FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145607054> ?p ?o ?g. }

• W2145607054 endingPage "71" @default.
• W2145607054 startingPage "66" @default.
• W2145607054 abstract "The occurrence of two or more cases of multiple myeloma (MM) in the same family has been reported from time to time. The current study is the first population- and cancer-registry-based survey to investigate familiality of premalignant or malignant B-cell proliferation.A family registry of 218 multiple myeloma cases was compared with the records of the Icelandic Cancer Registry in order to analyze the pedigrees for the occurrence of families with multiple cases of paraproteinemia and hematologic malignancies.The relative risk of developing monoclonal gammopathies of unknown significance (MGUS) was not increased among first-degree relatives of MM patients, but there was a significantly increased risk of developing MM for females separately (RR = 3.23, CI 1.17-7.01) and for males and females combined (RR = 2.33, CI 1.12-4.26). Analysis for all hematologic malignancies showed an increased risk for female relatives of MM patients (RR = 1.95, CI 1.10-3.20). Eight families were identified in which the propositus with MM had > 1 relatives with MGUS and > 1 with another hematologic malignancy, including 4 families with another relative with MM. In three families both myeloid and lymphoid malignancies occurred.Although inheritance does not appear to be a major risk factor for the development of paraproteinemias a significant risk of developing MM was found for female relatives. The occurrence of multiple cases of benign and malignant paraproteinemias in a few families does suggest a hereditary contribution. Further studies of such families might reveal clues on pathogenesis." @default.
• W2145607054 created "2016-06-24" @default.
• W2145607054 creator A5002093381 @default.
• W2145607054 creator A5005229123 @default.
• W2145607054 creator A5021056191 @default.
• W2145607054 creator A5028571536 @default.
• W2145607054 creator A5036365931 @default.
• W2145607054 creator A5067007324 @default.
• W2145607054 creator A5068342767 @default.
• W2145607054 date "2005-01-01" @default.
• W2145607054 modified "2023-09-23" @default.
• W2145607054 title "Familiality of benign and malignant paraproteinemias. A population-based cancer-registry study of multiple myeloma families." @default.
• W2145607054 cites W1599996336 @default.
• W2145607054 cites W1982411778 @default.
• W2145607054 cites W1994362306 @default.
• W2145607054 cites W1996912787 @default.
• W2145607054 cites W2005977428 @default.
• W2145607054 cites W2006569323 @default.
• W2145607054 cites W2008113765 @default.
• W2145607054 cites W2010103250 @default.
• W2145607054 cites W2016018630 @default.
• W2145607054 cites W2019368554 @default.
• W2145607054 cites W2027940526 @default.
• W2145607054 cites W2034448033 @default.
• W2145607054 cites W2034490744 @default.
• W2145607054 cites W2038968394 @default.
• W2145607054 cites W2039874952 @default.
• W2145607054 cites W2046715274 @default.
• W2145607054 cites W2063193300 @default.
• W2145607054 cites W2065872310 @default.
• W2145607054 cites W2066778514 @default.
• W2145607054 cites W2078708658 @default.
• W2145607054 cites W2088868464 @default.
• W2145607054 cites W2093708914 @default.
• W2145607054 cites W2104152689 @default.
• W2145607054 cites W211129604 @default.
• W2145607054 cites W2126214217 @default.
• W2145607054 cites W2160479411 @default.
• W2145607054 cites W2403668281 @default.
• W2145607054 cites W2409658803 @default.
• W2145607054 cites W2430033940 @default.
• W2145607054 cites W2435058349 @default.
• W2145607054 cites W2435252424 @default.
• W2145607054 cites W75280112 @default.
• W2145607054 cites W86053206 @default.
• W2145607054 cites W2400533233 @default.
• W2145607054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15642671" @default.
• W2145607054 hasPublicationYear "2005" @default.
• W2145607054 type Work @default.
• W2145607054 sameAs 2145607054 @default.
• W2145607054 citedByCount "22" @default.
• W2145607054 countsByYear W21456070542013 @default.
• W2145607054 countsByYear W21456070542014 @default.
• W2145607054 countsByYear W21456070542016 @default.
• W2145607054 countsByYear W21456070542017 @default.
• W2145607054 countsByYear W21456070542018 @default.
• W2145607054 countsByYear W21456070542020 @default.
• W2145607054 countsByYear W21456070542022 @default.
• W2145607054 crossrefType "journal-article" @default.
• W2145607054 hasAuthorship W2145607054A5002093381 @default.
• W2145607054 hasAuthorship W2145607054A5005229123 @default.
• W2145607054 hasAuthorship W2145607054A5021056191 @default.
• W2145607054 hasAuthorship W2145607054A5028571536 @default.
• W2145607054 hasAuthorship W2145607054A5036365931 @default.
• W2145607054 hasAuthorship W2145607054A5067007324 @default.
• W2145607054 hasAuthorship W2145607054A5068342767 @default.
• W2145607054 hasConcept C121608353 @default.
• W2145607054 hasConcept C126322002 @default.
• W2145607054 hasConcept C143998085 @default.
• W2145607054 hasConcept C2776364478 @default.
• W2145607054 hasConcept C2778527826 @default.
• W2145607054 hasConcept C2779399171 @default.
• W2145607054 hasConcept C2908647359 @default.
• W2145607054 hasConcept C44249647 @default.
• W2145607054 hasConcept C50440223 @default.
• W2145607054 hasConcept C71924100 @default.
• W2145607054 hasConcept C82789193 @default.
• W2145607054 hasConcept C99454951 @default.
• W2145607054 hasConceptScore W2145607054C121608353 @default.
• W2145607054 hasConceptScore W2145607054C126322002 @default.
• W2145607054 hasConceptScore W2145607054C143998085 @default.
• W2145607054 hasConceptScore W2145607054C2776364478 @default.
• W2145607054 hasConceptScore W2145607054C2778527826 @default.
• W2145607054 hasConceptScore W2145607054C2779399171 @default.
• W2145607054 hasConceptScore W2145607054C2908647359 @default.
• W2145607054 hasConceptScore W2145607054C44249647 @default.
• W2145607054 hasConceptScore W2145607054C50440223 @default.
• W2145607054 hasConceptScore W2145607054C71924100 @default.
• W2145607054 hasConceptScore W2145607054C82789193 @default.
• W2145607054 hasConceptScore W2145607054C99454951 @default.
• W2145607054 hasIssue "1" @default.
• W2145607054 hasLocation W21456070541 @default.
• W2145607054 hasOpenAccess W2145607054 @default.
• W2145607054 hasPrimaryLocation W21456070541 @default.
• W2145607054 hasRelatedWork W1983578060 @default.
• W2145607054 hasRelatedWork W1984534203 @default.
• W2145607054 hasRelatedWork W1990387412 @default.
• W2145607054 hasRelatedWork W1994362306 @default.

• next