FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144368456> ?p ?o ?g. }

• W2144368456 endingPage "1452" @default.
• W2144368456 startingPage "1445" @default.
• W2144368456 abstract "Abstract Background Sacral nerve stimulation is an established treatment for faecal incontinence. Nearly half of all patients experience loss of efficacy at some point. Standard reprogramming restores efficacy for some, but not all, patients. This study aimed to determine whether alternative stimulator settings would increase treatment efficacy. Methods Patients with sustained loss of efficacy were recruited from two international specialist centres. A number of alternative stimulation parameters were tested using a double-blind randomized crossover study design. Stimulation settings tested were pulse frequencies of 6·9 and 31 Hz, and pulse widths of 90 and 330 µs, compared with one standard setting of 14 Hz/210 µs. Treatment efficacy was evaluated using a disease-specific quality-of-life score (Fecal Incontinence Quality of Life Scale, FIQLS) and a bowel habit diary completed before randomization, during the study period and after 3 months of follow-up with one preferred setting. Results Fifteen patients were analysed. With one preferred setting, three of four subdomains in the FIQLS improved significantly. The mean(s.d.) total number of incontinence episodes dropped from 11·7(10·8) to 4·8(4·5) per 3 weeks (P = 0·011) and improvements were maintained after 3 months of follow-up. Optimal pacemaker settings were individual, but a trend towards highest patient satisfaction and improved treatment outcome was evident for high-frequency stimulation (31 Hz/210 µs), which was preferred by eight of the 15 patients. Conclusion Patients experiencing loss of efficacy can experience improvement if alternative pacemaker settings are tested. High-frequency stimulation (31 Hz/210 µs) was preferred by more than half of the patients, and improved treatment outcome was sustained at 3 months. Registration number: NCT01254695 (http://www.clinicaltrials.gov)." @default.
• W2144368456 created "2016-06-24" @default.
• W2144368456 creator A5018492729 @default.
• W2144368456 creator A5028601350 @default.
• W2144368456 creator A5034877444 @default.
• W2144368456 creator A5041097161 @default.
• W2144368456 creator A5071739165 @default.
• W2144368456 creator A5081693607 @default.
• W2144368456 creator A5087805470 @default.
• W2144368456 date "2012-09-07" @default.
• W2144368456 modified "2023-09-25" @default.
• W2144368456 title "Randomized double-blind crossover study of alternative stimulator settings in sacral nerve stimulation for faecal incontinence" @default.
• W2144368456 cites W1273379855 @default.
• W2144368456 cites W1494878174 @default.
• W2144368456 cites W1510824734 @default.
• W2144368456 cites W1964910309 @default.
• W2144368456 cites W1968269596 @default.
• W2144368456 cites W1983392967 @default.
• W2144368456 cites W1992103194 @default.
• W2144368456 cites W1993049484 @default.
• W2144368456 cites W1993972569 @default.
• W2144368456 cites W2007826917 @default.
• W2144368456 cites W2008066850 @default.
• W2144368456 cites W2010222736 @default.
• W2144368456 cites W2010666992 @default.
• W2144368456 cites W2015457931 @default.
• W2144368456 cites W2021379632 @default.
• W2144368456 cites W2022614231 @default.
• W2144368456 cites W2027622170 @default.
• W2144368456 cites W2028654164 @default.
• W2144368456 cites W2032552897 @default.
• W2144368456 cites W2033673596 @default.
• W2144368456 cites W2035890610 @default.
• W2144368456 cites W2042834504 @default.
• W2144368456 cites W2055018648 @default.
• W2144368456 cites W2061096503 @default.
• W2144368456 cites W2068788951 @default.
• W2144368456 cites W2083961035 @default.
• W2144368456 cites W2085307345 @default.
• W2144368456 cites W2088498970 @default.
• W2144368456 cites W2108882655 @default.
• W2144368456 cites W2115743933 @default.
• W2144368456 cites W2117300470 @default.
• W2144368456 cites W2122496698 @default.
• W2144368456 cites W2312934273 @default.
• W2144368456 cites W2418560777 @default.
• W2144368456 doi "https://doi.org/10.1002/bjs.8867" @default.
• W2144368456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22961528" @default.
• W2144368456 hasPublicationYear "2012" @default.
• W2144368456 type Work @default.
• W2144368456 sameAs 2144368456 @default.
• W2144368456 citedByCount "30" @default.
• W2144368456 countsByYear W21443684562013 @default.
• W2144368456 countsByYear W21443684562014 @default.
• W2144368456 countsByYear W21443684562015 @default.
• W2144368456 countsByYear W21443684562016 @default.
• W2144368456 countsByYear W21443684562017 @default.
• W2144368456 countsByYear W21443684562018 @default.
• W2144368456 countsByYear W21443684562019 @default.
• W2144368456 countsByYear W21443684562020 @default.
• W2144368456 countsByYear W21443684562021 @default.
• W2144368456 countsByYear W21443684562022 @default.
• W2144368456 countsByYear W21443684562023 @default.
• W2144368456 crossrefType "journal-article" @default.
• W2144368456 hasAuthorship W2144368456A5018492729 @default.
• W2144368456 hasAuthorship W2144368456A5028601350 @default.
• W2144368456 hasAuthorship W2144368456A5034877444 @default.
• W2144368456 hasAuthorship W2144368456A5041097161 @default.
• W2144368456 hasAuthorship W2144368456A5071739165 @default.
• W2144368456 hasAuthorship W2144368456A5081693607 @default.
• W2144368456 hasAuthorship W2144368456A5087805470 @default.
• W2144368456 hasBestOaLocation W21443684561 @default.
• W2144368456 hasConcept C126322002 @default.
• W2144368456 hasConcept C141071460 @default.
• W2144368456 hasConcept C142724271 @default.
• W2144368456 hasConcept C159110408 @default.
• W2144368456 hasConcept C168563851 @default.
• W2144368456 hasConcept C204243189 @default.
• W2144368456 hasConcept C204787440 @default.
• W2144368456 hasConcept C24998067 @default.
• W2144368456 hasConcept C27081682 @default.
• W2144368456 hasConcept C2775944032 @default.
• W2144368456 hasConcept C2776813522 @default.
• W2144368456 hasConcept C2779951463 @default.
• W2144368456 hasConcept C71924100 @default.
• W2144368456 hasConcept C87813604 @default.
• W2144368456 hasConceptScore W2144368456C126322002 @default.
• W2144368456 hasConceptScore W2144368456C141071460 @default.
• W2144368456 hasConceptScore W2144368456C142724271 @default.
• W2144368456 hasConceptScore W2144368456C159110408 @default.
• W2144368456 hasConceptScore W2144368456C168563851 @default.
• W2144368456 hasConceptScore W2144368456C204243189 @default.
• W2144368456 hasConceptScore W2144368456C204787440 @default.
• W2144368456 hasConceptScore W2144368456C24998067 @default.
• W2144368456 hasConceptScore W2144368456C27081682 @default.
• W2144368456 hasConceptScore W2144368456C2775944032 @default.
• W2144368456 hasConceptScore W2144368456C2776813522 @default.
• W2144368456 hasConceptScore W2144368456C2779951463 @default.

• next