FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2144927401> ?p ?o ?g. }

• W2144927401 endingPage "299" @default.
• W2144927401 startingPage "299" @default.
• W2144927401 abstract "Background Rapid point-of-care tests (POCTs) for chlamydia (Chlamydia trachomatis) and gonorrhoea (Neisseria gonorrhoeae) have the potential to confer health benefits in certain populations even at moderate sensitivities; however, suitable POCTs for these organisms are currently lacking. Methods: In this study, we investigated the use of direct urine polymerase chain reaction (PCR), with the view of implementing a simplified PCR strategy for high-throughput chlamydia and gonorrhoea screening in remote settings. Briefly, a simple dilution of the urine was performed before adding it directly to a real-time PCR reaction. The method was evaluated using 134 stored urine specimens that had been submitted for chlamydia and gonorrhoea testing and had been tested using a commercial C. trachomatis and N. gonorrhoeae PCR method. These included samples that were PCR-positive for chlamydia (n = 87), gonorrhoea (n = 16) or both (n = 2). Direct urine testing was conducted using previously described in-house real-time PCR methods for C. trachomatis and N. gonorrhoeae as well as for recognised N.gonorrhoeae antimicrobial resistance mechanisms. Results: The overall sensitivities and specificities of the direct urine PCR were 78% and 100% for chlamydia, and 83% and 100% for gonorrhoea. N.gonorrhoeae penicillin and quinolone resistance mechanisms were characterised in 14 of the 18 N. gonorrhoeae-positive samples. Conclusions: The results of this study show that the simplified PCR strategy may be a feasible approach for rapid screening and improving chlamydia and gonorrhoea treatment in remote settings." @default.
• W2144927401 created "2016-06-24" @default.
• W2144927401 creator A5005605684 @default.
• W2144927401 creator A5006994900 @default.
• W2144927401 creator A5014483955 @default.
• W2144927401 creator A5052981616 @default.
• W2144927401 creator A5056238281 @default.
• W2144927401 creator A5058433545 @default.
• W2144927401 creator A5065984680 @default.
• W2144927401 creator A5079591035 @default.
• W2144927401 date "2013-01-01" @default.
• W2144927401 modified "2023-09-27" @default.
• W2144927401 title "Direct urine polymerase chain reaction for chlamydia and gonorrhoea: a simple means of bringing high-throughput rapid testing to remote settings?" @default.
• W2144927401 cites W1967734685 @default.
• W2144927401 cites W1968533143 @default.
• W2144927401 cites W1975828116 @default.
• W2144927401 cites W1992160535 @default.
• W2144927401 cites W1999690562 @default.
• W2144927401 cites W2033574850 @default.
• W2144927401 cites W2033805746 @default.
• W2144927401 cites W2034641183 @default.
• W2144927401 cites W2071722704 @default.
• W2144927401 cites W2080245071 @default.
• W2144927401 cites W2133852833 @default.
• W2144927401 cites W2141012160 @default.
• W2144927401 cites W2148929213 @default.
• W2144927401 cites W2151815083 @default.
• W2144927401 cites W2152538368 @default.
• W2144927401 cites W2152879488 @default.
• W2144927401 cites W2163631154 @default.
• W2144927401 cites W2168743608 @default.
• W2144927401 doi "https://doi.org/10.1071/sh12108" @default.
• W2144927401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23639791" @default.
• W2144927401 hasPublicationYear "2013" @default.
• W2144927401 type Work @default.
• W2144927401 sameAs 2144927401 @default.
• W2144927401 citedByCount "1" @default.
• W2144927401 countsByYear W21449274012020 @default.
• W2144927401 crossrefType "journal-article" @default.
• W2144927401 hasAuthorship W2144927401A5005605684 @default.
• W2144927401 hasAuthorship W2144927401A5006994900 @default.
• W2144927401 hasAuthorship W2144927401A5014483955 @default.
• W2144927401 hasAuthorship W2144927401A5052981616 @default.
• W2144927401 hasAuthorship W2144927401A5056238281 @default.
• W2144927401 hasAuthorship W2144927401A5058433545 @default.
• W2144927401 hasAuthorship W2144927401A5065984680 @default.
• W2144927401 hasAuthorship W2144927401A5079591035 @default.
• W2144927401 hasConcept C104317684 @default.
• W2144927401 hasConcept C126322002 @default.
• W2144927401 hasConcept C159047783 @default.
• W2144927401 hasConcept C203014093 @default.
• W2144927401 hasConcept C2776983459 @default.
• W2144927401 hasConcept C2777038808 @default.
• W2144927401 hasConcept C2777391075 @default.
• W2144927401 hasConcept C2778082588 @default.
• W2144927401 hasConcept C2778651837 @default.
• W2144927401 hasConcept C2779166590 @default.
• W2144927401 hasConcept C2780026642 @default.
• W2144927401 hasConcept C2780122209 @default.
• W2144927401 hasConcept C2909760446 @default.
• W2144927401 hasConcept C3013748606 @default.
• W2144927401 hasConcept C48023723 @default.
• W2144927401 hasConcept C49105822 @default.
• W2144927401 hasConcept C501593827 @default.
• W2144927401 hasConcept C55493867 @default.
• W2144927401 hasConcept C71924100 @default.
• W2144927401 hasConcept C86803240 @default.
• W2144927401 hasConcept C89423630 @default.
• W2144927401 hasConcept C94665300 @default.
• W2144927401 hasConceptScore W2144927401C104317684 @default.
• W2144927401 hasConceptScore W2144927401C126322002 @default.
• W2144927401 hasConceptScore W2144927401C159047783 @default.
• W2144927401 hasConceptScore W2144927401C203014093 @default.
• W2144927401 hasConceptScore W2144927401C2776983459 @default.
• W2144927401 hasConceptScore W2144927401C2777038808 @default.
• W2144927401 hasConceptScore W2144927401C2777391075 @default.
• W2144927401 hasConceptScore W2144927401C2778082588 @default.
• W2144927401 hasConceptScore W2144927401C2778651837 @default.
• W2144927401 hasConceptScore W2144927401C2779166590 @default.
• W2144927401 hasConceptScore W2144927401C2780026642 @default.
• W2144927401 hasConceptScore W2144927401C2780122209 @default.
• W2144927401 hasConceptScore W2144927401C2909760446 @default.
• W2144927401 hasConceptScore W2144927401C3013748606 @default.
• W2144927401 hasConceptScore W2144927401C48023723 @default.
• W2144927401 hasConceptScore W2144927401C49105822 @default.
• W2144927401 hasConceptScore W2144927401C501593827 @default.
• W2144927401 hasConceptScore W2144927401C55493867 @default.
• W2144927401 hasConceptScore W2144927401C71924100 @default.
• W2144927401 hasConceptScore W2144927401C86803240 @default.
• W2144927401 hasConceptScore W2144927401C89423630 @default.
• W2144927401 hasConceptScore W2144927401C94665300 @default.
• W2144927401 hasIssue "4" @default.
• W2144927401 hasLocation W21449274011 @default.
• W2144927401 hasLocation W21449274012 @default.
• W2144927401 hasOpenAccess W2144927401 @default.
• W2144927401 hasPrimaryLocation W21449274011 @default.
• W2144927401 hasRelatedWork W1606576481 @default.
• W2144927401 hasRelatedWork W1964120244 @default.

• next