Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145206543> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2145206543 endingPage "118" @default.
- W2145206543 startingPage "105" @default.
- W2145206543 abstract "Etiological factors for gastric cancer, among others, involve consumption of smoked, salted, and pickled fish of certain types. Their chemical nature is not yet fully established but probably involves diazo phenols, and their formation can be prevented either by omitting the salting and pickling process, or by using vitamins C and E on the food prior to salting, pickling, or smoking. Both preventive approaches would limit the formation of mutagenic and carcinogenic diazo phenols. Sugimura and associates discovered new types of mutagens as heterocyclic amines that are formed during frying or broiling of meats and fish. In rats, these amines induce cancer specifically in organs such as breast, colon, or pancreas, associated with Western-type nutrition where promotional elements such as dietary fat play an enhancing role. Thus, inhibition of the formation of these new carcinogens during cooking would remove the genotoxic components from the diet. Mixing 10% soy protein with ground meat prior to frying prevents the formation of these mutagens presumably by affording a lower surface temperature. More effective is the addition of tryptophan, proline, or mixtures thereof, which specifically blocks the formation of these mutagens/carcinogens, probably by competing for reactive intermediary aldehydes, so that these cannot interact with the normal essential target, creatinine. Thus, we have available practical, yet science-based, mechanistically understood procedures to prevent the formation of carcinogens associated with important types of cancer prevalent in many countries.KeywordsGastric CancerHeterocyclic AmineBile Acid ConcentrationSalted FoodGround MeatThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
- W2145206543 created "2016-06-24" @default.
- W2145206543 creator A5005263678 @default.
- W2145206543 creator A5035630844 @default.
- W2145206543 date "1990-01-01" @default.
- W2145206543 modified "2023-09-24" @default.
- W2145206543 title "Prevention of Formation of Important Mutagens/Carcinogens in the Human Food Chain" @default.
- W2145206543 cites W1502825258 @default.
- W2145206543 cites W1877917243 @default.
- W2145206543 cites W1947380675 @default.
- W2145206543 cites W1966692190 @default.
- W2145206543 cites W1975159169 @default.
- W2145206543 cites W1977381688 @default.
- W2145206543 cites W1982076372 @default.
- W2145206543 cites W1983141235 @default.
- W2145206543 cites W1983704682 @default.
- W2145206543 cites W2001171973 @default.
- W2145206543 cites W2005156172 @default.
- W2145206543 cites W2005833435 @default.
- W2145206543 cites W2016763464 @default.
- W2145206543 cites W2017965261 @default.
- W2145206543 cites W2021166541 @default.
- W2145206543 cites W2022288992 @default.
- W2145206543 cites W2023381942 @default.
- W2145206543 cites W2025934349 @default.
- W2145206543 cites W2026493569 @default.
- W2145206543 cites W2032468865 @default.
- W2145206543 cites W2040076376 @default.
- W2145206543 cites W2040220083 @default.
- W2145206543 cites W2040755304 @default.
- W2145206543 cites W2041451987 @default.
- W2145206543 cites W2045092705 @default.
- W2145206543 cites W2047742774 @default.
- W2145206543 cites W2048352197 @default.
- W2145206543 cites W2049640173 @default.
- W2145206543 cites W2051241741 @default.
- W2145206543 cites W2055319066 @default.
- W2145206543 cites W2063941099 @default.
- W2145206543 cites W2064725119 @default.
- W2145206543 cites W2069358743 @default.
- W2145206543 cites W2087837945 @default.
- W2145206543 cites W2170418159 @default.
- W2145206543 cites W2322213171 @default.
- W2145206543 cites W2416108312 @default.
- W2145206543 doi "https://doi.org/10.1007/978-1-4615-9561-8_8" @default.
- W2145206543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2183763" @default.
- W2145206543 hasPublicationYear "1990" @default.
- W2145206543 type Work @default.
- W2145206543 sameAs 2145206543 @default.
- W2145206543 citedByCount "4" @default.
- W2145206543 crossrefType "book-chapter" @default.
- W2145206543 hasAuthorship W2145206543A5005263678 @default.
- W2145206543 hasAuthorship W2145206543A5035630844 @default.
- W2145206543 hasConcept C114246631 @default.
- W2145206543 hasConcept C185592680 @default.
- W2145206543 hasConcept C2909208804 @default.
- W2145206543 hasConcept C31903555 @default.
- W2145206543 hasConcept C505870484 @default.
- W2145206543 hasConcept C55493867 @default.
- W2145206543 hasConcept C86803240 @default.
- W2145206543 hasConceptScore W2145206543C114246631 @default.
- W2145206543 hasConceptScore W2145206543C185592680 @default.
- W2145206543 hasConceptScore W2145206543C2909208804 @default.
- W2145206543 hasConceptScore W2145206543C31903555 @default.
- W2145206543 hasConceptScore W2145206543C505870484 @default.
- W2145206543 hasConceptScore W2145206543C55493867 @default.
- W2145206543 hasConceptScore W2145206543C86803240 @default.
- W2145206543 hasLocation W21452065431 @default.
- W2145206543 hasLocation W21452065432 @default.
- W2145206543 hasOpenAccess W2145206543 @default.
- W2145206543 hasPrimaryLocation W21452065431 @default.
- W2145206543 hasRelatedWork W1989193297 @default.
- W2145206543 hasRelatedWork W2014090647 @default.
- W2145206543 hasRelatedWork W2029775051 @default.
- W2145206543 hasRelatedWork W2029862005 @default.
- W2145206543 hasRelatedWork W2103509317 @default.
- W2145206543 hasRelatedWork W2290977816 @default.
- W2145206543 hasRelatedWork W2369941557 @default.
- W2145206543 hasRelatedWork W925611091 @default.
- W2145206543 hasRelatedWork W2496978074 @default.
- W2145206543 hasRelatedWork W2497504283 @default.
- W2145206543 isParatext "false" @default.
- W2145206543 isRetracted "false" @default.
- W2145206543 magId "2145206543" @default.
- W2145206543 workType "book-chapter" @default.