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- W2145434152 abstract "Brain metastases are the most common type of intracranial tumor and carry a poor prognosis. Recent retrospective series have suggested 3T magnetic resonance imaging (MRI) may detect more lesions when compared with 1.5T MRI. The aim of the current study is to compare the number of lesions detected by 1.5T and 3T MRI in patients planned for SRS using both imaging modalities. Records of patients treated with stereotactic radiosurgery for intracranial lesions at UCSD between December 2005 and December 2010 were reviewed. Patients were eligible if they had 1.5T MRI and a 3T MRI preceding treatment and the 1.5T MRI was performed first. The radiology reports were reviewed and the number of lesions recorded. Fifty-nine pairs of scans (1.5T and 3T) were reviewed, with a median time between scans of 19 days (range 2-69). Tumor sites of origin were lung in 29 (49.2%), breast in 14 (23.7%), melanoma in 10 (16.9%), and other in 6 (10.2%). There was no increase in the number of lesions for 43 pairs (72.9%, 95% CI, 61.6-84.2%) and increased number of lesions for 16 pairs (27.1%, 95% CI, 15.8%-38.4). The difference in number of lesions ranged from 1-8. There was no difference in the proportion of breast (p = 0.495), lung (p = 0.937), and melanoma (p = 0.71) patients between the two groups. Mean time between scans for patients with increased number of lesions (28.8 days ± 20.7) was longer than patients with no increase (20.4 days, ± 12.9), but this difference did not reach statistical significance (p = 0.14). A significant number of patients were found to have an increased number of lesions on 3T MRI when compared to 1.5T MRI. This may have implications on symptom management and prognosis in patients with intracranial metastatic disease. Larger, prospective trials are needed to better establish the role of 3T MRI in detecting additional lesions prior to stereotactic radiosurgery." @default.
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- W2145434152 date "2011-10-01" @default.
- W2145434152 modified "2023-09-26" @default.
- W2145434152 title "Difference in Number of Brain Metastases Detected using 1.5T and 3T MRI in Patients Treated with Stereotactic Radiosurgery" @default.
- W2145434152 doi "https://doi.org/10.1016/j.ijrobp.2011.06.1781" @default.
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