FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144195280> ?p ?o ?g. }

• W2144195280 endingPage "195" @default.
• W2144195280 startingPage "187" @default.
• W2144195280 abstract "The conjugative plasmid pOLA52, which confers resistance to olaquindox and other antimicrobial agents through a multidrug efflux pump, was investigated for its ability to promote biofilm formation in Escherichia coli. Screening of a transposon-mutagenized pOLA52 clone library revealed several biofilm-deficient mutants, which all mapped within a putative operon with high homology to the mrkABCDF operon of Klebsiella pneumoniae, where these genes are responsible for type 3 fimbriae expression, attachment to surfaces and biofilm formation. Biofilm formation in microtitre plates and in urinary catheters of clones containing pOLA52 with a disrupted putative mrk operon was reduced by more than 100-fold and 2-fold, respectively, compared to mutants with an intact mrk operon. The conjugative transfer rate of pOLA52 was also significantly lower when the mrk operon was disrupted. Through reverse transcriptase analysis, it was demonstrated that the genes contained in the putative mrk operon were linked and likely to be expressed as a single operon. Immunoblotting with type 3 fimbriae (MrkA)-specific antibodies further verified expression of type 3 fimbriae. When transferred to other, potentially pathogenic, members of the family Enterobacteriaceae, including Klebsiella pneumoniae, Salmonella Typhimurium, Kluyvera sp. and Enterobacter aerogenes, pOLA52 facilitated increased biofilm formation. pOLA52 is believed to represent the first example of a conjugative plasmid encoding type 3 fimbriae, resulting in enhanced conjugation frequencies and biofilm formation of the plasmid-harbouring strain." @default.
• W2144195280 created "2016-06-24" @default.
• W2144195280 creator A5004457901 @default.
• W2144195280 creator A5024593114 @default.
• W2144195280 creator A5028072132 @default.
• W2144195280 creator A5075847298 @default.
• W2144195280 creator A5090059968 @default.
• W2144195280 date "2008-01-01" @default.
• W2144195280 modified "2023-10-14" @default.
• W2144195280 title "Type 3 fimbriae, encoded by the conjugative plasmid pOLA52, enhance biofilm formation and transfer frequencies in Enterobacteriaceae strains" @default.
• W2144195280 cites W1842286347 @default.
• W2144195280 cites W1861122134 @default.
• W2144195280 cites W1973980900 @default.
• W2144195280 cites W1980702664 @default.
• W2144195280 cites W2000463431 @default.
• W2144195280 cites W2003862523 @default.
• W2144195280 cites W2067477145 @default.
• W2144195280 cites W2073073309 @default.
• W2144195280 cites W2078327104 @default.
• W2144195280 cites W2087140501 @default.
• W2144195280 cites W2090222801 @default.
• W2144195280 cites W2100283500 @default.
• W2144195280 cites W2105679233 @default.
• W2144195280 cites W2109434556 @default.
• W2144195280 cites W2109842871 @default.
• W2144195280 cites W2110297715 @default.
• W2144195280 cites W2119633818 @default.
• W2144195280 cites W2122721391 @default.
• W2144195280 cites W2126183567 @default.
• W2144195280 cites W2131727615 @default.
• W2144195280 cites W2132295042 @default.
• W2144195280 cites W2133221340 @default.
• W2144195280 cites W2136382027 @default.
• W2144195280 cites W2136453037 @default.
• W2144195280 cites W2136871577 @default.
• W2144195280 cites W2140396153 @default.
• W2144195280 cites W2142518288 @default.
• W2144195280 cites W2142710255 @default.
• W2144195280 cites W2146756785 @default.
• W2144195280 cites W2150691826 @default.
• W2144195280 cites W2151932607 @default.
• W2144195280 cites W2156886382 @default.
• W2144195280 cites W2168088718 @default.
• W2144195280 cites W4230690150 @default.
• W2144195280 doi "https://doi.org/10.1099/mic.0.2007/010454-0" @default.
• W2144195280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18174137" @default.
• W2144195280 hasPublicationYear "2008" @default.
• W2144195280 type Work @default.
• W2144195280 sameAs 2144195280 @default.
• W2144195280 citedByCount "103" @default.
• W2144195280 countsByYear W21441952802012 @default.
• W2144195280 countsByYear W21441952802013 @default.
• W2144195280 countsByYear W21441952802014 @default.
• W2144195280 countsByYear W21441952802015 @default.
• W2144195280 countsByYear W21441952802016 @default.
• W2144195280 countsByYear W21441952802017 @default.
• W2144195280 countsByYear W21441952802018 @default.
• W2144195280 countsByYear W21441952802019 @default.
• W2144195280 countsByYear W21441952802020 @default.
• W2144195280 countsByYear W21441952802021 @default.
• W2144195280 countsByYear W21441952802022 @default.
• W2144195280 countsByYear W21441952802023 @default.
• W2144195280 crossrefType "journal-article" @default.
• W2144195280 hasAuthorship W2144195280A5004457901 @default.
• W2144195280 hasAuthorship W2144195280A5024593114 @default.
• W2144195280 hasAuthorship W2144195280A5028072132 @default.
• W2144195280 hasAuthorship W2144195280A5075847298 @default.
• W2144195280 hasAuthorship W2144195280A5090059968 @default.
• W2144195280 hasBestOaLocation W21441952801 @default.
• W2144195280 hasConcept C104317684 @default.
• W2144195280 hasConcept C143065580 @default.
• W2144195280 hasConcept C203075996 @default.
• W2144195280 hasConcept C22744801 @default.
• W2144195280 hasConcept C2776265613 @default.
• W2144195280 hasConcept C2777058267 @default.
• W2144195280 hasConcept C2778910516 @default.
• W2144195280 hasConcept C39103817 @default.
• W2144195280 hasConcept C523546767 @default.
• W2144195280 hasConcept C54355233 @default.
• W2144195280 hasConcept C547475151 @default.
• W2144195280 hasConcept C58123911 @default.
• W2144195280 hasConcept C86803240 @default.
• W2144195280 hasConcept C89423630 @default.
• W2144195280 hasConceptScore W2144195280C104317684 @default.
• W2144195280 hasConceptScore W2144195280C143065580 @default.
• W2144195280 hasConceptScore W2144195280C203075996 @default.
• W2144195280 hasConceptScore W2144195280C22744801 @default.
• W2144195280 hasConceptScore W2144195280C2776265613 @default.
• W2144195280 hasConceptScore W2144195280C2777058267 @default.
• W2144195280 hasConceptScore W2144195280C2778910516 @default.
• W2144195280 hasConceptScore W2144195280C39103817 @default.
• W2144195280 hasConceptScore W2144195280C523546767 @default.
• W2144195280 hasConceptScore W2144195280C54355233 @default.
• W2144195280 hasConceptScore W2144195280C547475151 @default.
• W2144195280 hasConceptScore W2144195280C58123911 @default.
• W2144195280 hasConceptScore W2144195280C86803240 @default.
• W2144195280 hasConceptScore W2144195280C89423630 @default.
• W2144195280 hasIssue "1" @default.

• next