Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145424416> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2145424416 abstract "Ionic liquid(IL) is a salt in the liquid state below 100°C and have been considered as eco-friendly solvent that can replace organic solvent due to their unique properties; non-volatility and non-explosiveness. However, the safety of ILs in aquatic environment has not been fully assessed. In this work, we investigated the effects of ILs on ion channels when they are incorporated into a lipid bilayer. We chose gramicidin A (gA) as our model protein that selectively permeates cations. The ion permeability of gA varies depending on the type of ILs. In order to measure channel activities of gAs, we used two methods; fluorescence assay utilizing using stop-flow spectrometer and measurement of ion currents across lipid bilayers using a patch clamp instrument. Furthermore, we revealed that alkyl chain length of ILs and ion strength of buffer play important roles in ion permeability and confirmed how electrostatic effects due to charges on the membrane surface changed depending on ion strength of buffer using MD simulation. As a result, we should be able to design safer ILs by taking our results into account." @default.
- W2145424416 created "2016-06-24" @default.
- W2145424416 creator A5012166978 @default.
- W2145424416 creator A5014240620 @default.
- W2145424416 creator A5022130187 @default.
- W2145424416 creator A5047544881 @default.
- W2145424416 creator A5061936591 @default.
- W2145424416 creator A5062206393 @default.
- W2145424416 creator A5067125430 @default.
- W2145424416 creator A5071852246 @default.
- W2145424416 date "2015-01-01" @default.
- W2145424416 modified "2023-09-29" @default.
- W2145424416 title "Elucidation of the Channel Activities of Gramicidin a in the Presence of Ionic Liquids (ILS) using Model Cell Membranes" @default.
- W2145424416 doi "https://doi.org/10.1016/j.bpj.2014.11.2108" @default.
- W2145424416 hasPublicationYear "2015" @default.
- W2145424416 type Work @default.
- W2145424416 sameAs 2145424416 @default.
- W2145424416 citedByCount "0" @default.
- W2145424416 crossrefType "journal-article" @default.
- W2145424416 hasAuthorship W2145424416A5012166978 @default.
- W2145424416 hasAuthorship W2145424416A5014240620 @default.
- W2145424416 hasAuthorship W2145424416A5022130187 @default.
- W2145424416 hasAuthorship W2145424416A5047544881 @default.
- W2145424416 hasAuthorship W2145424416A5061936591 @default.
- W2145424416 hasAuthorship W2145424416A5062206393 @default.
- W2145424416 hasAuthorship W2145424416A5067125430 @default.
- W2145424416 hasAuthorship W2145424416A5071852246 @default.
- W2145424416 hasBestOaLocation W21454244161 @default.
- W2145424416 hasConcept C113196181 @default.
- W2145424416 hasConcept C121332964 @default.
- W2145424416 hasConcept C145148216 @default.
- W2145424416 hasConcept C154881586 @default.
- W2145424416 hasConcept C159467904 @default.
- W2145424416 hasConcept C161790260 @default.
- W2145424416 hasConcept C170493617 @default.
- W2145424416 hasConcept C178790620 @default.
- W2145424416 hasConcept C184651966 @default.
- W2145424416 hasConcept C185592680 @default.
- W2145424416 hasConcept C187428577 @default.
- W2145424416 hasConcept C2778086801 @default.
- W2145424416 hasConcept C2779650302 @default.
- W2145424416 hasConcept C2780263894 @default.
- W2145424416 hasConcept C2780471494 @default.
- W2145424416 hasConcept C39944091 @default.
- W2145424416 hasConcept C41625074 @default.
- W2145424416 hasConcept C43617362 @default.
- W2145424416 hasConcept C50254741 @default.
- W2145424416 hasConcept C55493867 @default.
- W2145424416 hasConcept C62520636 @default.
- W2145424416 hasConcept C91881484 @default.
- W2145424416 hasConceptScore W2145424416C113196181 @default.
- W2145424416 hasConceptScore W2145424416C121332964 @default.
- W2145424416 hasConceptScore W2145424416C145148216 @default.
- W2145424416 hasConceptScore W2145424416C154881586 @default.
- W2145424416 hasConceptScore W2145424416C159467904 @default.
- W2145424416 hasConceptScore W2145424416C161790260 @default.
- W2145424416 hasConceptScore W2145424416C170493617 @default.
- W2145424416 hasConceptScore W2145424416C178790620 @default.
- W2145424416 hasConceptScore W2145424416C184651966 @default.
- W2145424416 hasConceptScore W2145424416C185592680 @default.
- W2145424416 hasConceptScore W2145424416C187428577 @default.
- W2145424416 hasConceptScore W2145424416C2778086801 @default.
- W2145424416 hasConceptScore W2145424416C2779650302 @default.
- W2145424416 hasConceptScore W2145424416C2780263894 @default.
- W2145424416 hasConceptScore W2145424416C2780471494 @default.
- W2145424416 hasConceptScore W2145424416C39944091 @default.
- W2145424416 hasConceptScore W2145424416C41625074 @default.
- W2145424416 hasConceptScore W2145424416C43617362 @default.
- W2145424416 hasConceptScore W2145424416C50254741 @default.
- W2145424416 hasConceptScore W2145424416C55493867 @default.
- W2145424416 hasConceptScore W2145424416C62520636 @default.
- W2145424416 hasConceptScore W2145424416C91881484 @default.
- W2145424416 hasLocation W21454244161 @default.
- W2145424416 hasOpenAccess W2145424416 @default.
- W2145424416 hasPrimaryLocation W21454244161 @default.
- W2145424416 hasRelatedWork W1037158148 @default.
- W2145424416 hasRelatedWork W1971276054 @default.
- W2145424416 hasRelatedWork W1976456827 @default.
- W2145424416 hasRelatedWork W1994440969 @default.
- W2145424416 hasRelatedWork W1995159519 @default.
- W2145424416 hasRelatedWork W2013965456 @default.
- W2145424416 hasRelatedWork W2086782779 @default.
- W2145424416 hasRelatedWork W2090477385 @default.
- W2145424416 hasRelatedWork W2147176003 @default.
- W2145424416 hasRelatedWork W2308098819 @default.
- W2145424416 hasRelatedWork W2367588764 @default.
- W2145424416 hasRelatedWork W2376049302 @default.
- W2145424416 hasRelatedWork W2484886228 @default.
- W2145424416 hasRelatedWork W2560539681 @default.
- W2145424416 hasRelatedWork W2985946076 @default.
- W2145424416 hasRelatedWork W3005103093 @default.
- W2145424416 hasRelatedWork W3107867342 @default.
- W2145424416 hasRelatedWork W3132552409 @default.
- W2145424416 hasRelatedWork W3133420368 @default.
- W2145424416 hasRelatedWork W866730241 @default.
- W2145424416 isParatext "false" @default.
- W2145424416 isRetracted "false" @default.
- W2145424416 magId "2145424416" @default.
- W2145424416 workType "article" @default.