Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145118226> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2145118226 endingPage "256" @default.
- W2145118226 startingPage "250" @default.
- W2145118226 abstract "Direct visualization of the events resulting from LPS stimulation of mouse spleen cells in vitro was achieved by characterizing the cells during four days of culture for morphology, Ig and theta surface markers and autoradiography after [3H] thymidine uptake. The changes observed were related to biochemical parameters such as incorporation of [3H] thymidine into DNA, Ig biosynthesis and secretion. Two pathways of B lymphocyte differentiation were observed: a) the generation of a large number of small B lymphocytes with high density of surface Ig but no internal pool detectable by immunofluorescence, and b) the maturation of a very small proportion of cells with a large intracellular pool and the ability to secrete Ig. Both cell types arise from dividing blast cells, either physically separated or traced by pulse chase experiments with [3H] thymidine. We discuss whether this duality is caused by the triggering of different B cell subpopulations at different developmental stages, preprogramed to one or the other pathway or whether the final direction of development depends on the microenvironment of individual dividing cells." @default.
- W2145118226 created "2016-06-24" @default.
- W2145118226 creator A5020299492 @default.
- W2145118226 creator A5026368676 @default.
- W2145118226 creator A5060464846 @default.
- W2145118226 creator A5085165499 @default.
- W2145118226 date "1976-04-01" @default.
- W2145118226 modified "2023-09-23" @default.
- W2145118226 title "Dual pathway of B lymphocyte differentiationin vitro" @default.
- W2145118226 cites W1966245246 @default.
- W2145118226 cites W1969031871 @default.
- W2145118226 cites W1974929788 @default.
- W2145118226 cites W1986737017 @default.
- W2145118226 cites W1996741191 @default.
- W2145118226 cites W2012757734 @default.
- W2145118226 cites W2022418117 @default.
- W2145118226 cites W2023385280 @default.
- W2145118226 cites W2036892733 @default.
- W2145118226 cites W2038790596 @default.
- W2145118226 cites W2039729853 @default.
- W2145118226 cites W2043696891 @default.
- W2145118226 cites W2050443635 @default.
- W2145118226 cites W2062581415 @default.
- W2145118226 cites W2093896313 @default.
- W2145118226 cites W2106826368 @default.
- W2145118226 cites W2112009257 @default.
- W2145118226 cites W2117072801 @default.
- W2145118226 cites W2119410840 @default.
- W2145118226 cites W2120805766 @default.
- W2145118226 cites W2137783265 @default.
- W2145118226 cites W2152703642 @default.
- W2145118226 cites W2169102863 @default.
- W2145118226 doi "https://doi.org/10.1002/eji.1830060404" @default.
- W2145118226 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/791655" @default.
- W2145118226 hasPublicationYear "1976" @default.
- W2145118226 type Work @default.
- W2145118226 sameAs 2145118226 @default.
- W2145118226 citedByCount "22" @default.
- W2145118226 crossrefType "journal-article" @default.
- W2145118226 hasAuthorship W2145118226A5020299492 @default.
- W2145118226 hasAuthorship W2145118226A5026368676 @default.
- W2145118226 hasAuthorship W2145118226A5060464846 @default.
- W2145118226 hasAuthorship W2145118226A5085165499 @default.
- W2145118226 hasConcept C134018914 @default.
- W2145118226 hasConcept C153911025 @default.
- W2145118226 hasConcept C202751555 @default.
- W2145118226 hasConcept C203014093 @default.
- W2145118226 hasConcept C24998067 @default.
- W2145118226 hasConcept C2777108182 @default.
- W2145118226 hasConcept C2777761686 @default.
- W2145118226 hasConcept C2780931953 @default.
- W2145118226 hasConcept C49039625 @default.
- W2145118226 hasConcept C55493867 @default.
- W2145118226 hasConcept C64241487 @default.
- W2145118226 hasConcept C79879829 @default.
- W2145118226 hasConcept C86803240 @default.
- W2145118226 hasConcept C95444343 @default.
- W2145118226 hasConceptScore W2145118226C134018914 @default.
- W2145118226 hasConceptScore W2145118226C153911025 @default.
- W2145118226 hasConceptScore W2145118226C202751555 @default.
- W2145118226 hasConceptScore W2145118226C203014093 @default.
- W2145118226 hasConceptScore W2145118226C24998067 @default.
- W2145118226 hasConceptScore W2145118226C2777108182 @default.
- W2145118226 hasConceptScore W2145118226C2777761686 @default.
- W2145118226 hasConceptScore W2145118226C2780931953 @default.
- W2145118226 hasConceptScore W2145118226C49039625 @default.
- W2145118226 hasConceptScore W2145118226C55493867 @default.
- W2145118226 hasConceptScore W2145118226C64241487 @default.
- W2145118226 hasConceptScore W2145118226C79879829 @default.
- W2145118226 hasConceptScore W2145118226C86803240 @default.
- W2145118226 hasConceptScore W2145118226C95444343 @default.
- W2145118226 hasIssue "4" @default.
- W2145118226 hasLocation W21451182261 @default.
- W2145118226 hasLocation W21451182262 @default.
- W2145118226 hasOpenAccess W2145118226 @default.
- W2145118226 hasPrimaryLocation W21451182261 @default.
- W2145118226 hasRelatedWork W120480787 @default.
- W2145118226 hasRelatedWork W1502619023 @default.
- W2145118226 hasRelatedWork W2014469491 @default.
- W2145118226 hasRelatedWork W2059655161 @default.
- W2145118226 hasRelatedWork W2069316307 @default.
- W2145118226 hasRelatedWork W2091660719 @default.
- W2145118226 hasRelatedWork W2328939514 @default.
- W2145118226 hasRelatedWork W2399092402 @default.
- W2145118226 hasRelatedWork W2441690865 @default.
- W2145118226 hasRelatedWork W2460662519 @default.
- W2145118226 hasVolume "6" @default.
- W2145118226 isParatext "false" @default.
- W2145118226 isRetracted "false" @default.
- W2145118226 magId "2145118226" @default.
- W2145118226 workType "article" @default.