FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145317218> ?p ?o ?g. }

• W2145317218 endingPage "7290.2012.00035" @default.
• W2145317218 startingPage "7290.2012.00035" @default.
• W2145317218 abstract "Transplantation of neural stem cells (NSCs) has been proposed as a treatment for Parkinson disease (PD). The aim of this study was to monitor the viability of transplanted NSCs expressing the enhanced luciferase gene in a mouse model of PD in vivo. The PD animal model was induced by unilateral injection of 6-hydroxydopamine (6-OHDA). The behavioral test using apomorphine-induced rotation and positron emission tomography with [18F]N-(3-fluoropropyl)-2′-carbomethoxy-3′-(4-iodophenyl)nortropane ([18F]FP-CIT) were conducted. HB1.F3 cells transduced with an enhanced firefly luciferase retroviral vector (F3-effLuc cells) were transplanted into the right striatum. In vivo bioluminescence imaging was repeated for 2 weeks. Four weeks after transplantation, [18F]FP-CIT PET and the rotation test were repeated. All 6-OHDA-injected mice showed markedly decreased [18F]FP-CIT uptake in the right striatum. Transplanted F3-effLuc cells were visualized on the right side of the brain in all mice by bioluminescence imaging. The bioluminescence intensity of the transplanted F3-effLuc cells gradually decreased until it was undetectable by 10 days. The behavioral test showed that stem cell transplantation attenuated the motor symptoms of PD. No significant change was found in [18F]FP-CIT imaging after cell transplantation. We successfully established an in vivo bioluminescence imaging system for the detection of transplanted NSCs in a mouse model of PD. NSC transplantation induced behavioral improvement in PD model mice." @default.
• W2145317218 created "2016-06-24" @default.
• W2145317218 creator A5013171066 @default.
• W2145317218 creator A5015351108 @default.
• W2145317218 creator A5031590094 @default.
• W2145317218 creator A5035478166 @default.
• W2145317218 creator A5040109906 @default.
• W2145317218 creator A5046812858 @default.
• W2145317218 creator A5047009175 @default.
• W2145317218 creator A5057249194 @default.
• W2145317218 creator A5067428277 @default.
• W2145317218 creator A5073284312 @default.
• W2145317218 creator A5081422038 @default.
• W2145317218 date "2013-06-01" @default.
• W2145317218 modified "2023-10-18" @default.
• W2145317218 title "In Vivo Visualization and Monitoring of Viable Neural Stem Cells Using Noninvasive Bioluminescence Imaging in the 6-Hydroxydopamine-Induced Mouse Model of Parkinson Disease" @default.
• W2145317218 cites W1874219366 @default.
• W2145317218 cites W1992618202 @default.
• W2145317218 cites W1996979123 @default.
• W2145317218 cites W2007532980 @default.
• W2145317218 cites W2011883029 @default.
• W2145317218 cites W2019935461 @default.
• W2145317218 cites W2022957248 @default.
• W2145317218 cites W2026881390 @default.
• W2145317218 cites W2051816916 @default.
• W2145317218 cites W2053850374 @default.
• W2145317218 cites W2065000444 @default.
• W2145317218 cites W2077999133 @default.
• W2145317218 cites W2087853632 @default.
• W2145317218 cites W2089829388 @default.
• W2145317218 cites W2097898942 @default.
• W2145317218 cites W2103612759 @default.
• W2145317218 cites W2104793567 @default.
• W2145317218 cites W2110432682 @default.
• W2145317218 cites W2138462240 @default.
• W2145317218 cites W2141373720 @default.
• W2145317218 cites W2147015050 @default.
• W2145317218 cites W2149262494 @default.
• W2145317218 cites W2152009823 @default.
• W2145317218 cites W2154755377 @default.
• W2145317218 cites W2168432509 @default.
• W2145317218 cites W2334461448 @default.
• W2145317218 cites W2397783496 @default.
• W2145317218 cites W37005 @default.
• W2145317218 cites W49996880 @default.
• W2145317218 doi "https://doi.org/10.2310/7290.2012.00035" @default.
• W2145317218 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23651500" @default.
• W2145317218 hasPublicationYear "2013" @default.
• W2145317218 type Work @default.
• W2145317218 sameAs 2145317218 @default.
• W2145317218 citedByCount "9" @default.
• W2145317218 countsByYear W21453172182014 @default.
• W2145317218 countsByYear W21453172182015 @default.
• W2145317218 countsByYear W21453172182016 @default.
• W2145317218 countsByYear W21453172182019 @default.
• W2145317218 countsByYear W21453172182023 @default.
• W2145317218 crossrefType "journal-article" @default.
• W2145317218 hasAuthorship W2145317218A5013171066 @default.
• W2145317218 hasAuthorship W2145317218A5015351108 @default.
• W2145317218 hasAuthorship W2145317218A5031590094 @default.
• W2145317218 hasAuthorship W2145317218A5035478166 @default.
• W2145317218 hasAuthorship W2145317218A5040109906 @default.
• W2145317218 hasAuthorship W2145317218A5046812858 @default.
• W2145317218 hasAuthorship W2145317218A5047009175 @default.
• W2145317218 hasAuthorship W2145317218A5057249194 @default.
• W2145317218 hasAuthorship W2145317218A5067428277 @default.
• W2145317218 hasAuthorship W2145317218A5073284312 @default.
• W2145317218 hasAuthorship W2145317218A5081422038 @default.
• W2145317218 hasBestOaLocation W21453172181 @default.
• W2145317218 hasConcept C111335760 @default.
• W2145317218 hasConcept C126322002 @default.
• W2145317218 hasConcept C136834591 @default.
• W2145317218 hasConcept C137183658 @default.
• W2145317218 hasConcept C142724271 @default.
• W2145317218 hasConcept C150903083 @default.
• W2145317218 hasConcept C161997846 @default.
• W2145317218 hasConcept C169760540 @default.
• W2145317218 hasConcept C185592680 @default.
• W2145317218 hasConcept C207001950 @default.
• W2145317218 hasConcept C26291073 @default.
• W2145317218 hasConcept C2777525119 @default.
• W2145317218 hasConcept C2779134260 @default.
• W2145317218 hasConcept C2779734285 @default.
• W2145317218 hasConcept C2780062018 @default.
• W2145317218 hasConcept C28328180 @default.
• W2145317218 hasConcept C2911016594 @default.
• W2145317218 hasConcept C2911091166 @default.
• W2145317218 hasConcept C29331040 @default.
• W2145317218 hasConcept C513476851 @default.
• W2145317218 hasConcept C5176359 @default.
• W2145317218 hasConcept C54009773 @default.
• W2145317218 hasConcept C54355233 @default.
• W2145317218 hasConcept C55493867 @default.
• W2145317218 hasConcept C71924100 @default.
• W2145317218 hasConcept C81885089 @default.
• W2145317218 hasConcept C86803240 @default.
• W2145317218 hasConcept C95444343 @default.
• W2145317218 hasConceptScore W2145317218C111335760 @default.

• next