FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144585073> ?p ?o ?g. }

• W2144585073 endingPage "220" @default.
• W2144585073 startingPage "213" @default.
• W2144585073 abstract "Abstract Beagle puppies infected with both canine parainfluenza virus type 2 (CPI2) and Bordetella bronchiseptica (Bb) develop more severe acute bronchiolitis and airways hyperresponsiveness than do those infected with CPI2 or Bb alone. The aim of our study was to characterize the inflammatory response associated with airway hyperresponsiveness, and to determine whether the inflammatory cell response of bronchoalveolar lavage fluid (BALF) reflected changes in the bronchioles in this model. We investigated 25 beagle puppies (ages 76 ± 5 days, mean ± SEM) in four groups: controls (n = 6), or puppies inoculated with both CPI2 and Bb (CPI2‐Bb) (n = 11), with only CPI2 (n = 4), or only Bb (n = 4). The puppies were killed 3–4 days after inoculation, the lungs excised, the intermediate lobe lavaged, and BALF and the bronchiolar wall tissue examined for neutrophils and other inflammatory cells. Control puppies had no evidence of inflammation. However, the CPI2‐Bb puppies had developed cough and rhinitis, positive cultures for CPI2 and Bb, and a neutrophilic cellular response in both the bronchioles and the BALF. Puppies inoculated with only CPI2 or Bb had milder illnesses and no significant bronchiolar and BALF neutrophilic response. For all groups, the severity of bronchiolar wall inflammation correlated with the total number of BALF inflammatory cells, and bronchiolar wall neutrophil counts correlated with the percentage of neutrophils in the BALF. The illness and the airway hyperresponsiveness observed in the CPI2‐Bb group were associated with airway neutrophilia. Our studies support the hypothesis that neutrophils are associated with airway dysfunction in this model, and the use of BALF to study the process." @default.
• W2144585073 created "2016-06-24" @default.
• W2144585073 creator A5031508840 @default.
• W2144585073 creator A5039375561 @default.
• W2144585073 creator A5046071246 @default.
• W2144585073 creator A5056568767 @default.
• W2144585073 creator A5063076862 @default.
• W2144585073 creator A5069707174 @default.
• W2144585073 creator A5072502973 @default.
• W2144585073 creator A5086864798 @default.
• W2144585073 date "1992-04-01" @default.
• W2144585073 modified "2023-10-16" @default.
• W2144585073 title "Bronchoalveolar lavage fluid cytology reflects airway inflammation in beagle puppies with acute bronchiolitis" @default.
• W2144585073 cites W182121550 @default.
• W2144585073 cites W1987674391 @default.
• W2144585073 cites W2032418350 @default.
• W2144585073 cites W2051395918 @default.
• W2144585073 cites W2087385789 @default.
• W2144585073 cites W2089217239 @default.
• W2144585073 cites W2091798765 @default.
• W2144585073 cites W2106220886 @default.
• W2144585073 cites W2107184899 @default.
• W2144585073 cites W2110503309 @default.
• W2144585073 cites W2121721745 @default.
• W2144585073 cites W2329211716 @default.
• W2144585073 cites W2413910094 @default.
• W2144585073 cites W4211036623 @default.
• W2144585073 cites W4341351 @default.
• W2144585073 cites W65262219 @default.
• W2144585073 doi "https://doi.org/10.1002/ppul.1950120404" @default.
• W2144585073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1319565" @default.
• W2144585073 hasPublicationYear "1992" @default.
• W2144585073 type Work @default.
• W2144585073 sameAs 2144585073 @default.
• W2144585073 citedByCount "7" @default.
• W2144585073 countsByYear W21445850732012 @default.
• W2144585073 countsByYear W21445850732014 @default.
• W2144585073 countsByYear W21445850732015 @default.
• W2144585073 countsByYear W21445850732019 @default.
• W2144585073 countsByYear W21445850732020 @default.
• W2144585073 crossrefType "journal-article" @default.
• W2144585073 hasAuthorship W2144585073A5031508840 @default.
• W2144585073 hasAuthorship W2144585073A5039375561 @default.
• W2144585073 hasAuthorship W2144585073A5046071246 @default.
• W2144585073 hasAuthorship W2144585073A5056568767 @default.
• W2144585073 hasAuthorship W2144585073A5063076862 @default.
• W2144585073 hasAuthorship W2144585073A5069707174 @default.
• W2144585073 hasAuthorship W2144585073A5072502973 @default.
• W2144585073 hasAuthorship W2144585073A5086864798 @default.
• W2144585073 hasConcept C126322002 @default.
• W2144585073 hasConcept C142724271 @default.
• W2144585073 hasConcept C203014093 @default.
• W2144585073 hasConcept C2522874641 @default.
• W2144585073 hasConcept C2776820430 @default.
• W2144585073 hasConcept C2776914184 @default.
• W2144585073 hasConcept C2777107318 @default.
• W2144585073 hasConcept C2777714996 @default.
• W2144585073 hasConcept C2777802486 @default.
• W2144585073 hasConcept C2777961210 @default.
• W2144585073 hasConcept C2778821649 @default.
• W2144585073 hasConcept C523546767 @default.
• W2144585073 hasConcept C54355233 @default.
• W2144585073 hasConcept C71924100 @default.
• W2144585073 hasConcept C86803240 @default.
• W2144585073 hasConceptScore W2144585073C126322002 @default.
• W2144585073 hasConceptScore W2144585073C142724271 @default.
• W2144585073 hasConceptScore W2144585073C203014093 @default.
• W2144585073 hasConceptScore W2144585073C2522874641 @default.
• W2144585073 hasConceptScore W2144585073C2776820430 @default.
• W2144585073 hasConceptScore W2144585073C2776914184 @default.
• W2144585073 hasConceptScore W2144585073C2777107318 @default.
• W2144585073 hasConceptScore W2144585073C2777714996 @default.
• W2144585073 hasConceptScore W2144585073C2777802486 @default.
• W2144585073 hasConceptScore W2144585073C2777961210 @default.
• W2144585073 hasConceptScore W2144585073C2778821649 @default.
• W2144585073 hasConceptScore W2144585073C523546767 @default.
• W2144585073 hasConceptScore W2144585073C54355233 @default.
• W2144585073 hasConceptScore W2144585073C71924100 @default.
• W2144585073 hasConceptScore W2144585073C86803240 @default.
• W2144585073 hasIssue "4" @default.
• W2144585073 hasLocation W21445850731 @default.
• W2144585073 hasLocation W21445850732 @default.
• W2144585073 hasOpenAccess W2144585073 @default.
• W2144585073 hasPrimaryLocation W21445850731 @default.
• W2144585073 hasRelatedWork W1966043026 @default.
• W2144585073 hasRelatedWork W1988185521 @default.
• W2144585073 hasRelatedWork W2027848803 @default.
• W2144585073 hasRelatedWork W2354875722 @default.
• W2144585073 hasRelatedWork W2378266540 @default.
• W2144585073 hasRelatedWork W2794887651 @default.
• W2144585073 hasRelatedWork W2801705758 @default.
• W2144585073 hasRelatedWork W3017874160 @default.
• W2144585073 hasRelatedWork W3163730466 @default.
• W2144585073 hasRelatedWork W4313386787 @default.
• W2144585073 hasVolume "12" @default.
• W2144585073 isParatext "false" @default.
• W2144585073 isRetracted "false" @default.
• W2144585073 magId "2144585073" @default.

• next