241 ng/dl) were 40% [hazards ratio (HR) 1.40; 95% confidence interval (CI) 1.14-1.71] more likely to die than those with higher levels, independent of age, adiposity, and lifestyle. Additional adjustment for health status markers, lipids, lipoproteins, blood pressure, glycemia, adipocytokines, and estradiol levels had minimal effect on results. The low testosterone-mortality association was also independent of the metabolic syndrome, diabetes, and prevalent cardiovascular disease but was attenuated by adjustment for IL-6 and C-reactive protein. In cause-specific analyses, low testosterone predicted increased risk of cardiovascular (HR 1.38; 95% CI 1.02-1.85) and respiratory disease (HR 2.29; 95% CI 1.25-4.20) mortality but was not significantly related to cancer death (HR 1.34; 95% CI 0.89-2.00). Results were similar for bioavailable testosterone.Testosterone insufficiency in older men is associated with increased risk of death over the following 20 yr, independent of multiple risk factors and several preexisting health conditions." @default.
• W2143959240 created "2016-06-24" @default.
• W2143959240 creator A5020802111 @default.
• W2143959240 creator A5084002246 @default.
• W2143959240 creator A5086882609 @default.
• W2143959240 date "2008-01-01" @default.
• W2143959240 modified "2023-10-18" @default.
• W2143959240 title "Low Serum Testosterone and Mortality in Older Men" @default.
• W2143959240 cites W128831921 @default.
• W2143959240 cites W1922980005 @default.
• W2143959240 cites W1963561957 @default.
• W2143959240 cites W1976746229 @default.
• W2143959240 cites W1977417329 @default.
• W2143959240 cites W2028647952 @default.
• W2143959240 cites W2031439281 @default.
• W2143959240 cites W2033929057 @default.
• W2143959240 cites W2042336125 @default.
• W2143959240 cites W2068066490 @default.
• W2143959240 cites W2070937649 @default.
• W2143959240 cites W2076426902 @default.
• W2143959240 cites W2082448317 @default.
• W2143959240 cites W2084691633 @default.
• W2143959240 cites W2096861659 @default.
• W2143959240 cites W2100145402 @default.
• W2143959240 cites W2102240367 @default.
• W2143959240 cites W2122895485 @default.
• W2143959240 cites W2123393430 @default.
• W2143959240 cites W2127454781 @default.
• W2143959240 cites W2132060900 @default.
• W2143959240 cites W2139893960 @default.
• W2143959240 cites W2146511410 @default.
• W2143959240 cites W2149914864 @default.
• W2143959240 cites W2155165820 @default.
• W2143959240 cites W2162151423 @default.
• W2143959240 cites W2165312445 @default.
• W2143959240 cites W2165913105 @default.
• W2143959240 cites W2165977461 @default.
• W2143959240 cites W2185055660 @default.
• W2143959240 cites W3036378166 @default.
• W2143959240 doi "https://doi.org/10.1210/jc.2007-1792" @default.
• W2143959240 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2190742" @default.
• W2143959240 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17911176" @default.
• W2143959240 hasPublicationYear "2008" @default.
• W2143959240 type Work @default.
• W2143959240 sameAs 2143959240 @default.
• W2143959240 citedByCount "716" @default.
• W2143959240 countsByYear W21439592402012 @default.
• W2143959240 countsByYear W21439592402013 @default.
• W2143959240 countsByYear W21439592402014 @default.
• W2143959240 countsByYear W21439592402015 @default.
• W2143959240 countsByYear W21439592402016 @default.
• W2143959240 countsByYear W21439592402017 @default.
• W2143959240 countsByYear W21439592402018 @default.
• W2143959240 countsByYear W21439592402019 @default.
• W2143959240 countsByYear W21439592402020 @default.
• W2143959240 countsByYear W21439592402021 @default.
• W2143959240 countsByYear W21439592402022 @default.
• W2143959240 countsByYear W21439592402023 @default.
• W2143959240 crossrefType "journal-article" @default.
• W2143959240 hasAuthorship W2143959240A5020802111 @default.
• W2143959240 hasAuthorship W2143959240A5084002246 @default.
• W2143959240 hasAuthorship W2143959240A5086882609 @default.
• W2143959240 hasBestOaLocation W21439592401 @default.
• W2143959240 hasConcept C126322002 @default.
• W2143959240 hasConcept C134018914 @default.
• W2143959240 hasConcept C188816634 @default.
• W2143959240 hasConcept C2779279991 @default.
• W2143959240 hasConcept C2908647359 @default.
• W2143959240 hasConcept C42407357 @default.
• W2143959240 hasConcept C44249647 @default.
• W2143959240 hasConcept C555293320 @default.
• W2143959240 hasConcept C68443243 @default.
• W2143959240 hasConcept C71924100 @default.
• W2143959240 hasConcept C99454951 @default.
• W2143959240 hasConceptScore W2143959240C126322002 @default.
• W2143959240 hasConceptScore W2143959240C134018914 @default.
• W2143959240 hasConceptScore W2143959240C188816634 @default.
• W2143959240 hasConceptScore W2143959240C2779279991 @default.
• W2143959240 hasConceptScore W2143959240C2908647359 @default.
• W2143959240 hasConceptScore W2143959240C42407357 @default.
• W2143959240 hasConceptScore W2143959240C44249647 @default.
• W2143959240 hasConceptScore W2143959240C555293320 @default.
• W2143959240 hasConceptScore W2143959240C68443243 @default.
• W2143959240 hasConceptScore W2143959240C71924100 @default.
• W2143959240 hasConceptScore W2143959240C99454951 @default.
• W2143959240 hasIssue "1" @default.
• W2143959240 hasLocation W21439592401 @default.
• W2143959240 hasLocation W21439592402 @default.
• W2143959240 hasLocation W21439592403 @default.
• W2143959240 hasLocation W21439592404 @default.
• W2143959240 hasOpenAccess W2143959240 @default.
• W2143959240 hasPrimaryLocation W21439592401 @default.
• W2143959240 hasRelatedWork W1988486434 @default.
• W2143959240 hasRelatedWork W1998113603 @default.
• W2143959240 hasRelatedWork W1999611386 @default.
• W2143959240 hasRelatedWork W1999831221 @default.
• W2143959240 hasRelatedWork W2026882188 @default.
• W2143959240 hasRelatedWork W2027237635 @default.

• next