Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145396554> ?p ?o ?g. }
- W2145396554 endingPage "988" @default.
- W2145396554 startingPage "979" @default.
- W2145396554 abstract "We report a comparison of worldwide genetic variation among 255 individuals by using autosomal, mitochondrial, and Y-chromosome polymorphisms. Variation is assessed by use of 30 autosomal restriction-site polymorphisms (RSPs), 60 autosomal short-tandem-repeat polymorphisms (STRPs), 13 Alu-insertion polymorphisms and one LINE-1 element, 611 bp of mitochondrial control-region sequence, and 10 Y-chromosome polymorphisms. Analysis of these data reveals substantial congruity among this diverse array of genetic systems. With the exception of the autosomal RSPs, in which an ascertainment bias exists, all systems show greater gene diversity in Africans than in either Europeans or Asians. Africans also have the largest total number of alleles, as well as the largest number of unique alleles, for most systems. GST values are 11%-18% for the autosomal systems and are two to three times higher for the mtDNA sequence and Y-chromosome RSPs. This difference is expected because of the lower effective population size of mtDNA and Y chromosomes. A lower value is seen for Y-chromosome STRs, reflecting a relative lack of continental population structure, as a result of rapid mutation and genetic drift. Africa has higher GST values than does either Europe or Asia for all systems except the Y-chromosome STRs and Alus. All systems except the Y-chromosome STRs show less variation between populations within continents than between continents. These results are reassuring in their consistency and offer broad support for an African origin of modern human populations." @default.
- W2145396554 created "2016-06-24" @default.
- W2145396554 creator A5025759265 @default.
- W2145396554 creator A5048181679 @default.
- W2145396554 creator A5064174809 @default.
- W2145396554 creator A5071157652 @default.
- W2145396554 creator A5074117254 @default.
- W2145396554 creator A5087469756 @default.
- W2145396554 creator A5090698697 @default.
- W2145396554 date "2000-03-01" @default.
- W2145396554 modified "2023-10-14" @default.
- W2145396554 title "The Distribution of Human Genetic Diversity: A Comparison of Mitochondrial, Autosomal, and Y-Chromosome Data" @default.
- W2145396554 cites W1508331931 @default.
- W2145396554 cites W1516569903 @default.
- W2145396554 cites W1564803943 @default.
- W2145396554 cites W1598370459 @default.
- W2145396554 cites W1711580613 @default.
- W2145396554 cites W1791286506 @default.
- W2145396554 cites W180573463 @default.
- W2145396554 cites W1919772617 @default.
- W2145396554 cites W1951579604 @default.
- W2145396554 cites W1967254027 @default.
- W2145396554 cites W1967832443 @default.
- W2145396554 cites W1973533971 @default.
- W2145396554 cites W1974523504 @default.
- W2145396554 cites W1979940606 @default.
- W2145396554 cites W1986396519 @default.
- W2145396554 cites W1987752391 @default.
- W2145396554 cites W1996887960 @default.
- W2145396554 cites W2008321551 @default.
- W2145396554 cites W2011581669 @default.
- W2145396554 cites W2019249381 @default.
- W2145396554 cites W2027691956 @default.
- W2145396554 cites W2028799037 @default.
- W2145396554 cites W2031162756 @default.
- W2145396554 cites W2032097381 @default.
- W2145396554 cites W2044949543 @default.
- W2145396554 cites W2050610034 @default.
- W2145396554 cites W2052200503 @default.
- W2145396554 cites W2061772094 @default.
- W2145396554 cites W2062583464 @default.
- W2145396554 cites W2065276595 @default.
- W2145396554 cites W2069222845 @default.
- W2145396554 cites W2072889251 @default.
- W2145396554 cites W2078947652 @default.
- W2145396554 cites W2079600652 @default.
- W2145396554 cites W2081099593 @default.
- W2145396554 cites W2086091822 @default.
- W2145396554 cites W2096005812 @default.
- W2145396554 cites W2097961690 @default.
- W2145396554 cites W2099781374 @default.
- W2145396554 cites W2106706966 @default.
- W2145396554 cites W2108476505 @default.
- W2145396554 cites W2109719686 @default.
- W2145396554 cites W2113508044 @default.
- W2145396554 cites W2115852179 @default.
- W2145396554 cites W2116894414 @default.
- W2145396554 cites W2120934776 @default.
- W2145396554 cites W2121367129 @default.
- W2145396554 cites W2124435032 @default.
- W2145396554 cites W2130620403 @default.
- W2145396554 cites W2130873319 @default.
- W2145396554 cites W2132694787 @default.
- W2145396554 cites W2132950611 @default.
- W2145396554 cites W2141499810 @default.
- W2145396554 cites W2142927666 @default.
- W2145396554 cites W2144821573 @default.
- W2145396554 cites W2149318232 @default.
- W2145396554 cites W2149993963 @default.
- W2145396554 cites W2155034604 @default.
- W2145396554 cites W2156441380 @default.
- W2145396554 cites W2157300284 @default.
- W2145396554 cites W2160782760 @default.
- W2145396554 cites W2160982584 @default.
- W2145396554 cites W2164109844 @default.
- W2145396554 cites W2164258425 @default.
- W2145396554 cites W2167278223 @default.
- W2145396554 cites W2218232968 @default.
- W2145396554 cites W2325907719 @default.
- W2145396554 cites W2329823270 @default.
- W2145396554 cites W2394860167 @default.
- W2145396554 cites W4233758357 @default.
- W2145396554 cites W4244234315 @default.
- W2145396554 cites W4256509107 @default.
- W2145396554 doi "https://doi.org/10.1086/302825" @default.
- W2145396554 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1288178" @default.
- W2145396554 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10712212" @default.
- W2145396554 hasPublicationYear "2000" @default.
- W2145396554 type Work @default.
- W2145396554 sameAs 2145396554 @default.
- W2145396554 citedByCount "486" @default.
- W2145396554 countsByYear W21453965542012 @default.
- W2145396554 countsByYear W21453965542013 @default.
- W2145396554 countsByYear W21453965542014 @default.
- W2145396554 countsByYear W21453965542015 @default.
- W2145396554 countsByYear W21453965542016 @default.
- W2145396554 countsByYear W21453965542017 @default.
- W2145396554 countsByYear W21453965542018 @default.