FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143996952> ?p ?o ?g. }

• W2143996952 endingPage "134" @default.
• W2143996952 startingPage "134" @default.
• W2143996952 abstract "Porphyromonas gingivalis is a major etiological agent of chronic periodontitis. The aim of this study was to examine the species specificity, surface exposure, protein expression, immunogenicity, and participation in biofilm formation of the P. gingivalis heme-binding protein HmuY. HmuY is a unique protein of P. gingivalis since only low amino-acid sequence homology has been found to proteins encoded in other species. It is exposed on the cell surface and highly abundant in the outer membrane of the cell, in outer-membrane vesicles, and is released into culture medium in a soluble form. The protein is produced constitutively at low levels in bacteria grown under high-iron/heme conditions and at higher levels in bacteria growing under the low-iron/heme conditions typical of dental plaque. HmuY is immunogenic and elicits high IgG antibody titers in rabbits. It is also engaged in homotypic biofilm formation by P. gingivalis. Anti-HmuY antibodies exhibit inhibitory activity against P. gingivalis growth and biofilm formation. Here it is demonstrated that HmuY may play a significant role not only in heme acquisition, but also in biofilm accumulation on abiotic surfaces. The data also suggest that HmuY, as a surface-exposed protein, would be available for recognition by the immune response during chronic periodontitis and the production of anti-HmuY antibodies may inhibit biofilm formation." @default.
• W2143996952 created "2016-06-24" @default.
• W2143996952 creator A5011897079 @default.
• W2143996952 creator A5064033477 @default.
• W2143996952 creator A5078768895 @default.
• W2143996952 creator A5082389527 @default.
• W2143996952 date "2010-01-01" @default.
• W2143996952 modified "2023-09-26" @default.
• W2143996952 title "Species specificity, surface exposure, protein expression, immunogenicity, and participation in biofilm formation of Porphyromonas gingivalis HmuY" @default.
• W2143996952 cites W1844387272 @default.
• W2143996952 cites W1970063271 @default.
• W2143996952 cites W1979135961 @default.
• W2143996952 cites W1981277690 @default.
• W2143996952 cites W2009735382 @default.
• W2143996952 cites W2014118123 @default.
• W2143996952 cites W2027384372 @default.
• W2143996952 cites W2027484984 @default.
• W2143996952 cites W2028635293 @default.
• W2143996952 cites W2041089815 @default.
• W2143996952 cites W2044076477 @default.
• W2143996952 cites W2048882097 @default.
• W2143996952 cites W2051582658 @default.
• W2143996952 cites W2057081312 @default.
• W2143996952 cites W2057389581 @default.
• W2143996952 cites W2060182219 @default.
• W2143996952 cites W2065864880 @default.
• W2143996952 cites W2071784720 @default.
• W2143996952 cites W2073429226 @default.
• W2143996952 cites W2077124327 @default.
• W2143996952 cites W2078241556 @default.
• W2143996952 cites W2087091587 @default.
• W2143996952 cites W2097706568 @default.
• W2143996952 cites W2102305776 @default.
• W2143996952 cites W2103222461 @default.
• W2143996952 cites W2103584121 @default.
• W2143996952 cites W2104201539 @default.
• W2143996952 cites W2112108373 @default.
• W2143996952 cites W2117688828 @default.
• W2143996952 cites W2119158447 @default.
• W2143996952 cites W2121491059 @default.
• W2143996952 cites W2121893750 @default.
• W2143996952 cites W2123581197 @default.
• W2143996952 cites W2126470914 @default.
• W2143996952 cites W2131778683 @default.
• W2143996952 cites W2131952844 @default.
• W2143996952 cites W2133993854 @default.
• W2143996952 cites W2134964172 @default.
• W2143996952 cites W2137015675 @default.
• W2143996952 cites W2144440398 @default.
• W2143996952 cites W2148103346 @default.
• W2143996952 cites W2148945900 @default.
• W2143996952 cites W2150260980 @default.
• W2143996952 cites W2151687098 @default.
• W2143996952 cites W2157107389 @default.
• W2143996952 cites W2158714788 @default.
• W2143996952 cites W2165984704 @default.
• W2143996952 cites W2167491944 @default.
• W2143996952 doi "https://doi.org/10.1186/1471-2180-10-134" @default.
• W2143996952 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2873494" @default.
• W2143996952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20438645" @default.
• W2143996952 hasPublicationYear "2010" @default.
• W2143996952 type Work @default.
• W2143996952 sameAs 2143996952 @default.
• W2143996952 citedByCount "62" @default.
• W2143996952 countsByYear W21439969522012 @default.
• W2143996952 countsByYear W21439969522013 @default.
• W2143996952 countsByYear W21439969522014 @default.
• W2143996952 countsByYear W21439969522015 @default.
• W2143996952 countsByYear W21439969522016 @default.
• W2143996952 countsByYear W21439969522017 @default.
• W2143996952 countsByYear W21439969522018 @default.
• W2143996952 countsByYear W21439969522019 @default.
• W2143996952 countsByYear W21439969522020 @default.
• W2143996952 countsByYear W21439969522021 @default.
• W2143996952 countsByYear W21439969522022 @default.
• W2143996952 countsByYear W21439969522023 @default.
• W2143996952 crossrefType "journal-article" @default.
• W2143996952 hasAuthorship W2143996952A5011897079 @default.
• W2143996952 hasAuthorship W2143996952A5064033477 @default.
• W2143996952 hasAuthorship W2143996952A5078768895 @default.
• W2143996952 hasAuthorship W2143996952A5082389527 @default.
• W2143996952 hasBestOaLocation W21439969521 @default.
• W2143996952 hasConcept C104317684 @default.
• W2143996952 hasConcept C126322002 @default.
• W2143996952 hasConcept C146587185 @default.
• W2143996952 hasConcept C159654299 @default.
• W2143996952 hasConcept C181199279 @default.
• W2143996952 hasConcept C203014093 @default.
• W2143996952 hasConcept C2776217839 @default.
• W2143996952 hasConcept C2776357993 @default.
• W2143996952 hasConcept C2777349128 @default.
• W2143996952 hasConcept C2779337755 @default.
• W2143996952 hasConcept C2780183776 @default.
• W2143996952 hasConcept C2780385504 @default.
• W2143996952 hasConcept C2780868878 @default.
• W2143996952 hasConcept C523546767 @default.
• W2143996952 hasConcept C54355233 @default.
• W2143996952 hasConcept C547475151 @default.

• next