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- W2144852012 endingPage "20140087" @default.
- W2144852012 startingPage "20140087" @default.
- W2144852012 abstract "In recent decades, the emergence and spread of antibiotic resistance among bacterial pathogens has become a major threat to public health. Bacteria can acquire antibiotic resistance genes by the mobilization and transfer of resistance genes from a donor strain. The human gut contains a densely populated microbial ecosystem, termed the gut microbiota, which offers ample opportunities for the horizontal transfer of genetic material, including antibiotic resistance genes. Recent technological advances allow microbiota-wide studies into the diversity and dynamics of the antibiotic resistance genes that are harboured by the gut microbiota ('the gut resistome'). Genes conferring resistance to antibiotics are ubiquitously present among the gut microbiota of humans and most resistance genes are harboured by strictly anaerobic gut commensals. The horizontal transfer of genetic material, including antibiotic resistance genes, through conjugation and transduction is a frequent event in the gut microbiota, but mostly involves non-pathogenic gut commensals as these dominate the microbiota of healthy individuals. Resistance gene transfer from commensals to gut-dwelling opportunistic pathogens appears to be a relatively rare event but may contribute to the emergence of multi-drug resistant strains, as is illustrated by the vancomycin resistance determinants that are shared by anaerobic gut commensals and the nosocomial pathogen Enterococcus faecium." @default.
- W2144852012 created "2016-06-24" @default.
- W2144852012 creator A5024002499 @default.
- W2144852012 date "2015-06-05" @default.
- W2144852012 modified "2023-10-14" @default.
- W2144852012 title "The human gut resistome" @default.
- W2144852012 cites W100864707 @default.
- W2144852012 cites W1760389142 @default.
- W2144852012 cites W1825642470 @default.
- W2144852012 cites W1929185253 @default.
- W2144852012 cites W1964071916 @default.
- W2144852012 cites W1964640602 @default.
- W2144852012 cites W1967617413 @default.
- W2144852012 cites W1973056259 @default.
- W2144852012 cites W1976667730 @default.
- W2144852012 cites W1982073117 @default.
- W2144852012 cites W1985543936 @default.
- W2144852012 cites W1985716049 @default.
- W2144852012 cites W1988631277 @default.
- W2144852012 cites W1989179901 @default.
- W2144852012 cites W1990152860 @default.
- W2144852012 cites W1993043587 @default.
- W2144852012 cites W1997756678 @default.
- W2144852012 cites W1999699598 @default.
- W2144852012 cites W2005377507 @default.
- W2144852012 cites W2006995996 @default.
- W2144852012 cites W2008274231 @default.
- W2144852012 cites W2011297553 @default.
- W2144852012 cites W2011482814 @default.
- W2144852012 cites W2012372156 @default.
- W2144852012 cites W2027951608 @default.
- W2144852012 cites W2032605132 @default.
- W2144852012 cites W2033002674 @default.
- W2144852012 cites W2033617629 @default.
- W2144852012 cites W2034806366 @default.
- W2144852012 cites W2041543427 @default.
- W2144852012 cites W2043442946 @default.
- W2144852012 cites W2048676453 @default.
- W2144852012 cites W2051267230 @default.
- W2144852012 cites W2057710367 @default.
- W2144852012 cites W2063114050 @default.
- W2144852012 cites W2065088137 @default.
- W2144852012 cites W2071718874 @default.
- W2144852012 cites W2072706491 @default.
- W2144852012 cites W2073342853 @default.
- W2144852012 cites W2073703928 @default.
- W2144852012 cites W2076505260 @default.
- W2144852012 cites W2079901010 @default.
- W2144852012 cites W2084646638 @default.
- W2144852012 cites W2084814249 @default.
- W2144852012 cites W2093401639 @default.
- W2144852012 cites W2095158284 @default.
- W2144852012 cites W2098980360 @default.
- W2144852012 cites W2099673297 @default.
- W2144852012 cites W2099837668 @default.
- W2144852012 cites W2103784576 @default.
- W2144852012 cites W2104371716 @default.
- W2144852012 cites W2104688104 @default.
- W2144852012 cites W2105580456 @default.
- W2144852012 cites W2105914104 @default.
- W2144852012 cites W2108638835 @default.
- W2144852012 cites W2109371724 @default.
- W2144852012 cites W2110235509 @default.
- W2144852012 cites W2112612986 @default.
- W2144852012 cites W2113885639 @default.
- W2144852012 cites W2114460946 @default.
- W2144852012 cites W2118253093 @default.
- W2144852012 cites W2118688136 @default.
- W2144852012 cites W2126295648 @default.
- W2144852012 cites W2128769815 @default.
- W2144852012 cites W2128820093 @default.
- W2144852012 cites W2131781913 @default.
- W2144852012 cites W2131919079 @default.
- W2144852012 cites W2134180244 @default.
- W2144852012 cites W2134852597 @default.
- W2144852012 cites W2136711150 @default.
- W2144852012 cites W2137195441 @default.
- W2144852012 cites W2137489399 @default.
- W2144852012 cites W2144241990 @default.
- W2144852012 cites W2145537580 @default.
- W2144852012 cites W2149351690 @default.
- W2144852012 cites W2150842398 @default.
- W2144852012 cites W2151450070 @default.
- W2144852012 cites W2153683423 @default.
- W2144852012 cites W2154179335 @default.
- W2144852012 cites W2154603562 @default.
- W2144852012 cites W2155867629 @default.
- W2144852012 cites W2161251845 @default.
- W2144852012 cites W2164839921 @default.
- W2144852012 cites W2165003751 @default.
- W2144852012 cites W2168183873 @default.
- W2144852012 cites W2168519960 @default.
- W2144852012 cites W2168870245 @default.
- W2144852012 cites W2328023807 @default.
- W2144852012 doi "https://doi.org/10.1098/rstb.2014.0087" @default.
- W2144852012 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4424436" @default.
- W2144852012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25918444" @default.
- W2144852012 hasPublicationYear "2015" @default.