FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144543154> ?p ?o ?g. }

• W2144543154 endingPage "3810" @default.
• W2144543154 startingPage "3805" @default.
• W2144543154 abstract "Background. Coding variants in the apolipoprotein L1 gene (APOL1) are strongly associated with non-diabetic nephropathy in African Americans. ApoL1 proteins associate with high-density lipoprotein (HDL) particles in the circulation. Plasma HDL particle subclass concentrations were compared in 73 African Americans based on APOL1 genotypes to detect differences potentially contributing to renal disease. Methods. HDL subclass concentrations were measured using nuclear magnetic resonance spectroscopy in African American first-degree relatives of patients with non-diabetic end-stage renal disease. Participants had estimated glomerular filtration rates (GFRs) > 80 mL/min and lacked albuminuria. Additive effects of the number of APOL1 risk variants on natural logarithm-transformed HDL subclass concentrations were computed. Results. Participants were 58.9% female with mean ± SD age 47.2 ± 13.3 years and GFR 92.4 ± 18.8 mL/min. The numbers with 2, 1 and 0 APOL1 nephropathy risk variants, respectively, were 36, 17 and 20. Mean ± SD medium-sized HDL concentrations were significantly lower for each additional APOL1 risk variant (2 versus 1 versus 0 risk variants: 9.0 ± 5.6 versus 10.1 ± 5.5 versus 13.1 ± 8.2 μmol/L, respectively; P = 0.0222 unadjusted; P = 0.0162 triglyceride- and ancestry adjusted). Conclusions. Lower medium-sized HDL subclass concentrations are present in African Americans based on increasing numbers of APOL1 nephropathy risk variants. Potential mechanistic roles of altered medium HDL concentrations on APOL1-associated renal microvascular diseases should be evaluated." @default.
• W2144543154 created "2016-06-24" @default.
• W2144543154 creator A5000371933 @default.
• W2144543154 creator A5018798896 @default.
• W2144543154 creator A5019962931 @default.
• W2144543154 creator A5030650722 @default.
• W2144543154 creator A5032157653 @default.
• W2144543154 creator A5059128990 @default.
• W2144543154 creator A5059764563 @default.
• W2144543154 creator A5067252939 @default.
• W2144543154 creator A5069795479 @default.
• W2144543154 creator A5071033886 @default.
• W2144543154 creator A5073592065 @default.
• W2144543154 creator A5087036525 @default.
• W2144543154 date "2011-09-19" @default.
• W2144543154 modified "2023-09-23" @default.
• W2144543154 title "Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans" @default.
• W2144543154 cites W1535761714 @default.
• W2144543154 cites W1983891915 @default.
• W2144543154 cites W1984875752 @default.
• W2144543154 cites W1993418944 @default.
• W2144543154 cites W2005408272 @default.
• W2144543154 cites W2006985588 @default.
• W2144543154 cites W2010901347 @default.
• W2144543154 cites W2012109620 @default.
• W2144543154 cites W2022957257 @default.
• W2144543154 cites W2028684154 @default.
• W2144543154 cites W2030266800 @default.
• W2144543154 cites W2030803259 @default.
• W2144543154 cites W2037048041 @default.
• W2144543154 cites W2046201364 @default.
• W2144543154 cites W2055864845 @default.
• W2144543154 cites W2058286579 @default.
• W2144543154 cites W2070382695 @default.
• W2144543154 cites W2075251487 @default.
• W2144543154 cites W2078679613 @default.
• W2144543154 cites W2100586653 @default.
• W2144543154 cites W2110597957 @default.
• W2144543154 cites W2120202875 @default.
• W2144543154 cites W2121965895 @default.
• W2144543154 cites W2123196786 @default.
• W2144543154 cites W2124641083 @default.
• W2144543154 cites W2141731387 @default.
• W2144543154 cites W2146262274 @default.
• W2144543154 cites W2146509235 @default.
• W2144543154 cites W2149588710 @default.
• W2144543154 cites W2160180886 @default.
• W2144543154 cites W2162250105 @default.
• W2144543154 cites W2165590009 @default.
• W2144543154 cites W2166585544 @default.
• W2144543154 cites W2167032249 @default.
• W2144543154 cites W4247418557 @default.
• W2144543154 doi "https://doi.org/10.1093/ndt/gfr542" @default.
• W2144543154 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3203631" @default.
• W2144543154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21931123" @default.
• W2144543154 hasPublicationYear "2011" @default.
• W2144543154 type Work @default.
• W2144543154 sameAs 2144543154 @default.
• W2144543154 citedByCount "33" @default.
• W2144543154 countsByYear W21445431542012 @default.
• W2144543154 countsByYear W21445431542013 @default.
• W2144543154 countsByYear W21445431542014 @default.
• W2144543154 countsByYear W21445431542015 @default.
• W2144543154 countsByYear W21445431542016 @default.
• W2144543154 countsByYear W21445431542017 @default.
• W2144543154 countsByYear W21445431542019 @default.
• W2144543154 countsByYear W21445431542020 @default.
• W2144543154 countsByYear W21445431542021 @default.
• W2144543154 countsByYear W21445431542022 @default.
• W2144543154 crossrefType "journal-article" @default.
• W2144543154 hasAuthorship W2144543154A5000371933 @default.
• W2144543154 hasAuthorship W2144543154A5018798896 @default.
• W2144543154 hasAuthorship W2144543154A5019962931 @default.
• W2144543154 hasAuthorship W2144543154A5030650722 @default.
• W2144543154 hasAuthorship W2144543154A5032157653 @default.
• W2144543154 hasAuthorship W2144543154A5059128990 @default.
• W2144543154 hasAuthorship W2144543154A5059764563 @default.
• W2144543154 hasAuthorship W2144543154A5067252939 @default.
• W2144543154 hasAuthorship W2144543154A5069795479 @default.
• W2144543154 hasAuthorship W2144543154A5071033886 @default.
• W2144543154 hasAuthorship W2144543154A5073592065 @default.
• W2144543154 hasAuthorship W2144543154A5087036525 @default.
• W2144543154 hasBestOaLocation W21445431542 @default.
• W2144543154 hasConcept C126322002 @default.
• W2144543154 hasConcept C134018914 @default.
• W2144543154 hasConcept C159641895 @default.
• W2144543154 hasConcept C159654299 @default.
• W2144543154 hasConcept C203014093 @default.
• W2144543154 hasConcept C2776174234 @default.
• W2144543154 hasConcept C2776194381 @default.
• W2144543154 hasConcept C2778163477 @default.
• W2144543154 hasConcept C2780072125 @default.
• W2144543154 hasConcept C2780541478 @default.
• W2144543154 hasConcept C2781184683 @default.
• W2144543154 hasConcept C555293320 @default.
• W2144543154 hasConcept C62746215 @default.
• W2144543154 hasConcept C71924100 @default.
• W2144543154 hasConceptScore W2144543154C126322002 @default.

• next