FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143969839> ?p ?o ?g. }

• W2143969839 endingPage "7" @default.
• W2143969839 startingPage "1" @default.
• W2143969839 abstract "The aim of this research was to evaluate the potential of the nanospray drier as a novel apparatus for the manufacturing of a dry powder for inhalation containing ketoprofen lysinate, a nonsteroidal anti-inflammatory drug able to control the inflammation in cystic fibrosis patients. We produced several ketoprofen lysinate and leucine powder batches by means of nanospray dryer, studying the influence of process parameters on yield, particle properties (size distribution and morphology), and, mainly, aerodynamic properties of powders. Micronized particles were prepared from different hydroalcoholic solutions (alcohol content from 0 to 30% v/v) using ketoprofen in its lysine salt form and leucine as dispersibility enhancer in different ratios (from 5 to 15% w/w) with a total solid concentration ranging from 1 to 7% w/v. Results indicated that the spray head equipped with a 7 µm nozzle produced powders too big to be inhaled. The reduction of nozzle size from 7 to 4 µm led to smaller particles suitable for inhalation but, at the same time, caused a dramatic increase in process time. The selection of process variables, together with the nozzle pretreatment with a surfactant solution, allowed us to obtain a free flowing powder with satisfying aerosol performance, confirming the usefulness of the nanospray drier in the production of powder for inhalation." @default.
• W2143969839 created "2016-06-24" @default.
• W2143969839 creator A5005669717 @default.
• W2143969839 creator A5025363235 @default.
• W2143969839 creator A5051423176 @default.
• W2143969839 creator A5075775057 @default.
• W2143969839 creator A5089201408 @default.
• W2143969839 creator A5091102946 @default.
• W2143969839 date "2014-01-01" @default.
• W2143969839 modified "2023-09-23" @default.
• W2143969839 title "Nanospray Drying as a Novel Technique for the Manufacturing of Inhalable NSAID Powders" @default.
• W2143969839 cites W1978062897 @default.
• W2143969839 cites W1986421799 @default.
• W2143969839 cites W1987537515 @default.
• W2143969839 cites W1991433186 @default.
• W2143969839 cites W1997576665 @default.
• W2143969839 cites W2000175714 @default.
• W2143969839 cites W2000619516 @default.
• W2143969839 cites W2012506930 @default.
• W2143969839 cites W2014184580 @default.
• W2143969839 cites W2033755583 @default.
• W2143969839 cites W2041981203 @default.
• W2143969839 cites W2074983458 @default.
• W2143969839 cites W2075515726 @default.
• W2143969839 cites W2093543829 @default.
• W2143969839 cites W2107839728 @default.
• W2143969839 cites W2118476975 @default.
• W2143969839 cites W2123166078 @default.
• W2143969839 cites W2132099356 @default.
• W2143969839 cites W2154064195 @default.
• W2143969839 cites W2164266773 @default.
• W2143969839 doi "https://doi.org/10.1155/2014/838410" @default.
• W2143969839 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4279258" @default.
• W2143969839 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25580462" @default.
• W2143969839 hasPublicationYear "2014" @default.
• W2143969839 type Work @default.
• W2143969839 sameAs 2143969839 @default.
• W2143969839 citedByCount "5" @default.
• W2143969839 countsByYear W21439698392015 @default.
• W2143969839 countsByYear W21439698392016 @default.
• W2143969839 countsByYear W21439698392021 @default.
• W2143969839 countsByYear W21439698392022 @default.
• W2143969839 crossrefType "journal-article" @default.
• W2143969839 hasAuthorship W2143969839A5005669717 @default.
• W2143969839 hasAuthorship W2143969839A5025363235 @default.
• W2143969839 hasAuthorship W2143969839A5051423176 @default.
• W2143969839 hasAuthorship W2143969839A5075775057 @default.
• W2143969839 hasAuthorship W2143969839A5089201408 @default.
• W2143969839 hasAuthorship W2143969839A5091102946 @default.
• W2143969839 hasBestOaLocation W21439698391 @default.
• W2143969839 hasConcept C121332964 @default.
• W2143969839 hasConcept C127413603 @default.
• W2143969839 hasConcept C147789679 @default.
• W2143969839 hasConcept C185592680 @default.
• W2143969839 hasConcept C187530423 @default.
• W2143969839 hasConcept C192562407 @default.
• W2143969839 hasConcept C2776954882 @default.
• W2143969839 hasConcept C2779587474 @default.
• W2143969839 hasConcept C2780744026 @default.
• W2143969839 hasConcept C42219234 @default.
• W2143969839 hasConcept C42360764 @default.
• W2143969839 hasConcept C43617362 @default.
• W2143969839 hasConcept C56200935 @default.
• W2143969839 hasConcept C71924100 @default.
• W2143969839 hasConcept C97355855 @default.
• W2143969839 hasConceptScore W2143969839C121332964 @default.
• W2143969839 hasConceptScore W2143969839C127413603 @default.
• W2143969839 hasConceptScore W2143969839C147789679 @default.
• W2143969839 hasConceptScore W2143969839C185592680 @default.
• W2143969839 hasConceptScore W2143969839C187530423 @default.
• W2143969839 hasConceptScore W2143969839C192562407 @default.
• W2143969839 hasConceptScore W2143969839C2776954882 @default.
• W2143969839 hasConceptScore W2143969839C2779587474 @default.
• W2143969839 hasConceptScore W2143969839C2780744026 @default.
• W2143969839 hasConceptScore W2143969839C42219234 @default.
• W2143969839 hasConceptScore W2143969839C42360764 @default.
• W2143969839 hasConceptScore W2143969839C43617362 @default.
• W2143969839 hasConceptScore W2143969839C56200935 @default.
• W2143969839 hasConceptScore W2143969839C71924100 @default.
• W2143969839 hasConceptScore W2143969839C97355855 @default.
• W2143969839 hasLocation W21439698391 @default.
• W2143969839 hasLocation W21439698392 @default.
• W2143969839 hasLocation W21439698393 @default.
• W2143969839 hasLocation W21439698394 @default.
• W2143969839 hasOpenAccess W2143969839 @default.
• W2143969839 hasPrimaryLocation W21439698391 @default.
• W2143969839 hasRelatedWork W1940085777 @default.
• W2143969839 hasRelatedWork W1983406611 @default.
• W2143969839 hasRelatedWork W2143706141 @default.
• W2143969839 hasRelatedWork W2143969839 @default.
• W2143969839 hasRelatedWork W2360820328 @default.
• W2143969839 hasRelatedWork W2519841082 @default.
• W2143969839 hasRelatedWork W2795572942 @default.
• W2143969839 hasRelatedWork W2899084033 @default.
• W2143969839 hasRelatedWork W2946059884 @default.
• W2143969839 hasRelatedWork W2992650423 @default.
• W2143969839 hasVolume "2014" @default.
• W2143969839 isParatext "false" @default.

• next