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- W2145486578 abstract "Advances in our understanding of the molecular mechanisms of homologous recombination have come from a variety of experimental approaches. Genetic analyses of mutants defective in recombination have identified genes whose functions are required for recombination and have led to the concept of alternative pathways of recombination. Biochemical analyses of wild-type and mutant cells have identified enzymatic activities associated with some of these genes and therefore necessary for recombination. Studies on the transfer of genetic information and material from parental DNA molecules to recombinant DNA molecules have shown recombination in some cases to be a breakage and reunion reaction with production of hybrid DNA and have led to the proposal of models of recombination. These genetic studies have also shown that homologous recombination is sometimes controlled by special DNA sites that act either negatively or positively in their vicinity. Collectively, these approaches promise to lead to a more complete molecular description..." @default.
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- W2145486578 date "1984-01-01" @default.
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- W2145486578 title "Roles of RecBC Enzyme and Chi Sites in Homologous Recombination" @default.
- W2145486578 doi "https://doi.org/10.1101/sqb.1984.049.01.055" @default.
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