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• W2144050619 abstract "Conocer las características y supervivencia del carcinoma broncogénico (CB) diagnosticado en las unidades de neumología del Principado de Asturias.Se ha realizado un estudio observacional retrospectivo en el que se ha empleado un protocolo común de recogida de datos. Se incluyeron los CB diagnosticados en el año 2001 con confirmación citohistológica o por concordancia basada en datos clínicos, radiológicos y/o endoscópicos.Las tasas de incidencia estándar para toda la población, varones y mujeres, ajustadas a la población mundial fueron de 22,4, 42,6 y 4,6/100.000 habitantes, respectivamente. El 92% era varón; la edad media (± desviación estándar) fue de 67 ± 10,9 años. Tenía hábito tabáquico el 98% de los varones y el 44% de las mujeres. Se alcanzó confirmación citohistológica en el 92% y la mayoría era CB no microcíticos (81,4%). En el momento del diagnóstico el 65% de los pacientes tenía enfermedad avanzada, con metastasis a distancia en el 26,6% de los CB no microcíticos y en el 52,8% de los de células pequeñas. Se trató con cirugía el 21,3% de los casos, con quimioterapia sola o asociada a radioterapia el 43,1%, con radioterapia exclusivamente el 9,3% y recibió tratamiento paliativo el 26,2%. La mediana de supervivencia global, en semanas, fue de 36,4 (intervalo de confianza [IC] del 95%, 29,4-43,4) y para los istintos tratamientos fue la siguiente: para la cirugía, 69,3 (IC del 95%, 49-9,5); para la quimioterapia sola o asociada a radioterapia, 39,6 (IC del 95%, 31,2-48); para la radioterapia sola, 30 (IC del 95%, 15,4-44,6), y para el paliativo, 13,3 (IC del 95%, 5,9-20,6) (p < 0,05).En nuestra región, las características del CB en cuanto a edad, sexo, incidencia, histología, extension tumoral y tabaquismo no difieren significativamente de las halladas en otras áreas del ámbito nacional. El tabaquismo activo es la causa fundamental de su alta prevalencia. Se ofreció solamente tratamiento de soporte al 26%. El porcentaje de pacientes quirúrgicos es bajo.To gather information on the disease characteristics and survival rate of patients diagnosed with bronchogenic carcinoma in the respiratory medicine departments of hospitals in Asturias, Spain.This was a retrospective observational study carried out using a standardized data collection protocol. All cases of lung cancer diagnosed during 2001 were included provided there was cytologic or histologic confirmation or they fulfilled a series of clinical, radiological, and/or endoscopic criteria consistent with such a diagnosis.Standard incidence rates adjusted to the world population were 22.4, 42.6, and 4.6 per 100 000 population for the whole population, men, and women respectively. The mean (SD) age was 67 (10.9) years, and 92% of the patients were men. Overall, 98% of the men and 44% of the women were smokers. Diagnosis was confirmed by cytologic or histologic findings in 92% of patients, and the majority were non-small cell tumors (81.4%). At the time of diagnosis, 65% of the patients had advanced disease, with distant metastasis in 26.6% of the non-small cell cancers and 52.8% of the small cell cancers. Patients received surgical treatment in 21.3% of cases, chemotherapy alone or combined with radiation therapy in 43.1%, and radiation therapy alone in 9.3%. In 26.2% of patients only palliative care was given. Overall, median urvival in weeks was 36.4 (95% confidence interval [CI], 29.4-43.4). Median survival by treatment type was as follows: 69.3 (95% CI, 49-9.5) for surgery; 39.6 (95% CI, 31.2-48) for chemotherapy alone or with radiation therapy; 30 (95% CI, 15.4-44.6) for radiation therapy alone; and 13.3 (95% CI, 5.9-20.6) for patients who received palliative care alone (P<.05).The findings with respect to age, sex, incidence, histology, extent of tumor, and smoking status of patients with bronchogenic carcinoma in our region does not differ significantly from those reported for other areas of Spain. Current smoking is the primary cause of the high prevalence of this disease. Twenty-six percent of patients received only palliative care. The percentage of patients treated with surgery was low." @default.
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• W2144050619 date "2001-01-01" @default.
• W2144050619 modified "2023-09-28" @default.
• W2144050619 title "Tendencias actuales en el tratamiento del carcinoma broncopulmonar no microcítico localmente avanzado. Tratamientos combinados de quimioterapia y radioterapia" @default.
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• W2144050619 doi "https://doi.org/10.1016/s0300-2896(01)75114-9" @default.
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