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- W2145235302 abstract "Deep vein thrombosis is associated with a risk of pulmonary embolism and post thrombotic syndrome (PTS).Selective literature review with special reference to the American College of Chest Physicians' current guidelines and the German S2 interdisciplinary guideline.The most important therapeutic measure is prompt and adequate anticoagulation with heparin or fondaparinux. Thrombolysis or thrombectomy is only indicated in highly selected severe cases. The risk of PTS can be reduced by immediate ongoing treatment with compression stockings. Prevention of relapse is achieved using vitamin K antagonists with a target INR of 2.0 to 3.0. The duration of anticoagulation should be tailored to the localisation and etiology of the thrombosis, from at least three months to indefinite treatment. The ongoing risk of bleeding secondary to anticoagulation should be reevaluated at regular intervals as a cost-benefit analysis. New anticoagulants for acute and long term treatment will soon be available for clinical use." @default.
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- W2145235302 date "2008-01-07" @default.
- W2145235302 modified "2023-10-17" @default.
- W2145235302 title "The Treatment of Deep Vein Thrombosis in the Pelvis and Leg" @default.
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- W2145235302 doi "https://doi.org/10.3238/arztebl.2008.0025" @default.
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