Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144029319> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2144029319 endingPage "890" @default.
- W2144029319 startingPage "883" @default.
- W2144029319 abstract "Mathematical models of the evolution of drug resistance in infectious diseases are predominantly concentrated in three main areas: antimalarial, antibiotic and anthelmintic resistance. There appears to be little or no cross-reference between them. This literature was examined to identify factors that influence the evolution of drug resistance irrespective of the species and drug under study. The aim is to provide non-technical readers with a basic qualitative understanding of the issues and pitfalls involved in designing drug treatment regimens to minimize the evolution of resistance. The principal factors determining the rate at which resistance evolves appear to be (i) the starting frequency of resistance, (ii) the level and pattern of drug use, (iii) the drug's pharmacokinetic properties, (iv) the number of genes required to encode resistance, (v) the level of sexual recombination in the parasite population, (vi) intrahost dynamics and, in particular, whether 'crowding' effects are present, (vii) the genetic basis of resistance and (viii) the number of individual parasites in an infection. The relative importance of these factors depends on the biology of the organisms under consideration and external factors such as the extent to which the infrastructure of health care delivery constrains the practicalities of drug regimens." @default.
- W2144029319 created "2016-06-24" @default.
- W2144029319 creator A5018487477 @default.
- W2144029319 date "2001-11-01" @default.
- W2144029319 modified "2023-10-17" @default.
- W2144029319 title "Modelling parasite drug resistance: lessons for management and control strategies" @default.
- W2144029319 cites W146952130 @default.
- W2144029319 cites W178380885 @default.
- W2144029319 cites W1935016814 @default.
- W2144029319 cites W1974870120 @default.
- W2144029319 cites W1980128709 @default.
- W2144029319 cites W1980288059 @default.
- W2144029319 cites W1990484067 @default.
- W2144029319 cites W2001700040 @default.
- W2144029319 cites W2009258477 @default.
- W2144029319 cites W2028410321 @default.
- W2144029319 cites W2029348311 @default.
- W2144029319 cites W2033818100 @default.
- W2144029319 cites W2047282512 @default.
- W2144029319 cites W2052227367 @default.
- W2144029319 cites W2058996307 @default.
- W2144029319 cites W2059838568 @default.
- W2144029319 cites W2063013012 @default.
- W2144029319 cites W2094331166 @default.
- W2144029319 cites W2103437642 @default.
- W2144029319 cites W2142999550 @default.
- W2144029319 cites W2158722434 @default.
- W2144029319 cites W2159680005 @default.
- W2144029319 cites W2160884305 @default.
- W2144029319 cites W2165730332 @default.
- W2144029319 cites W2169301888 @default.
- W2144029319 doi "https://doi.org/10.1046/j.1365-3156.2001.00800.x" @default.
- W2144029319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11703842" @default.
- W2144029319 hasPublicationYear "2001" @default.
- W2144029319 type Work @default.
- W2144029319 sameAs 2144029319 @default.
- W2144029319 citedByCount "48" @default.
- W2144029319 countsByYear W21440293192012 @default.
- W2144029319 countsByYear W21440293192013 @default.
- W2144029319 countsByYear W21440293192015 @default.
- W2144029319 countsByYear W21440293192016 @default.
- W2144029319 countsByYear W21440293192017 @default.
- W2144029319 countsByYear W21440293192018 @default.
- W2144029319 countsByYear W21440293192019 @default.
- W2144029319 countsByYear W21440293192020 @default.
- W2144029319 countsByYear W21440293192022 @default.
- W2144029319 crossrefType "journal-article" @default.
- W2144029319 hasAuthorship W2144029319A5018487477 @default.
- W2144029319 hasConcept C114851261 @default.
- W2144029319 hasConcept C150903083 @default.
- W2144029319 hasConcept C18903297 @default.
- W2144029319 hasConcept C2780035454 @default.
- W2144029319 hasConcept C2908647359 @default.
- W2144029319 hasConcept C54355233 @default.
- W2144029319 hasConcept C57473165 @default.
- W2144029319 hasConcept C71924100 @default.
- W2144029319 hasConcept C86803240 @default.
- W2144029319 hasConcept C98274493 @default.
- W2144029319 hasConcept C99454951 @default.
- W2144029319 hasConceptScore W2144029319C114851261 @default.
- W2144029319 hasConceptScore W2144029319C150903083 @default.
- W2144029319 hasConceptScore W2144029319C18903297 @default.
- W2144029319 hasConceptScore W2144029319C2780035454 @default.
- W2144029319 hasConceptScore W2144029319C2908647359 @default.
- W2144029319 hasConceptScore W2144029319C54355233 @default.
- W2144029319 hasConceptScore W2144029319C57473165 @default.
- W2144029319 hasConceptScore W2144029319C71924100 @default.
- W2144029319 hasConceptScore W2144029319C86803240 @default.
- W2144029319 hasConceptScore W2144029319C98274493 @default.
- W2144029319 hasConceptScore W2144029319C99454951 @default.
- W2144029319 hasIssue "11" @default.
- W2144029319 hasLocation W21440293191 @default.
- W2144029319 hasLocation W21440293192 @default.
- W2144029319 hasOpenAccess W2144029319 @default.
- W2144029319 hasPrimaryLocation W21440293191 @default.
- W2144029319 hasRelatedWork W2086452998 @default.
- W2144029319 hasRelatedWork W2294187591 @default.
- W2144029319 hasRelatedWork W2366105490 @default.
- W2144029319 hasRelatedWork W2492624138 @default.
- W2144029319 hasRelatedWork W2964191569 @default.
- W2144029319 hasRelatedWork W2996713688 @default.
- W2144029319 hasRelatedWork W3044360021 @default.
- W2144029319 hasRelatedWork W4206379684 @default.
- W2144029319 hasRelatedWork W4287027430 @default.
- W2144029319 hasRelatedWork W2580680567 @default.
- W2144029319 hasVolume "6" @default.
- W2144029319 isParatext "false" @default.
- W2144029319 isRetracted "false" @default.
- W2144029319 magId "2144029319" @default.
- W2144029319 workType "article" @default.