Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144114720> ?p ?o ?g. }
- W2144114720 endingPage "313" @default.
- W2144114720 startingPage "303" @default.
- W2144114720 abstract "Bleomycin sulphate-loaded porous microspheres were prepared using modified solvent evaporation method (w/o/w) using PLGA50:50 as a polymeric system. The prepared microspheres were incorporated in pluronic® (F127) based thermoreversible gel to develop a depot formulation. Various process parameters as solvent evaporation temperature and formulation parameters such as surfactant concentration, volume of internal and external phase and drug-to-polymer ratio were optimized for enhancing percentage drug entrapment, percentage drug loading and desired release profile by controlling size and porosity of the microspheres. Microspheres were characterized for particle size, zeta potential, surface morphology, percentage drug loading and in vitro drug release study after incorporated in gel. The formulated microspheres were porous in nature and showed biphasic in vitro drug release profile. The microspheres incorporated in pluronic® (F127) gel showed sustained release up to 1 week and may be useful for treatment of squamous cell carcinoma with better therapeutic effect." @default.
- W2144114720 created "2016-06-24" @default.
- W2144114720 creator A5016231901 @default.
- W2144114720 creator A5021773285 @default.
- W2144114720 creator A5060173174 @default.
- W2144114720 creator A5084390401 @default.
- W2144114720 date "2010-01-01" @default.
- W2144114720 modified "2023-10-18" @default.
- W2144114720 title "Preparation of porous PLGA microspheres with thermoreversible gel to modulate drug release profile of water-soluble drug: Bleomycin sulphate" @default.
- W2144114720 cites W118642107 @default.
- W2144114720 cites W1964493417 @default.
- W2144114720 cites W1964669428 @default.
- W2144114720 cites W1972544495 @default.
- W2144114720 cites W1980352894 @default.
- W2144114720 cites W1981581818 @default.
- W2144114720 cites W1983067875 @default.
- W2144114720 cites W1998731236 @default.
- W2144114720 cites W1998875753 @default.
- W2144114720 cites W1999019450 @default.
- W2144114720 cites W2000933576 @default.
- W2144114720 cites W2001558630 @default.
- W2144114720 cites W2002816233 @default.
- W2144114720 cites W2007669532 @default.
- W2144114720 cites W2009057674 @default.
- W2144114720 cites W2011594076 @default.
- W2144114720 cites W2014929746 @default.
- W2144114720 cites W2015461951 @default.
- W2144114720 cites W2018306057 @default.
- W2144114720 cites W2022123157 @default.
- W2144114720 cites W2024088680 @default.
- W2144114720 cites W2032157866 @default.
- W2144114720 cites W2040716933 @default.
- W2144114720 cites W2041698490 @default.
- W2144114720 cites W2044716063 @default.
- W2144114720 cites W2046654997 @default.
- W2144114720 cites W2049756302 @default.
- W2144114720 cites W2052609043 @default.
- W2144114720 cites W2054108381 @default.
- W2144114720 cites W2057273206 @default.
- W2144114720 cites W2063159268 @default.
- W2144114720 cites W2066941149 @default.
- W2144114720 cites W2070303120 @default.
- W2144114720 cites W2072814312 @default.
- W2144114720 cites W2078189651 @default.
- W2144114720 cites W2078639851 @default.
- W2144114720 cites W2081001487 @default.
- W2144114720 cites W2084462474 @default.
- W2144114720 cites W2089461282 @default.
- W2144114720 cites W2093017893 @default.
- W2144114720 cites W2098018230 @default.
- W2144114720 cites W2098272429 @default.
- W2144114720 cites W2102826200 @default.
- W2144114720 cites W2104417536 @default.
- W2144114720 cites W2111870349 @default.
- W2144114720 cites W2125100502 @default.
- W2144114720 cites W2136875114 @default.
- W2144114720 cites W2156368993 @default.
- W2144114720 cites W30025017 @default.
- W2144114720 doi "https://doi.org/10.3109/02652040903191818" @default.
- W2144114720 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20128747" @default.
- W2144114720 hasPublicationYear "2010" @default.
- W2144114720 type Work @default.
- W2144114720 sameAs 2144114720 @default.
- W2144114720 citedByCount "10" @default.
- W2144114720 countsByYear W21441147202012 @default.
- W2144114720 countsByYear W21441147202013 @default.
- W2144114720 countsByYear W21441147202014 @default.
- W2144114720 countsByYear W21441147202016 @default.
- W2144114720 countsByYear W21441147202017 @default.
- W2144114720 crossrefType "journal-article" @default.
- W2144114720 hasAuthorship W2144114720A5016231901 @default.
- W2144114720 hasAuthorship W2144114720A5021773285 @default.
- W2144114720 hasAuthorship W2144114720A5060173174 @default.
- W2144114720 hasAuthorship W2144114720A5084390401 @default.
- W2144114720 hasConcept C101335993 @default.
- W2144114720 hasConcept C127413603 @default.
- W2144114720 hasConcept C13245373 @default.
- W2144114720 hasConcept C155672457 @default.
- W2144114720 hasConcept C15920480 @default.
- W2144114720 hasConcept C159985019 @default.
- W2144114720 hasConcept C171250308 @default.
- W2144114720 hasConcept C178790620 @default.
- W2144114720 hasConcept C185592680 @default.
- W2144114720 hasConcept C187530423 @default.
- W2144114720 hasConcept C192562407 @default.
- W2144114720 hasConcept C2777521759 @default.
- W2144114720 hasConcept C2779820397 @default.
- W2144114720 hasConcept C2780165375 @default.
- W2144114720 hasConcept C2780471494 @default.
- W2144114720 hasConcept C42360764 @default.
- W2144114720 hasConcept C43617362 @default.
- W2144114720 hasConcept C521977710 @default.
- W2144114720 hasConcept C58226133 @default.
- W2144114720 hasConcept C6648577 @default.
- W2144114720 hasConcept C86181022 @default.
- W2144114720 hasConceptScore W2144114720C101335993 @default.
- W2144114720 hasConceptScore W2144114720C127413603 @default.
- W2144114720 hasConceptScore W2144114720C13245373 @default.