Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144824933> ?p ?o ?g. }
- W2144824933 endingPage "936" @default.
- W2144824933 startingPage "927" @default.
- W2144824933 abstract "Genomic imprinting is an important regulatory mechanism that silences one of the parental copies of a gene. To systematically characterize this phenomenon, we analyze tissue specificity of imprinting from allelic expression data in 1582 primary tissue samples from 178 individuals from the Genotype-Tissue Expression (GTEx) project. We characterize imprinting in 42 genes, including both novel and previously identified genes. Tissue specificity of imprinting is widespread, and gender-specific effects are revealed in a small number of genes in muscle with stronger imprinting in males. IGF2 shows maternal expression in the brain instead of the canonical paternal expression elsewhere. Imprinting appears to have only a subtle impact on tissue-specific expression levels, with genes lacking a systematic expression difference between tissues with imprinted and biallelic expression. In summary, our systematic characterization of imprinting in adult tissues highlights variation in imprinting between genes, individuals, and tissues." @default.
- W2144824933 created "2016-06-24" @default.
- W2144824933 creator A5003038390 @default.
- W2144824933 creator A5004215664 @default.
- W2144824933 creator A5005988117 @default.
- W2144824933 creator A5016670347 @default.
- W2144824933 creator A5017737620 @default.
- W2144824933 creator A5018051251 @default.
- W2144824933 creator A5025409424 @default.
- W2144824933 creator A5037063981 @default.
- W2144824933 creator A5053239891 @default.
- W2144824933 creator A5054062020 @default.
- W2144824933 creator A5058484067 @default.
- W2144824933 creator A5064165945 @default.
- W2144824933 creator A5064582174 @default.
- W2144824933 creator A5067060534 @default.
- W2144824933 creator A5071708691 @default.
- W2144824933 creator A5073710029 @default.
- W2144824933 creator A5077383222 @default.
- W2144824933 creator A5078748158 @default.
- W2144824933 creator A5080971226 @default.
- W2144824933 creator A5084778350 @default.
- W2144824933 creator A5088861717 @default.
- W2144824933 creator A5090471536 @default.
- W2144824933 date "2015-05-07" @default.
- W2144824933 modified "2023-10-16" @default.
- W2144824933 title "The landscape of genomic imprinting across diverse adult human tissues" @default.
- W2144824933 cites W1533942137 @default.
- W2144824933 cites W1843990841 @default.
- W2144824933 cites W1873856147 @default.
- W2144824933 cites W1920306191 @default.
- W2144824933 cites W1964318976 @default.
- W2144824933 cites W1966231666 @default.
- W2144824933 cites W1976143235 @default.
- W2144824933 cites W1976274498 @default.
- W2144824933 cites W1976848056 @default.
- W2144824933 cites W1977459685 @default.
- W2144824933 cites W1978386737 @default.
- W2144824933 cites W1981005523 @default.
- W2144824933 cites W1988939568 @default.
- W2144824933 cites W1990626904 @default.
- W2144824933 cites W2001396320 @default.
- W2144824933 cites W2002963067 @default.
- W2144824933 cites W2005122856 @default.
- W2144824933 cites W2014143877 @default.
- W2144824933 cites W2025648894 @default.
- W2144824933 cites W2025943989 @default.
- W2144824933 cites W2036815225 @default.
- W2144824933 cites W2048336744 @default.
- W2144824933 cites W2050030583 @default.
- W2144824933 cites W2055550188 @default.
- W2144824933 cites W2060967135 @default.
- W2144824933 cites W2072999738 @default.
- W2144824933 cites W2074271561 @default.
- W2144824933 cites W2075805514 @default.
- W2144824933 cites W2081808783 @default.
- W2144824933 cites W2083479872 @default.
- W2144824933 cites W2092569327 @default.
- W2144824933 cites W2096791516 @default.
- W2144824933 cites W2097065948 @default.
- W2144824933 cites W2101549237 @default.
- W2144824933 cites W2103211527 @default.
- W2144824933 cites W2103421101 @default.
- W2144824933 cites W2103441770 @default.
- W2144824933 cites W2107951062 @default.
- W2144824933 cites W2113312463 @default.
- W2144824933 cites W2121744576 @default.
- W2144824933 cites W2128941208 @default.
- W2144824933 cites W2129246334 @default.
- W2144824933 cites W2130365449 @default.
- W2144824933 cites W2135311721 @default.
- W2144824933 cites W2141553269 @default.
- W2144824933 cites W2142933606 @default.
- W2144824933 cites W2148187752 @default.
- W2144824933 cites W2151051330 @default.
- W2144824933 cites W2151570787 @default.
- W2144824933 cites W2156431476 @default.
- W2144824933 cites W2157805276 @default.
- W2144824933 cites W2164283721 @default.
- W2144824933 cites W2166889662 @default.
- W2144824933 cites W2171005514 @default.
- W2144824933 cites W2171538603 @default.
- W2144824933 cites W2299839685 @default.
- W2144824933 doi "https://doi.org/10.1101/gr.192278.115" @default.
- W2144824933 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4484390" @default.
- W2144824933 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25953952" @default.
- W2144824933 hasPublicationYear "2015" @default.
- W2144824933 type Work @default.
- W2144824933 sameAs 2144824933 @default.
- W2144824933 citedByCount "181" @default.
- W2144824933 countsByYear W21448249332015 @default.
- W2144824933 countsByYear W21448249332016 @default.
- W2144824933 countsByYear W21448249332017 @default.
- W2144824933 countsByYear W21448249332018 @default.
- W2144824933 countsByYear W21448249332019 @default.
- W2144824933 countsByYear W21448249332020 @default.
- W2144824933 countsByYear W21448249332021 @default.
- W2144824933 countsByYear W21448249332022 @default.