Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145532419> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2145532419 endingPage "81" @default.
- W2145532419 startingPage "2377" @default.
- W2145532419 abstract "The regulation of base excision repair during cell proliferation was examined as a function of the rate of cell growth. Normal human skin fibroblasts (mean generation time, 27.64 hr) and hamster fibroblasts (mean generation time, 13.79 hr) were utilized to examine this relationship. The regulation of base excision repair in each cell type was examined by quantitating (a) the activity of the base excision repair enzyme, uracil DNA glycosylase, during asynchronous cell proliferation; and (b) glycosylase activity during cell proliferation after exposure to dimethyl sulfate. In both cell types, uracil DNA glycosylase was increased as a function of cell proliferation. The extent of enhancement was greater in the baby hamster kidney cells than in the normal human skin cells (9.5-fold versus 4-fold, respectively). In baby hamster kidney cells, cell proliferation as well as the enhancement of uracil DNA glycosylase was unaffected by exposure to 20 microM dimethyl sulfate. In contrast, the exposure of normal human skin cells to 20 microM dimethyl sulfate reduced the extent of cell growth and, consequently, the proliferative-dependent stimulation of uracil DNA glycosylase. These results suggest that the regulation of base excision repair is directly proportional to the proliferative rate characteristic of a given cell population." @default.
- W2145532419 created "2016-06-24" @default.
- W2145532419 creator A5002956067 @default.
- W2145532419 creator A5006788670 @default.
- W2145532419 creator A5035866344 @default.
- W2145532419 date "1984-06-01" @default.
- W2145532419 modified "2023-09-23" @default.
- W2145532419 title "Positive correlation between the extent of cell proliferation and the regulation of base excision repair." @default.
- W2145532419 cites W138084604 @default.
- W2145532419 cites W1500282856 @default.
- W2145532419 cites W1554627281 @default.
- W2145532419 cites W1566943875 @default.
- W2145532419 cites W1579327871 @default.
- W2145532419 cites W1758147550 @default.
- W2145532419 cites W1775749144 @default.
- W2145532419 cites W1971292865 @default.
- W2145532419 cites W1978437631 @default.
- W2145532419 cites W1980935809 @default.
- W2145532419 cites W2004947378 @default.
- W2145532419 cites W2010254528 @default.
- W2145532419 cites W2014491732 @default.
- W2145532419 cites W2016734063 @default.
- W2145532419 cites W2037951454 @default.
- W2145532419 cites W2038652104 @default.
- W2145532419 cites W2043132016 @default.
- W2145532419 cites W2065926360 @default.
- W2145532419 cites W2066334190 @default.
- W2145532419 cites W2081950167 @default.
- W2145532419 cites W2101111021 @default.
- W2145532419 cites W2154214377 @default.
- W2145532419 cites W2165431239 @default.
- W2145532419 cites W2174274173 @default.
- W2145532419 cites W2438674803 @default.
- W2145532419 cites W350487362 @default.
- W2145532419 cites W438897964 @default.
- W2145532419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6722777" @default.
- W2145532419 hasPublicationYear "1984" @default.
- W2145532419 type Work @default.
- W2145532419 sameAs 2145532419 @default.
- W2145532419 citedByCount "12" @default.
- W2145532419 crossrefType "journal-article" @default.
- W2145532419 hasAuthorship W2145532419A5002956067 @default.
- W2145532419 hasAuthorship W2145532419A5006788670 @default.
- W2145532419 hasAuthorship W2145532419A5035866344 @default.
- W2145532419 hasConcept C134935766 @default.
- W2145532419 hasConcept C1491633281 @default.
- W2145532419 hasConcept C153911025 @default.
- W2145532419 hasConcept C185592680 @default.
- W2145532419 hasConcept C187206112 @default.
- W2145532419 hasConcept C192396546 @default.
- W2145532419 hasConcept C2778575167 @default.
- W2145532419 hasConcept C2778711568 @default.
- W2145532419 hasConcept C552990157 @default.
- W2145532419 hasConcept C55493867 @default.
- W2145532419 hasConcept C62112901 @default.
- W2145532419 hasConcept C86803240 @default.
- W2145532419 hasConcept C95444343 @default.
- W2145532419 hasConceptScore W2145532419C134935766 @default.
- W2145532419 hasConceptScore W2145532419C1491633281 @default.
- W2145532419 hasConceptScore W2145532419C153911025 @default.
- W2145532419 hasConceptScore W2145532419C185592680 @default.
- W2145532419 hasConceptScore W2145532419C187206112 @default.
- W2145532419 hasConceptScore W2145532419C192396546 @default.
- W2145532419 hasConceptScore W2145532419C2778575167 @default.
- W2145532419 hasConceptScore W2145532419C2778711568 @default.
- W2145532419 hasConceptScore W2145532419C552990157 @default.
- W2145532419 hasConceptScore W2145532419C55493867 @default.
- W2145532419 hasConceptScore W2145532419C62112901 @default.
- W2145532419 hasConceptScore W2145532419C86803240 @default.
- W2145532419 hasConceptScore W2145532419C95444343 @default.
- W2145532419 hasIssue "6" @default.
- W2145532419 hasLocation W21455324191 @default.
- W2145532419 hasOpenAccess W2145532419 @default.
- W2145532419 hasPrimaryLocation W21455324191 @default.
- W2145532419 hasRelatedWork W1964561303 @default.
- W2145532419 hasRelatedWork W1970566518 @default.
- W2145532419 hasRelatedWork W1989944424 @default.
- W2145532419 hasRelatedWork W2020339673 @default.
- W2145532419 hasRelatedWork W2037838723 @default.
- W2145532419 hasRelatedWork W2053801105 @default.
- W2145532419 hasRelatedWork W2145532419 @default.
- W2145532419 hasRelatedWork W2575586677 @default.
- W2145532419 hasRelatedWork W2981651136 @default.
- W2145532419 hasRelatedWork W331372425 @default.
- W2145532419 hasVolume "44" @default.
- W2145532419 isParatext "false" @default.
- W2145532419 isRetracted "false" @default.
- W2145532419 magId "2145532419" @default.
- W2145532419 workType "article" @default.