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• W2144697304 abstract "Les neuropathies périphériques paranéoplasqiues constituent un groupe hétérogène de neuropathie pour lesquelles un lien entre la neuropathie et le cancer n’a été démontré que dans quelques formes. Certaines neuropathies paranéoplasiques sont associées à un anticorps reconnaissant un antigène commun au système nerveux et à la tumeur. L’anticorps anti-Hu est le plus fréquent de ces anticorps et la neuronopathie sensitive subaiguë est la principale manifestation. Les neuropathies associées à l’anticorps anti-CV2 sont plus rares. Pour les autres formes de neuropathies, il n’y a pas de lien démontré. La fréquence des cancers y varie de 1 à 18 p. 100. Ces neuropathies incluent des neuropathies avec vasculite nerveuse, des neuropathies inflammatoires démyélinisantes, des neuropathies dysautonomiques et des maladies du motoneurone. Le traitement du cancer améliore parfois la neuropathie. Des données récentes suggèrent que des gangliosides puissent être la cible d’un processus auto-immun dans certaines neuropathies associées à des mélanomes. Paraneoplastic peripheral neuropathies constitute a heterogeneous group of conditions. A link between the tumor and the neuropathy has been demonstrated in a subgroup only. Definite paraneoplastic neuropathies correspond to neuropathies associated with antibodies reacting with antigens common to the peripheral nervous system and the cancer. Neuropathies associated with anti-Hu antibodies are the most frequent and consist mainly in subacute sensory neuronopathy. Sensory or sensory-motor neuropathies with anti-CV2 antibodies are less frequent. The link between the cancer and the neuropathy is less clear in the other forms. The frequency of cancer in this group varies from 1 to 18 p.cent.These neuropathies include inflammatory demyelinating neuropathies, neuropathy and vasculitis, lower motor neurone diseases, and autonomic neuropathies. Occasionally, the neuropathy improves with treatment of the tumor. Recent data suggest that gangliosides may be the target of the immune process in neuropathies associated with melanoma." @default.
• W2144697304 created "2016-06-24" @default.
• W2144697304 creator A5001830388 @default.
• W2144697304 creator A5082573307 @default.
• W2144697304 date "2004-02-01" @default.
• W2144697304 modified "2023-09-26" @default.
• W2144697304 title "Les neuropathies périphériques paranéoplasiques" @default.
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