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• W2144474305 abstract "Many diseases and injuries lead to loss of motor function. Can we reanimate paralyzed limbs to produce effective, graceful movements? Recent insights into the function of the motor system and greatly improved computing capabilities have made this a realistic goal, even in the absence of regeneration of motor pathways. Some approaches involve stimulating muscles, nerves or the spinal cord below the level of a lesion. Others involve recording a subject's intention from the cortex, and using this intention to control computers, robots or systems for stimulating the limbs. Here, we critically analyze the possibilities and limitations of various approaches for restoring motor function based on recent human trials and underlying neuroscience research. Many diseases and injuries lead to loss of motor function. Can we reanimate paralyzed limbs to produce effective, graceful movements? Recent insights into the function of the motor system and greatly improved computing capabilities have made this a realistic goal, even in the absence of regeneration of motor pathways. Some approaches involve stimulating muscles, nerves or the spinal cord below the level of a lesion. Others involve recording a subject's intention from the cortex, and using this intention to control computers, robots or systems for stimulating the limbs. Here, we critically analyze the possibilities and limitations of various approaches for restoring motor function based on recent human trials and underlying neuroscience research." @default.
• W2144474305 created "2016-06-24" @default.
• W2144474305 creator A5028712125 @default.
• W2144474305 creator A5068967397 @default.
• W2144474305 date "2005-10-01" @default.
• W2144474305 modified "2023-10-15" @default.
• W2144474305 title "Reanimating limbs after injury or disease" @default.
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• W2144474305 doi "https://doi.org/10.1016/j.tins.2005.07.007" @default.
• W2144474305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16083974" @default.
• W2144474305 hasPublicationYear "2005" @default.
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