FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144762330> ?p ?o ?g. }

• W2144762330 endingPage "581" @default.
• W2144762330 startingPage "576" @default.
• W2144762330 abstract "<b>Background:</b> Vasodilator stimulated phosphoprotein (VASP) is associated with focal adhesions and is thought to have an important role in actin filament assembly and cell motility. We hypothesise that an increase in the expression of VASP is involved in the progression and invasion of lung adenocarcinomas in parallel to tumour progression. A study was undertaken to analyse VASP expression in normal lung tissue and lung adenocarcinomas. <b>Methods:</b> Human lung tissues with adenocarcinomas (n = 26) were used. Normal lung tissue specimens (n = 14) were taken from areas a standard distance (3 cm) from resected adenocarcinomas of patients who underwent surgical lung resection. Adenocarcinomas were classified according to pathological staging and histopathological grades. Tissues were stained for VASP using immunohistochemistry. <b>Results:</b> Normal lung pneumocytes showed no VASP expression while alveolar macrophages had the strongest immunoreactivity for VASP. Bronchial epithelium (surface epithelium, goblet cells) and bronchial gland cells had a very weak immunoreactivity for VASP. Adenocarcinomas had significantly greater VASP expression than normal epithelium (p<0.001). Moreover, VASP expression in adenocarcinomas increased significantly with more advanced tumour stage (p<0.001). <b>Conclusions:</b> The spatial and differential expression of VASP in normal lung tissue and lung adenocarcinomas suggests that it is likely to be involved in the differentiation of normal lung cells to adenocarcinomas. The significant increase in the expression of VASP in adenocarcinomas in parallel to pathological staging suggests that it may regulate the invasive behaviour of lung adenocarcinomas as adenocarcinoma invasion is increased in more advanced tumours." @default.
• W2144762330 created "2016-06-24" @default.
• W2144762330 creator A5016377204 @default.
• W2144762330 creator A5032185915 @default.
• W2144762330 creator A5039749551 @default.
• W2144762330 creator A5048967190 @default.
• W2144762330 creator A5074006991 @default.
• W2144762330 creator A5077041535 @default.
• W2144762330 date "2005-07-01" @default.
• W2144762330 modified "2023-10-18" @default.
• W2144762330 title "Differential expression of VASP in normal lung tissue and lung adenocarcinomas" @default.
• W2144762330 cites W1967345709 @default.
• W2144762330 cites W1974766153 @default.
• W2144762330 cites W1977316223 @default.
• W2144762330 cites W1979491371 @default.
• W2144762330 cites W1979538859 @default.
• W2144762330 cites W1986260198 @default.
• W2144762330 cites W1993312546 @default.
• W2144762330 cites W2006223802 @default.
• W2144762330 cites W2012277412 @default.
• W2144762330 cites W2017501808 @default.
• W2144762330 cites W2019533876 @default.
• W2144762330 cites W2033553319 @default.
• W2144762330 cites W2046097023 @default.
• W2144762330 cites W2063168904 @default.
• W2144762330 cites W2079695285 @default.
• W2144762330 cites W2101124867 @default.
• W2144762330 cites W2102876507 @default.
• W2144762330 cites W2108496386 @default.
• W2144762330 cites W2109260416 @default.
• W2144762330 cites W2115210097 @default.
• W2144762330 cites W2115523048 @default.
• W2144762330 cites W2116862237 @default.
• W2144762330 cites W2138248262 @default.
• W2144762330 cites W2148668444 @default.
• W2144762330 cites W2151220251 @default.
• W2144762330 cites W2151651170 @default.
• W2144762330 cites W2152869893 @default.
• W2144762330 cites W2162158140 @default.
• W2144762330 cites W2171521898 @default.
• W2144762330 cites W2333684590 @default.
• W2144762330 cites W329913664 @default.
• W2144762330 cites W339678308 @default.
• W2144762330 doi "https://doi.org/10.1136/thx.2004.037622" @default.
• W2144762330 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1747468" @default.
• W2144762330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15994266" @default.
• W2144762330 hasPublicationYear "2005" @default.
• W2144762330 type Work @default.
• W2144762330 sameAs 2144762330 @default.
• W2144762330 citedByCount "46" @default.
• W2144762330 countsByYear W21447623302012 @default.
• W2144762330 countsByYear W21447623302013 @default.
• W2144762330 countsByYear W21447623302014 @default.
• W2144762330 countsByYear W21447623302015 @default.
• W2144762330 countsByYear W21447623302016 @default.
• W2144762330 countsByYear W21447623302017 @default.
• W2144762330 countsByYear W21447623302018 @default.
• W2144762330 countsByYear W21447623302019 @default.
• W2144762330 countsByYear W21447623302020 @default.
• W2144762330 countsByYear W21447623302021 @default.
• W2144762330 countsByYear W21447623302023 @default.
• W2144762330 crossrefType "journal-article" @default.
• W2144762330 hasAuthorship W2144762330A5016377204 @default.
• W2144762330 hasAuthorship W2144762330A5032185915 @default.
• W2144762330 hasAuthorship W2144762330A5039749551 @default.
• W2144762330 hasAuthorship W2144762330A5048967190 @default.
• W2144762330 hasAuthorship W2144762330A5074006991 @default.
• W2144762330 hasAuthorship W2144762330A5077041535 @default.
• W2144762330 hasBestOaLocation W21447623301 @default.
• W2144762330 hasConcept C121608353 @default.
• W2144762330 hasConcept C126322002 @default.
• W2144762330 hasConcept C142724271 @default.
• W2144762330 hasConcept C204232928 @default.
• W2144762330 hasConcept C2777714996 @default.
• W2144762330 hasConcept C2781182431 @default.
• W2144762330 hasConcept C529295009 @default.
• W2144762330 hasConcept C71924100 @default.
• W2144762330 hasConceptScore W2144762330C121608353 @default.
• W2144762330 hasConceptScore W2144762330C126322002 @default.
• W2144762330 hasConceptScore W2144762330C142724271 @default.
• W2144762330 hasConceptScore W2144762330C204232928 @default.
• W2144762330 hasConceptScore W2144762330C2777714996 @default.
• W2144762330 hasConceptScore W2144762330C2781182431 @default.
• W2144762330 hasConceptScore W2144762330C529295009 @default.
• W2144762330 hasConceptScore W2144762330C71924100 @default.
• W2144762330 hasIssue "7" @default.
• W2144762330 hasLocation W21447623301 @default.
• W2144762330 hasLocation W21447623302 @default.
• W2144762330 hasLocation W21447623303 @default.
• W2144762330 hasLocation W21447623304 @default.
• W2144762330 hasLocation W21447623305 @default.
• W2144762330 hasOpenAccess W2144762330 @default.
• W2144762330 hasPrimaryLocation W21447623301 @default.
• W2144762330 hasRelatedWork W1498202335 @default.
• W2144762330 hasRelatedWork W1651112321 @default.
• W2144762330 hasRelatedWork W1969927172 @default.
• W2144762330 hasRelatedWork W2054378706 @default.
• W2144762330 hasRelatedWork W2055479802 @default.

• next