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• W2145586033 abstract "At the beginning of the acquired immune deficiency syndrome (AIDS) era, nearly 15 yrs ago, Pneumocystis carinii pneumonia (PCP) was the most common human immunodeficiency virus (HIV)-related complication. PCP represented about 60% of the initial case-defining events of AIDS patients [1]. Almost 80% of HIV and AIDS patients experienced at least one episode of PCP in the course of their HIV infection [2, 3]. Thanks to secondary prophylaxis, the number of relapses of PCP has recently declined. But PCP is still the most commonly reported AIDS-associated diagnosis amongst HIV-infected individuals in Western industrialized countries [4]. Mortality was high, as the disease was not recognized early enough in many cases and the benefits of systemic steroids were not known at that point of time [5, 6]. Increased risks for PCP are: a CD4+ count 12 months of inhalation time) failure, and found no difference between these two groups. Presentation with upper lobe infections was also a radiographic pattern of late failures. EDELSTEIN and MCCABE [30] first described this atypical presentation in 1990 and, in contrast to EWIG et al. [28], they observed complicated courses, such as cavities and pneumothoraces. Lung cavitation in PCP may also occur without inhaled pentamidine prophylaxis [31]. EDITORIAL" @default.
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• W2145586033 date "1996-05-01" @default.
• W2145586033 modified "2023-09-26" @default.
• W2145586033 title "Primary and secondary prophylaxis for Pneumocystis carinii related complications in HIV patients" @default.
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• W2145586033 doi "https://doi.org/10.1183/09031936.96.09050868" @default.
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