Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144374538> ?p ?o ?g. }
- W2144374538 endingPage "4345" @default.
- W2144374538 startingPage "4334" @default.
- W2144374538 abstract "Developmental adjustments in the balance of excitation and inhibition are thought to constrain the plasticity of sensory areas of the cortex. It is unknown however, how changes in excitatory or inhibitory neurochemical expression (glutamate, g-aminobutyric acid (GABA)) contribute to skill acquisition during development. Here we used single-voxel proton magnetic resonance spectroscopy (1 H-MRS) to reveal how differences in cortical glutamate vs. GABA ratios relate to face proficiency and working memory abilities in children and adults. We show that higher glutamate levels in the inferior frontal gyrus correlated positively with face processing proficiency in the children, but not the adults, an effect which was independent of age-dependent differences in underlying cortical gray matter. Moreover, we found that glutamate/GABA levels and gray matter volume are dissociated at the different maturational stages. These findings suggest that increased excitation during development is linked to neuroplasticity and the acquisition of new cognitive skills. They also offer a new, neurochemical approach to investigating the relationship between cognitive performance and brain development across the lifespan." @default.
- W2144374538 created "2016-06-24" @default.
- W2144374538 creator A5002385827 @default.
- W2144374538 creator A5016505042 @default.
- W2144374538 creator A5016831328 @default.
- W2144374538 creator A5018565112 @default.
- W2144374538 creator A5078356087 @default.
- W2144374538 date "2015-09-09" @default.
- W2144374538 modified "2023-10-10" @default.
- W2144374538 title "Linking <scp>GABA</scp> and glutamate levels to cognitive skill acquisition during development" @default.
- W2144374538 cites W1547906203 @default.
- W2144374538 cites W1967281219 @default.
- W2144374538 cites W1967721763 @default.
- W2144374538 cites W1969772297 @default.
- W2144374538 cites W1970397428 @default.
- W2144374538 cites W1972172513 @default.
- W2144374538 cites W1976743253 @default.
- W2144374538 cites W1979471034 @default.
- W2144374538 cites W1988751127 @default.
- W2144374538 cites W1990234940 @default.
- W2144374538 cites W1993796046 @default.
- W2144374538 cites W2000469915 @default.
- W2144374538 cites W2001319329 @default.
- W2144374538 cites W2001716460 @default.
- W2144374538 cites W2002278473 @default.
- W2144374538 cites W2003313303 @default.
- W2144374538 cites W2004995289 @default.
- W2144374538 cites W2010114701 @default.
- W2144374538 cites W2012139659 @default.
- W2144374538 cites W2013022413 @default.
- W2144374538 cites W2018692532 @default.
- W2144374538 cites W2019826571 @default.
- W2144374538 cites W2020049356 @default.
- W2144374538 cites W2020781956 @default.
- W2144374538 cites W2023613906 @default.
- W2144374538 cites W2024274726 @default.
- W2144374538 cites W2026353330 @default.
- W2144374538 cites W2030454297 @default.
- W2144374538 cites W2030825382 @default.
- W2144374538 cites W2037316381 @default.
- W2144374538 cites W2038979894 @default.
- W2144374538 cites W2039065383 @default.
- W2144374538 cites W2044175039 @default.
- W2144374538 cites W2045307802 @default.
- W2144374538 cites W2052307247 @default.
- W2144374538 cites W2061198654 @default.
- W2144374538 cites W2072652550 @default.
- W2144374538 cites W2074112754 @default.
- W2144374538 cites W2079166249 @default.
- W2144374538 cites W2087965730 @default.
- W2144374538 cites W2089936360 @default.
- W2144374538 cites W2092112280 @default.
- W2144374538 cites W2095567388 @default.
- W2144374538 cites W2096179601 @default.
- W2144374538 cites W2096979833 @default.
- W2144374538 cites W2098406191 @default.
- W2144374538 cites W2100239625 @default.
- W2144374538 cites W2100617174 @default.
- W2144374538 cites W2101520758 @default.
- W2144374538 cites W2101790396 @default.
- W2144374538 cites W2108722540 @default.
- W2144374538 cites W2110711096 @default.
- W2144374538 cites W2114056587 @default.
- W2144374538 cites W2115679772 @default.
- W2144374538 cites W2117329255 @default.
- W2144374538 cites W2119021247 @default.
- W2144374538 cites W2119848633 @default.
- W2144374538 cites W2119997223 @default.
- W2144374538 cites W2120731293 @default.
- W2144374538 cites W2122739133 @default.
- W2144374538 cites W2127421809 @default.
- W2144374538 cites W2132934054 @default.
- W2144374538 cites W2134462887 @default.
- W2144374538 cites W2139606992 @default.
- W2144374538 cites W2141313070 @default.
- W2144374538 cites W2148792824 @default.
- W2144374538 cites W2157080326 @default.
- W2144374538 cites W2158463114 @default.
- W2144374538 cites W2158974830 @default.
- W2144374538 cites W2167551960 @default.
- W2144374538 cites W2168282726 @default.
- W2144374538 cites W2416819300 @default.
- W2144374538 cites W4211063728 @default.
- W2144374538 doi "https://doi.org/10.1002/hbm.22921" @default.
- W2144374538 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4832309" @default.
- W2144374538 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26350618" @default.
- W2144374538 hasPublicationYear "2015" @default.
- W2144374538 type Work @default.
- W2144374538 sameAs 2144374538 @default.
- W2144374538 citedByCount "48" @default.
- W2144374538 countsByYear W21443745382015 @default.
- W2144374538 countsByYear W21443745382016 @default.
- W2144374538 countsByYear W21443745382017 @default.
- W2144374538 countsByYear W21443745382018 @default.
- W2144374538 countsByYear W21443745382019 @default.
- W2144374538 countsByYear W21443745382020 @default.
- W2144374538 countsByYear W21443745382021 @default.
- W2144374538 countsByYear W21443745382022 @default.